Sabirnetug
Based on 1 Customer Validation
Sabirnetug is a humanized IgG2κ antibody targeting the Amyloid-β A4 precursor protein.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 96.84%
- CAS. Nr.: 2747959-38-0
- Molecular Weight:144.78 kDa
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Speicherung:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Isotype
Human IgG2 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
Amyloid Beta/Aβ
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Human IgG2 kappa
Anwendung
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized β-Amyloid (42-1), human (HY-P1362) can bind Sabirnetug. The EC50 for this effect is 42.33 ng/mL. -
Flow cytometric analysis of 1X106 HUVEC cells with Sabirnetug (HY-P990011, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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CAS. Nr. 2747959-38-0
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Appearance Liquid
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Molecular Weight 144.78 kDa
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Color Colorless to light yellow
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SMILES
[Sabirnetug]
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Synonyms
ACU-193
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Versand
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Data Sheet (229 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)