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Results for "

Menkes

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

4

Fluorescent Dyes

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12040
    Elesclomol
    110+ Cited Publications

    STA-4783

    		 Reactive Oxygen Species (ROS) Apoptosis Cuproptosis Cancer
    Elesclomol (STA-4783) is a potent copper ionophore and promotes copper-dependent cell death (cuproptosis). Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand. Elesclomol inhibits FDX1-mediated Fe-S cluster biosynthesis. Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis. Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research .
    Elesclomol
  • HY-12040S
    Elesclomol-d2

    STA-4783-d2

    		 Isotope-Labeled Compounds Reactive Oxygen Species (ROS) Apoptosis Cuproptosis Cancer
    Elesclomol-d2 (STA-4783-d2) is a deuterium labeled Elesclomol (HY-12040). Elesclomol (STA-4783) is a potent copper ionophore and promotes copper-dependent cell death (cuproptosis). Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand. Elesclomol inhibits FDX1-mediated Fe-S cluster biosynthesis. Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis. Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research .
    Elesclomol-d2
  • HY-W699990
    4-(1,2-Dihydroxyethyl)benzene-1,2-diol-d5

    		Isotope-Labeled Compounds Others
    4-(1,2-Dihydroxyethyl)benzene-1,2-diol-d5 is the deuterium labeled 4-(1,2-Dihydroxyethyl)benzene-1,2-diol (HY-W010066). 4-(1,2-Dihydroxyethyl)benzene-1,2-diol, a normal norepinephrine metabolite, is found to be associated with Menkes syndrome.
    4-(1,2-Dihydroxyethyl)benzene-1,2-diol-d5
  • HY-D3212
    Crisp-17

    		Fluorescent Dye Metabolic Disease
    Crisp-17 is a monovalent copper ion probe. Crisp-17 can be used to characterize cellular phenotypes associated with copper metabolism defects. Crisp-17 is applicable to research related to Menkes disease .
    Crisp-17
  • HY-D3215
    Lyso-Cu(II)

    		Fluorescent Dye Neurological Disease
    Lyso-Cu (II) is a lysosome-targeted divalent copper ion probe. Lyso-Cu (II) is applicable to the research of Wilson's disease, Menkes disease and Alzheimer's disease .
    Lyso-Cu(II)
  • HY-D3282
    CCF1

    		Fluorescent Dye Metabolic Disease
    CCF1 is a carbon-rhodol-based turn-on fluorescent copper sensor with high selectivity for Cu + over other biologically relevant metal ions. CCF1 detects changes in labile copper pools in living cells upon copper supplementation and/or depletion. CCF1 identifies elevations in labile copper pools in Atp7a -/ - fibroblast cell models. CCF1 can be used for the research of Menkes disease .
    CCF1
  • HY-D3207
    DHUCu-1

    		Fluorescent Dye Neurological Disease
    DHUCu-1 is a lysosome-targeted NIR divalent copper ion probe with high water solubility. DHUCu-1 serves as a tool for investigating the physiological functions of Cu 2+ and related diseases, such as Menke syndrome, Wilson's disease, and Alzheimer's disease .
    DHUCu-1

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