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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
Leflunomide
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "Leflunomide" in MCE Product Catalog:
17
17 Publications Verification
Cat. No.: HY-B0083
CAS No.: 75706-12-6
Synonyms: HWA486; RS-34821; SU101
14
Target:
Research Areas:
Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation.
Synonyms: HR325
Research Areas:
Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor .
Research Areas:
PfDHODH-IN-1 is an analogue of the active metabolite of Leflunomide. PfDHODH-IN-1 is a Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor. PfDHODH-IN-1 has antimalarial activity .
Cat. No.: HY-B0083S
CAS No.: 1189987-23-2
Research Areas:
DHODH-IN-14 (Compound 7l) is a hydroxyfurazan analog of A771726. DHODH-IN-14 is a dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.49 μM for rat liver DHODH. DHODH-IN-14 can be used for rheumatoid arthritis .
Target:
Research Areas:
4-(Trifluoromethyl)aniline (Standard) is the analytical standard of 4-(Trifluoromethyl)aniline. This product is intended for research and analytical applications. 4-(Trifluoromethyl) aniline (4-Aminobenzotrifluoride) is an aromatic amine and also a synthetic building block for fluorinated α-aminophosphonates. 4-(Trifluoromethyl) aniline is an impurity of Leflunomide .
Cat. No.: HY-77324S
CAS No.: 1219795-48-8
Synonyms: 4-Aminobenzotrifluoride-d4
Research Areas:
DHODH-IN-11 (Compound 14b) is a Leflunomide derivative and a weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03 .
Target:
Research Areas:
4-(Trifluoromethyl) aniline (4-Aminobenzotrifluoride) is an aromatic amine and also a synthetic building block for fluorinated α-aminophosphonates. 4-(Trifluoromethyl) aniline is an impurity of Leflunomide .
Cat. No.: HY-B0083R
CAS No.: 75706-12-6
Synonyms: HWA486 (Standard); RS-34821 (Standard); SU101 (Standard)
Category:
Cat. No.: HY-135676
CAS No.: 1263303-93-0
Research Areas:
DHODH-IN-12 (Compound 12b) is a Leflunomide derivative and a weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07 .
Cat. No.: HY-135654
CAS No.: 183946-00-1
Research Areas:
hDHODH-IN-2 is an analogue of the active metabolite of Leflunomide. hDHODH-IN-2 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory activity .
Cat. No.: HY-B0083S1
Synonyms: HWA486-13C6; RS-34821-13C6; SU101-13C6
Cat. No.: HY-Z8375
CAS No.: 1403564-06-6
Synonyms: Leflunomide impurity F
Target:
Research Areas:
Leflunomide impurity 1 (Leflunomide impurity F) is an impurity of Leflunomide.
Cat. No.: HY-W011669
CAS No.: 61643-23-0
Synonyms: Leflunomide 3-Isomer
Target:
Research Areas:
Leflunomide impurity 3 (Leflunomide 3-Isomer) is an impurity of Leflunomide.
Cat. No.: HY-15405R
CAS No.: 163451-81-8
Synonyms: A77 1726 (Standard)
Target:
Research Areas:
Teriflunomide (Standard) is the analytical standard of Teriflunomide. This product is intended for research and analytical applications. Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation.
Cat. No.: HY-135677
CAS No.: 1364791-86-5
Research Areas:
DHODH-IN-13 (Compound 7a) is a hydroxyfurazan analog of A771726. DHODH-IN-13 is a dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 4.3 μM for rat liver DHODH. DHODH-IN-13 can be used for rheumatoid arthritis .
Cat. No.: HY-135679
CAS No.: 1364791-88-7
Research Areas:
DHODH-IN-15 (Compound 7b) is a hydroxyfurazan analog of A771726. DHODH-IN-15 is a dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 11 μM for rat liver DHODH. DHODH-IN-15 can be used for rheumatoid arthritis .
Cat. No.: HY-101813R
CAS No.: 147076-36-6
Synonyms: HR325 (Standard)
Research Areas:
Laflunimus (Standard) is the analytical standard of Laflunimus. This product is intended for research and analytical applications. Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 μM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor .
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