1932689-39-8
Chemical Structure
KRAS G12V Peptide
- CAS No.: 1932689-39-8
- Formula:C40H73N11O11
- Molecular Weight:884.07
InChIKey: UYKUHSNOCBBLBM-CDHXOJBRSA-N
SMILES: O=C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(NCC(N[C@@H](C)C(N[C@@H](C(C)C)C(NCC(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N
Biological Activity: KRAS G12V Peptide is a polypeptide and epitope derived from KRASG12V. KRAS G12V Peptide forms a stable, high-affinity peptide-HLA class I complex, which is processed and presented by tumor cells and can be recognized by specific TCR. KRAS G12V Peptide is applicable to research related to metastatic lung cancer[1][2].
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KRAS G12V Peptide | KRAS G12V Peptide is a polypeptide and epitope derived from KRASG12V. KRAS G12V Peptide forms a stable, high-affinity peptide-HLA class I complex, which is processed and presented by tumor cells and can be recognized by specific TCR. KRAS G12V Peptide is applicable to research related to metastatic lung cancer. | |||||||||||||||||||||
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- [1]. Bear AS, et al. Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting. Nature communications. 2021 Jul 16;12(1):4365. [Content Brief]
- [2]. Zheng W, et al. Exploring the therapeutic potential of precision T-Cell Receptors (TCRs) in targeting KRAS G12D cancer through development. Oncology research. 2024;32(12):1837-1850. [Content Brief]
Keywords
