K11002 hydrobromide
K11002 hydrobromide is a cysteine protease inhibitor. K11002 hydrobromide forms a covalent bond with the active site cysteine residue via Michael addition. K11002 hydrobromide inhibits the growth of Trypanosoma brucei. K11002 hydrobromide can be used in the research of African human trypanosomiasis (sleeping sickness).
For research use only. We do not sell to patients.
- CAS No.: 1348565-08-1
- Formula: C31H36BrN3O5S
- Molecular Weight:642.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Hydrobromide form of K11002 (24 h potently inhibits the growth of bloodstream-form and anterior-circulation-form Trypanosoma brucei, with ED50 values of 4.1 nM and 7.0 nM respectively after 24 h of incubation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1348565-08-1
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Molecular Weight 642.60
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Formula C31H36BrN3O5S
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SMILES
O=S(/C=C/[C@H](CCC1=CC=CC=C1)NC([C@@H](NC(N2CCOCC2)=O)CC3=CC=CC=C3)=O)(C4=CC=CC=C4)=O.Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
K11002 hydrobromide Related Classifications
HY-183387 Related Classifications
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