1 Result for "

MBM-55 (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MBM-55 (Standard)" in MCE Product Catalog:

Cat. No.: HY-101029R
CAS No.: 2083622-09-5
Research Areas:  

Cancer

MBM-55 (Standard) is the analytical standard of MBM-55 (HY-101029). This product is intended for research and analytical applications. MBM-55 is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 1 nM. MBM-55 shows a 20-fold or greater selectivity in most kinases with the exception of RSK1 (IC50=5.4 nM) and DYRK1a (IC50=6.5 nM). MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-55 shows antitumor activities, and no obvious toxicity to mice .
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