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  3. Leflunomide impurity 7

Leflunomide impurity 7 is an impurity of Leflunomide.

For research use only. We do not sell to patients.

Leflunomide impurity 7

Leflunomide impurity 7 Chemical Structure

CAS No. : 24522-30-3

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10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

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Description

Leflunomide impurity 7 is an impurity of Leflunomide.

Molecular Weight

228.17

Formula

C10H7F3N2O

CAS No.
Appearance

Solid

SMILES

N#CCC(=O)NC1=CC=C(C=C1)C(F)(F)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (438.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3827 mL 21.9135 mL 43.8270 mL
5 mM 0.8765 mL 4.3827 mL 8.7654 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.3827 mL 21.9135 mL 43.8270 mL 109.5674 mL
5 mM 0.8765 mL 4.3827 mL 8.7654 mL 21.9135 mL
10 mM 0.4383 mL 2.1913 mL 4.3827 mL 10.9567 mL
15 mM 0.2922 mL 1.4609 mL 2.9218 mL 7.3045 mL
20 mM 0.2191 mL 1.0957 mL 2.1913 mL 5.4784 mL
25 mM 0.1753 mL 0.8765 mL 1.7531 mL 4.3827 mL
30 mM 0.1461 mL 0.7304 mL 1.4609 mL 3.6522 mL
40 mM 0.1096 mL 0.5478 mL 1.0957 mL 2.7392 mL
50 mM 0.0877 mL 0.4383 mL 0.8765 mL 2.1913 mL
60 mM 0.0730 mL 0.3652 mL 0.7304 mL 1.8261 mL
80 mM 0.0548 mL 0.2739 mL 0.5478 mL 1.3696 mL
100 mM 0.0438 mL 0.2191 mL 0.4383 mL 1.0957 mL
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Leflunomide impurity 7 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Leflunomide impurity 7
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