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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
Michael addition
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "Michael addition" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-166648
2
2 Cited Publications
Cat. No.: HY-166648A
DSPE-PEG-Maleimide ammonium (MW 2000) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG-Maleimide ammonium (MW 2000) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD. DSPE-PEG-Maleimide ammonium (MW 2000) is applicable to research on drug delivery .
Cat. No.: HY-W039953
CAS No.: 98924-81-3
Synonyms: N-azidoacetylglucosamine-tetraacylated
Target:
Research Areas:
Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-containing fully acetylated N-acetylglucosamine analog, a metabolic glycan marker, and also an inducer of S-glycosylation. Ac4GlcNAz can be taken up by bacteria, processed via endogenous carbohydrate biosynthesis pathways, and integrated into glycans by replacing natural monosaccharides. Under alkali promotion, Ac4GlcNAz undergoes β-elimination to form α,β-unsaturated aldehydes, which then bind to cysteine residues via Michael addition. Ac4GlcNAz can be integrated into glycoproteins. Ac4GlcNAz is applicable to research related to Helicobacter pylori infection .
Cat. No.: HY-P4566
CAS No.: 52899-09-9
Synonyms: Pro-Val
Target:
Research Areas:
Cat. No.: HY-W591476B
CAS No.: 134874-49-0
Synonyms: mPEG750-SH
Cat. No.: HY-16261A
CAS No.: 151038-96-9
Synonyms: (E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone
Target:
Research Areas:
MC-DOXHZN ((E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone) is an albumin-binding proagent of Doxorubicin (HY-15142A) (DNA topoisomerase II inhibitor), with acid-sensitive properties. MC-DOXHZN can be used to synthesize ADC .
Cat. No.: HY-W190755
CAS No.: 87135-00-0
Cat. No.: HY-W010354
CAS No.: 621-63-6
Target:
Cat. No.: HY-185048
Cat. No.: HY-150587
CAS No.: 3051838-54-8
Research Areas:
Anti-inflammatory agent 31 (enone 17) is a kind of andrographolide derivatives, is a anti-inflammatory agent. Anti-inflammatory agent 31 inhibits NF-κB activation by upstream blockade of PI3K/Akt and ERK1/2 MAPK activation. Anti-inflammatory agent 31 shows recovery effective of the intracellular GSH levels and protective effect on liver .
Cat. No.: HY-W190746
CAS No.: 123687-40-1
Cat. No.: HY-183387
CAS No.: 1348565-08-1
K11002 hydrobromide is a cysteine protease inhibitor. K11002 hydrobromide forms a covalent bond with the active site cysteine residue via Michael addition. K11002 hydrobromide inhibits the growth of Trypanosoma brucei. K11002 hydrobromide can be used in the research of African human trypanosomiasis (sleeping sickness) .
Cat. No.: HY-W697750
CAS No.: 497-03-0
Synonyms: Tiglaldehyde
Target:
Cat. No.: HY-W1052227
Cat. No.: HY-W1052492
Cat. No.: HY-W1052227A
Cat. No.: HY-W1052227B
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
