IL-1β-IN-4
IL-1β-IN-4 is a selective IL-1β competitive binder. IL-1β-IN-4 interferes with the interaction between IL-1β and its cognate receptor IL-1R1, with an IC50 of 8.3 μM. IL-1β-IN-4 can be used in studies related to inflammatory and immune diseases.
For research use only. We do not sell to patients.
- CAS No.: 3056856-56-2
- Formula: C37H42N6O8S
- Molecular Weight:730.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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IL-1β |
IL-1β-IN-4 ((S)-7) inhibits the IL-1β:IL-1R1 interaction in a TR-FRET binding assay with an IC50 of 8.3 μM; it also weakly inhibits the IL-1α:IL-1R1 interaction with an IC50 of 99 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3056856-56-2
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Molecular Weight 730.84
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Formula C37H42N6O8S
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SMILES
C(=O)(C=1N=C2C(=CC(C(O)=O)=CN2C1)C3=CC(C(C)C)=C(C=O)C=C3)N4[C@H](C(NCCN5CCOCC5)=O)CCN(S(=O)(=O)C6=CC=CC=C6)CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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