GAGGVGKSAL
Based on 1 Customer Validation
GAGGVGKSAL is the wild-type 10-mer KRAS peptide. GAGGVGKSAL serves as a control.
For research use only. We do not sell to patients.
- Purity: 99.64%
- CAS No.: 199477-18-4
- Formula: C34H61N11O12
- Molecular Weight:815.91
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
GAGGVGKSAL is the wild-type 10-mer peptide corresponding to the KRAS G12D mutation. It cannot form stable pMHC complexes with HLA-C08:02 or HLA-C05:01 and has no immunogenicity, indicating that the glycine-to-aspartic acid mutation is critical for pMHC stability[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 199477-18-4
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Appearance Solid
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Molecular Weight 815.91
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Formula C34H61N11O12
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Color White to off-white
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Sequence
Gly-Ala-Gly-Gly-Val-Gly-Lys-Ser-Ala-Leu
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Sequence Shortening
GAGGVGKSAL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (122.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2256 mL | 6.1281 mL | 12.2563 mL | 30.6406 mL |
| 5 mM | 0.2451 mL | 1.2256 mL | 2.4513 mL | 6.1281 mL | |
| 10 mM | 0.1226 mL | 0.6128 mL | 1.2256 mL | 3.0641 mL | |
| 15 mM | 0.0817 mL | 0.4085 mL | 0.8171 mL | 2.0427 mL | |
| 20 mM | 0.0613 mL | 0.3064 mL | 0.6128 mL | 1.5320 mL | |
| 25 mM | 0.0490 mL | 0.2451 mL | 0.4903 mL | 1.2256 mL | |
| 30 mM | 0.0409 mL | 0.2043 mL | 0.4085 mL | 1.0214 mL | |
| 40 mM | 0.0306 mL | 0.1532 mL | 0.3064 mL | 0.7660 mL | |
| 50 mM | 0.0245 mL | 0.1226 mL | 0.2451 mL | 0.6128 mL | |
| 60 mM | 0.0204 mL | 0.1021 mL | 0.2043 mL | 0.5107 mL | |
| 80 mM | 0.0153 mL | 0.0766 mL | 0.1532 mL | 0.3830 mL | |
| 100 mM | 0.0123 mL | 0.0613 mL | 0.1226 mL | 0.3064 mL |