1 Result for "

Jun13296

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Jun13296" in MCE Product Catalog:

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Cat. No.: HY-168916
CAS No.: 3063566-68-4
Target:  

SARS-CoV Virus Protease

Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13  µM, Ki  = 8.8  nM). Jun13296 exhibits potent inhibition against SARS-CoV-2 variants and Nirmatrelvir (HY-138687)-resistant mutants. Jun13296 improves lung viral titers, and prevents lung tissue damage in a SARS-CoV-2 infection model .
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