16 Results for "

Ingenol

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "Ingenol" in MCE Product Catalog:

Cat. No.: HY-N0865
CAS No.: 30220-46-3
Synonyms: (-)-Ingenol
Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity.
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5
5 Cited Publications
Cat. No.: HY-B0719
CAS No.: 75567-37-2
Synonyms: Ingenol 3-angelate; PEP005
Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
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3
3 Cited Publications
Cat. No.: HY-P0034
CAS No.: 285570-60-7
Synonyms: Caspase-3 Inhibitor III
Target:  

Caspase Apoptosis

Research Areas:  

Metabolic Disease

Ac-DEVD-CMK (Caspase-3 Inhibitor III) is a selective and irreversible caspase-3 inhibitor. Ac-DEVD-CMK significantly inhibits apoptosis induced by high levels of glucose or Ingenol 3,20-dibenzoate?(HY-137295). Ac-DEVD-CMK can be used in a variety of experimental approaches to inhibit apoptosis .
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Cat. No.: HY-137295
CAS No.: 59086-90-7
Purity:  99.96%
Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells .
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Cat. No.: HY-137242
CAS No.: 52557-26-3
Purity:  99.65%
Ingenol-3-palmitate, an ingenane diterpenoid, is a nature product that could be isolated from the roots of Euphorbia ebracteolata. Ingenol-3-palmitate is a potent HIV-1 (HIV) inhibitor with an IC50 value of 4.1 nM .
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Cat. No.: HY-N0870
CAS No.: 87980-68-5
Synonyms: Ingenol 5,20-acetonide 3-angelate; Ingenol 3-angelate 5,20-acetonide
Ingenol-5,20-acetonide-3-O-angelate is a natural compound.
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Cat. No.: HY-N13191
CAS No.: 83036-64-0
Synonyms: Ingenol 3-benzoate
Ingenol 3-monobenzoate (Ingenol 3-benzoate) is a disgust inducing agent. Ingenol 3-monobenzoate can bind to and activate PKC (Ki=0.14 nM), inhibit the gene expression of phosphoenolpyruvate carboxykinase, thereby inhibiting gluconeogenesis, and increasing blood cortisol levels, producing food aversion .
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Cat. No.: HY-111533
CAS No.: 83036-61-7
Target:  

Drug Derivative HIV

Research Areas:  

Cancer

Ingenol 3-Hexanoate, an ingenol semi-synthetic derivative, is a potent anticancer agent. Ingenol 3-Hexanoate can be used in research of cancer .
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Cat. No.: HY-N0871
CAS No.: 77573-44-5
Synonyms: Ingenol 3,4:5,20-bisacetonide
Ingenol-3,4,5,20-diacetonide is a natural compound.
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Cat. No.: HY-17616
CAS No.: 1383547-60-1
Synonyms: LEO 43204
Target:  

Drug Metabolite

Research Areas:  

Others

Ingenol disoxate (LEO 43204) is a drug metabolite, that exhibits potential in ameliorating actinic keratosis .
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Cat. No.: HY-N7168
CAS No.: 466663-12-7
3-O-(2'E ,4'E-Decadienoyl)-20-O-acetylingenol is a ingenol-type diterpenoid that contains a 2,4-decadienoyloxy group .
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Cat. No.: HY-B0719R
CAS No.: 75567-37-2
Synonyms: Ingenol 3-angelate (Standard); PEP005 (Standard)
Ingenol Mebutate (Standard) is the analytical standard of Ingenol Mebutate. This product is intended for research and analytical applications. Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
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Cat. No.: HY-137037
CAS No.: 39071-33-5
Ingenol 20-palmitate (compound 2) is a diterpene that can be found in Euphorbia lath yris .
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Cat. No.: HY-N7166
CAS No.: 84680-59-1
3-O-(2'E,4'Z-Decadienoyl)ingenol is a natural diterpene that exhibits significant anticomplement activity with an IC50 of 89.5 μM .
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Cat. No.: HY-N7161
CAS No.: 466663-11-6
3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC50s of 8.22 μM and 6.67 μM, respectively .
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