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Sapelizumab

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Sapelizumab is a CHO-expressed humanized antibody targeting IL-6Ra/CD126. Sapelizumab has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Sapelizumab can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

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  • Pureté : 98.31%
  • CAS No.: 1535963-91-7
  • Masse moléculaire:144.26 kDa
  • Stockage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Sapelizumab
  • Experimental Validation Results for Sapelizumab
  • Sapelizumab Chemical Structure
    Sapelizumab Chemical Structure
CAS No.: 1535963-91-7
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Sapelizumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Immobilized IL-6R alpha Protein, Human can bind Sapelizumab. The EC50 for this effect is 91.38 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5×106 U937 cells with Sapelizumab (HY-P990662, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control.

  • Sapelizumab Chemical Structure
    1/16
  • Sapelizumab
  • Immobilized IL-6R alpha Protein, Human can bind Sapelizumab. The EC50 for this effect is 91.38 ng/mL.
  • Flow cytometric analysis of 1.5×106 U937 cells with Sapelizumab (HY-P990662, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control.