2. Immunology/Inflammation
  3. Interleukin Related
  4. IL-1β-IN-4

IL-1β-IN-4 is a selective IL-1β competitive binder. IL-1β-IN-4 interferes with the interaction between IL-1β and its cognate receptor IL-1R1, with an IC50 of 8.3 μM. IL-1β-IN-4 can be used in studies related to inflammatory and immune diseases.

For research use only. We do not sell to patients.

IL-1β-IN-4

IL-1β-IN-4 Chemical Structure

CAS No. : 3056856-56-2

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IL-1β-IN-4 Related Antibodies

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Description

IL-1β-IN-4 is a selective IL-1β competitive binder. IL-1β-IN-4 interferes with the interaction between IL-1β and its cognate receptor IL-1R1, with an IC50 of 8.3 μM. IL-1β-IN-4 can be used in studies related to inflammatory and immune diseases[1].

IC50 & Target[1]

IL-1β

 

In Vitro

IL-1β-IN-4 ((S)-7) inhibits the IL-1β:IL-1R1 interaction in a TR-FRET binding assay with an IC50 of 8.3 μM; it also weakly inhibits the IL-1α:IL-1R1 interaction with an IC50 of 99 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

IL-1β-IN-4 Related Antibodies
Molecular Weight

730.84

Formula

C37H42N6O8S
CAS No.
SMILES

C(=O)(C=1N=C2C(=CC(C(O)=O)=CN2C1)C3=CC(C(C)C)=C(C=O)C=C3)N4[C@H](C(NCCN5CCOCC5)=O)CCN(S(=O)(=O)C6=CC=CC=C6)CC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IL-1β-IN-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IL-1β-IN-43056856-56-2Interleukin RelatedILTR-FRET binding assayIL-1αIL-1βIL-1R1Inhibitorinhibitorinhibit

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