51 Results for "

IgG2κ

" in MedChemExpress (MCE) Product Catalog:
Products (51)

51 Results for "IgG2κ" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P990587

Target:  

CD28

Research Areas:  

Inflammation/Immunology

FR104 is a humanized antibody expressed in CHO cells that targets CD28. FR104 comprises a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.08 kDa. The isotype control for FR104 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).
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1 Cited Publications
Cat. No.: HY-P99414
CAS No.: 1523164-68-2
Synonyms: AMG 557
Prezalumab (AMG 557) is a humanized IgG2 monoclonal antibody targeting ICOSL. Prezalumab inhibits T cell activation and related immune responses by binding to ICOSL and blocking the interaction between ICOS and ICOSL. Prezalumab can be used in the research of autoimmune diseases and inflammatory diseases such as systemic lupus erythematosus. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002) [2].
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1 Cited Publications
Cat. No.: HY-P990010
CAS No.: 2609642-90-0
Synonyms: IXT-M200

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Devextinetug (IXT-M200) is a chimeric anti-methamphetamine, human-derived IgG2κ antibody .
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Cat. No.: HY-P99002

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Human IgG2 kappa, Isotype Control is a human monoclonal antibody serving as an isotype control for human IgG2κ antibodies such as Cepeprubart (HY-P990732) and Ersodetug (HY-P990712). Human IgG2 kappa, Isotype Control can be used in T cell research .
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Cat. No.: HY-P99909
CAS No.: 2408850-14-4
Synonyms: PF-06863135; RN-613

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Elranatamab (PF-06863135) is an anti-CD3E/TNFRSF17 human IgG2κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P99677
CAS No.: 2447755-72-6
Synonyms: ZTS-00075623
Izenivetmab (ZTS-00075623) is an anti-NGFB IgG2κ monoclonal antibody. Izenivetmab shows anti-inflammatory and analgesic effects by targeting anti-nerve growth factor (NGF). Izenivetmab can be used for the research of osteoarthritis .
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Cat. No.: HY-P990012
CAS No.: 2744320-12-3
Synonyms: EBI-031

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Vamikibart (EBI-031) is a humanized IgG2κ monoclonal antibody targeting IL-6, with high binding affinity for IL-6 and the IL-6/IL-6R complex. Vamikibart reduces central retinal thickness, resolves intraretinal and subretinal foveal fluid, and decreases the levels of intraocular inflammatory markers. Vamikibart can be used in studies of uveitic macular edema (UME) secondary to non-infectious uveitis [2].
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Cat. No.: HY-P990013
CAS No.: 2642374-02-3
Synonyms: Glutazumab; GMA-102; GMA-105

Target:  

GCGR

Research Areas:  

Metabolic Disease

Gulgafafusp alfa is a human IgG2κ antibody targeting the glucagon-like peptide 1 receptor GLP1R .
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Cat. No.: HY-P990713
CAS No.: 2750248-93-0
Synonyms: VTQ-2101

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Nolavetbart (VTQ-2101) is an anti-Canlupfam IL31RA IgG2 κ monoclonal antibody. Nolavetbart can be used in research on inflammation-related diseases .
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Cat. No.: HY-P990313

Research Areas:  

Inflammation/Immunology

ABX-IL8 is a human-derived antibody expressed in CHO cells, targeting CXCL8/IL-8. ABX-IL8 contains a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 143.94 kDa. The isotype control for ABX-IL8 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P99641
CAS No.: 1808081-43-7

Research Areas:  

Cancer

Gilvetmab is a canine-derived anti-cPD-1 monoclonal antibody, as well as an immune activator/antitumor agent. Gilvetmab binds to canine PD-1, blocks the interaction of PD-1/PD-L1/L2, prevents immunosuppression, reactivates antitumor responses, induces tumor regression or disease stabilization, and may also trigger pseudoprogression. Gilvetmab can be used in research related to malignant melanoma and mast cell tumors [2] .
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Cat. No.: HY-P990011
CAS No.: 2747959-38-0
Synonyms: ACU-193

Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Sabirnetug is a humanized IgG2κ antibody targeting the Amyloid-β A4 precursor protein.
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Cat. No.: HY-P990699
CAS No.: 2641479-65-2
Synonyms: ZTS-00008183

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Riltovetbart is a canine-derived IgG2 κ monoclonal antibody raised against Canlupfam IL13 .
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Cat. No.: HY-P990712
CAS No.: 2410976-61-1
Synonyms: RZ-358; XOMA 358

Target:  

Insulin Receptor

Research Areas:  

Inflammation/Immunology

Ersodetug is an anti-INSR (insulin receptor) human IgG2 κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P991048
CAS No.: 2243120-07-0

Target:  

c-Fms

Research Areas:  

Cancer

AMG-820 is a fully human IgG2 antibody that targets CSF-1R. AMG-820 inhibits binding of the ligands CSF1 and IL34 and subsequent ligand-induced receptor activation. The isotype control for AMG-820 can refer to Human IgG2 kappa, Isotype Control (HY-P99002) .
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Cat. No.: HY-P990625
CAS No.: 1415642-51-1

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

MEDI-3617 is a humanized antibody expressed in CHO cells, targeting Ang2/ANGPT2/Angiopoietin2. MEDI-3617 has a huIgG2 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for MEDI-3617 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P990321
Synonyms: MEDI 8968

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

AMG-108 is a humanized antibody expressed in CHO cells, targeting IL-1R1/CD121a. AMG-108 is composed of a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.62 kDa. The isotype control for AMG-108 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P990315
Synonyms: AGS-16C

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-ENPP3/CD203c Antibody (AGS-16C3F antibody) is a humanized antibody expressed in CHO cells, targeting ENPP3/CD203c. Anti-ENPP3/CD203c Antibody contains a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 154.04 kDa. The isotype control for Anti-ENPP3/CD203c Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P990662
CAS No.: 1535963-91-7

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Sapelizumab is a CHO-expressed humanized antibody targeting IL-6Ra/CD126. Sapelizumab has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Sapelizumab can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P990656

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

RG-6125 is a humanized antibody expressed in CHO, targeting CDH11/Cadherin-11. RG-6125 has a huIgG2 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for RG-6125 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
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