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LysoTracker

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Biochemical Assay Reagents (2) Calcium Channel (1) Fluorescent Dye (6) Monocarboxylate Transporter (1)
By Research Areas:	Cancer (2) Endocrinology (1) Neurological Disease (1)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1300

LysoTracker Red 10+ Cited Publications LysoTracker Red DND-99	Biochemical Assay Reagents Fluorescent Dye	Others
LysoTracker Red is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .

HY-DY1040

LysoTracker Red (solution)	Fluorescent Dye Biochemical Assay Reagents	Others
LysoTracker Red (solution) is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes . Solvent and concentration: DMSO: 1 mM

HY-D1775

LysoTracker Blue DND-22	Fluorescent Dye	Neurological Disease Cancer
LysoTracker blue DND-22 is a blue fluorescent dye (Ex/Em: 373/422 nm). LysoTracker blue DND-22 stains acidic regions in living cells. LysoTracker blue DND-22 is used in the researches of neurodegenerative diseases and leukemia .

HY-D1694

LysoTracker Yellow HCK 123	Fluorescent Dye	Others
LysoTracker Yellow HCK 123 is a potent yellow membrane-permeable fluorescent probe. LysoTracker Yellow HCK 123 is a weakly basic amine that selectively accumulates in cellular compartments with low luminal pH .

HY-Y1080

N-Acetyl-R-leucine N-Acetyl-D-leucine	Amino Acid Derivatives Monocarboxylate Transporter	Endocrinology
N-Acetyl-R-leucine is an amino-protecting group N-substituted chiral amino acid. N-Acetyl-R-leucine is a PepT1 and MCT1 inhibitor with IC₅₀ of 0.74 and 11 mM, respectively. N-Acetyl-R-leucine can be used for LysoTracker signaling studies .

HY-103305

cis-Ned19	Fluorescent Dye Calcium Channel	Others
cis-Ned19 is an irreversible nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. cis-Ned19 localizes to lysosomes and endolysosomal vesicles, stains two-pore calcium channels and fluorescently labels NAADP receptors (Ex/Em = 365/410 nm) .

HY-D3251

LCP	Fluorescent Dye	Cancer
LCP is a fluorescent probe applicable for subcellular localization. LCP responds to polarity changes in the cellular microenvironment via fluorescence resonance energy transfer, emitting blue fluorescence in low-polarity environments and red fluorescence in high-polarity environments. LCP enables dual-color visualization of dynamic changes in lysosomes and cytoplasmic membranes during drug-induced cell apoptosis, and monitors cell viability through localization and emission color changes. LCP can be used in cancer research .

Cat. No.	Product Name	Type

HY-D1300

LysoTracker Red 10+ Cited Publications LysoTracker Red DND-99	Fluorescent Dye
LysoTracker Red is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .

HY-DY1040

LysoTracker Red (solution)	Fluorescent Dye
LysoTracker Red (solution) is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes . Solvent and concentration: DMSO: 1 mM

LysoTracker Red (solution)

Fluorescent Dye

LysoTracker Red (solution) is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
Solvent and concentration: DMSO: 1 mM

HY-D1775

LysoTracker Blue DND-22	Fluorescent Dye
LysoTracker blue DND-22 is a blue fluorescent dye (Ex/Em: 373/422 nm). LysoTracker blue DND-22 stains acidic regions in living cells. LysoTracker blue DND-22 is used in the researches of neurodegenerative diseases and leukemia .

HY-D1694

LysoTracker Yellow HCK 123	Fluorescent Dye
LysoTracker Yellow HCK 123 is a potent yellow membrane-permeable fluorescent probe. LysoTracker Yellow HCK 123 is a weakly basic amine that selectively accumulates in cellular compartments with low luminal pH .

HY-D3251

LCP	Fluorescent Dye
LCP is a fluorescent probe applicable for subcellular localization. LCP responds to polarity changes in the cellular microenvironment via fluorescence resonance energy transfer, emitting blue fluorescence in low-polarity environments and red fluorescence in high-polarity environments. LCP enables dual-color visualization of dynamic changes in lysosomes and cytoplasmic membranes during drug-induced cell apoptosis, and monitors cell viability through localization and emission color changes. LCP can be used in cancer research .

LCP

Fluorescent Dye

LCP is a fluorescent probe applicable for subcellular localization. LCP responds to polarity changes in the cellular microenvironment via fluorescence resonance energy transfer, emitting blue fluorescence in low-polarity environments and red fluorescence in high-polarity environments. LCP enables dual-color visualization of dynamic changes in lysosomes and cytoplasmic membranes during drug-induced cell apoptosis, and monitors cell viability through localization and emission color changes. LCP can be used in cancer research .

Cat. No.	Product Name	Target	Research Area

HY-Y1080

N-Acetyl-R-leucine N-Acetyl-D-leucine	Amino Acid Derivatives Monocarboxylate Transporter	Endocrinology
N-Acetyl-R-leucine is an amino-protecting group N-substituted chiral amino acid. N-Acetyl-R-leucine is a PepT1 and MCT1 inhibitor with IC₅₀ of 0.74 and 11 mM, respectively. N-Acetyl-R-leucine can be used for LysoTracker signaling studies .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y1080

N-Acetyl-R-leucine N-Acetyl-D-leucine	Microorganisms Source Classification	Amino Acid Derivatives Monocarboxylate Transporter
N-Acetyl-R-leucine is an amino-protecting group N-substituted chiral amino acid. N-Acetyl-R-leucine is a PepT1 and MCT1 inhibitor with IC₅₀ of 0.74 and 11 mM, respectively. N-Acetyl-R-leucine can be used for LysoTracker signaling studies .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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LysoTracker

Inhibitors & Agonists

Fluorescent Dye

Peptides

NaturalProducts

Natural
Products