20 Results for "

KRAS peptide

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "KRAS peptide" in MCE Product Catalog:

Referencia número: HY-156002
No. CAS: 2676177-63-0
Pureza:  99.20%
Synonyms: Paluratide
Target:  

Ras ERK

Áreas de investigación:  

Cancer

LUNA18 is an orally-available cyclic peptide KRAS and ERK inhibitor. LUNA18 phosphorylates ERK and AKT and decreases cell proliferation in RAS-mutated cancer cells. LUNA18 exhibits RAS signal inhibition and potent anti-cancer activities through inhibiting interaction between RAS and guanine nucleotide exchange factors (GEFs) in a mouse xenograft model. LUNA18 shows significant cellular efficacy against cell lines with KRAS genetic alterations, such as colon cancer, stomach cancer, non-small cell lung cancer and pancreaticcancer .
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Referencia número: HY-P3485
No. CAS: 199477-18-4
Target:  

Peptides

Áreas de investigación:  

Inflammation/Immunology

GAGGVGKSAL is the wild-type 10-mer KRAS peptide. GAGGVGKSAL serves as a control .
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Referencia número: HY-147008
No. CAS: 2344825-52-9
Pureza:  99.66%
Áreas de investigación:  

Cancer

XP-524 is a potent BET and EP300 inhibitor. XP-524 shows great tumoricidal activity in vivo. XP-524 prevents KRAS-induced, neoplastic transformation in vivo and extends survival in two transgenic mouse models of aggressive PDAC. XP-524 also enhances the presentation of self-peptide and tumor recruitment of cytotoxic T lymphocytes. XP-524 has the potential for the research of pancreatic ductal adenocarcinoma (PDAC) .
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Referencia número: HY-P11294
No. CAS: 306276-78-8
Target:  

Ras

Áreas de investigación:  

Cancer

KLVVVGADGVGKSALTI is a KRAS G12D targeting peptide that can be used in tumor research .
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Referencia número: HY-P3487
No. CAS: 1223335-84-9
Target:  

Peptides

Áreas de investigación:  

Inflammation/Immunology Cancer

GAGGVGKSA is a wild type KRAS G12D 9mer peptide. GAGGVGKSA can be used as an immunogenic neoantigen for cancer immunotherapy research .
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Referencia número: HY-P2265A
No. CAS: 2896737-31-6
Target:  

SOS1 Ras

Áreas de investigación:  

Cancer

SAH-SOS1A TFA is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity (EC50=106-175 nM). SAH-SOS1A TFA directly and independently blocks nucleotide association. SAH-SOS1A TFA impairs KRAS-driven cancer cell viability and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS .
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Referencia número: HY-P11355A
Áreas de investigación:  

Cancer

KRAS WT Peptide TFA is the trifluoroacetate salt of KRAS WT Peptide (HY-P11355). KRAS WT Peptide is the normal sequence peptide of the Kirsten rat sarcoma virus (KRAS) gene without oncogenic mutations. KRAS WT Peptide can be used for the study of evaluating the specificity and safety of KRAS-targeted immunotherapies .
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Referencia número: HY-P11357A
Target:  

IFNAR

Áreas de investigación:  

Cancer

KRAS G12C Peptide TFA is the trifluoroacetate salt of KRAS G12C Peptide (HY-P11357). KRAS G12C Peptide is a specific peptide derived from the Kirsten rat sarcoma virus (KRAS) gene carrying the G12C oncogenic mutation. KRAS G12C Peptide induces responses like IFN-γ secretion and cytotoxicity. KRAS G12C Peptide can be used for the study of immune responses against KRAS G12C-mutant tumors .
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Referencia número: HY-P5192
No. CAS: 199476-92-1
Target:  

Ras

Áreas de investigación:  

Cancer

KRAS G12D 8-16 is a mutant KRAS G12D 8-16 peptide .
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Referencia número: HY-P3488
No. CAS: 2032119-68-7
Target:  

Peptides

Áreas de investigación:  

Inflammation/Immunology Cancer

GADGVGKSA is a mutant KRAS G12D 9mer peptide. GADGVGKSA can be used as an immunogenic neoantigen for cancer immunotherapy research .
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Referencia número: HY-P11356
No. CAS: 1932689-39-8
Target:  

Ras MHC

Áreas de investigación:  

Cancer

KRAS G12V Peptide is a polypeptide and epitope derived from KRAS G12V. KRAS G12V Peptide forms a stable, high-affinity peptide-HLA class I complex, which is processed and presented by tumor cells and can be recognized by specific TCR. KRAS G12V Peptide is applicable to research related to metastatic lung cancer .
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Referencia número: HY-P11356A
Target:  

Ras MHC

Áreas de investigación:  

Cancer

KRAS G12V Peptide TFA is a polypeptide and epitope derived from KRAS G12V. KRAS G12V Peptide TFA forms a stable, high-affinity peptide-HLA class I complex, which is processed and presented by tumor cells and can be recognized by specific TCR. KRAS G12V Peptide TFA is applicable to research related to metastatic lung cancer .
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Referencia número: HY-P11355
No. CAS: 1222762-16-4
Target:  

Peptides

Áreas de investigación:  

Cancer

KRAS WT Peptide is the normal sequence peptide of the Kirsten rat sarcoma virus (KRAS) gene without oncogenic mutations. KRAS WT Peptide can be used for the study of evaluating the specificity and safety of KRAS-targeted immunotherapies .
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Referencia número: HY-P11357
No. CAS: 1932689-40-1
Target:  

IFNAR

Áreas de investigación:  

Cancer

KRAS G12C Peptide is a specific peptide derived from the Kirsten rat sarcoma virus (KRAS) gene carrying the G12C oncogenic mutation. KRAS G12C Peptide induces responses like IFN-γ secretion and cytotoxicity. KRAS G12C Peptide can be used for the study of immune responses against KRAS G12C-mutant tumors .
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Referencia número: HY-P3129
No. CAS: 145019-94-9
Target:  

Ras

Áreas de investigación:  

Inflammation/Immunology Cancer

KRAS G13D peptide, 25 mer, a KRAS activating oncogene mutation peptide, is an immune potentiator extracted from patent WO2018144775A1. KRAS G13D peptide, 25 mer can be used to prepare KRAS vaccine .
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Referencia número: HY-P2265
No. CAS: 1652561-87-9
Target:  

SOS1 Ras

Áreas de investigación:  

Cancer

SAH-SOS1A is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity (EC50=106-175 nM), directly and independently blocks nucleotide association, impairs KRAS-driven cancer cell viability, and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS .
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Referencia número: HY-P3486
No. CAS: 199477-24-2
Target:  

Peptides

Áreas de investigación:  

Inflammation/Immunology Cancer

GADGVGKSAL is a mutant KRAS G12D 10mer peptide. GADGVGKSAL can be used as an immunogenic neoantigen for cancer immunotherapy research .
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Referencia número: HY-P10847
No. CAS: 2549046-46-8
Target:  

Ras

Áreas de investigación:  

Cancer

KS-58 is a KRpep-2d (HY-P3277) derivative. KS-58 is a K-Ras (G12D) inhibitory peptide that selectively binds K-Ras. KS-58 can enter cells and block intracellular Ras interaction with effector proteins. KS-58 inhibits the proliferation of tumor cells and has antitumor activity .
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Referencia número: HY-121459
No. CAS: 22862-63-1
Target:  

HSP Ras

Neoantimycin is a GRP78/BiP and K-Ras regulator with anticancer activity. Its biosynthesis is catalyzed by a hybrid nonribosomal peptide synthetase/polyketide synthase (NRPS/PKS) system .
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Referencia número: HY-183553
No. CAS: 2874214-01-2
Target:  

Ras

Áreas de investigación:  

Cancer

AUBE00 is an orally active, selective cyclic peptide pan-KRAS inhibitor. AUBE00 selectively binds to the OFF state of KRAS. AUBE00 exhibits anticancer activity against RAS wild-type colorectal cancer. The combination of AUBE00 with Cetuximab (HY-P9905) produces a synergistic antiproliferative effect .
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