3051838-54-8
Chemical Structure
Anti-inflammatory agent 31
- CAS No.: 3051838-54-8
- Formula:C19H30O3
- Molecular Weight:306.44
IUPAC Name: (E)-5-((1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)pent-3-en-2-one
InChIKey: SCARUZAAOKRPJG-UMAWGDKSSA-N
SMILES: CC(/C=C/C[C@@H]1C(CC[C@]2([H])[C@](C)(CO)[C@H](O)CC[C@@]12C)=C)=O
Biological Activity: Anti-inflammatory agent 31 (enone 17) is a kind of andrographolide derivatives, is a anti-inflammatory agent. Anti-inflammatory agent 31 inhibits NF-κB activation by upstream blockade of PI3K/Akt and ERK1/2 MAPK activation. Anti-inflammatory agent 31 shows recovery effective of the intracellular GSH levels and protective effect on liver[1].
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Anti-inflammatory agent 31 | Anti-inflammatory agent 31 (enone 17) is a kind of andrographolide derivatives, is a anti-inflammatory agent. Anti-inflammatory agent 31 inhibits NF-κB activation by upstream blockade of PI3K/Akt and ERK1/2 MAPK activation. Anti-inflammatory agent 31 shows recovery effective of the intracellular GSH levels and protective effect on liver. | |||||||||||||||||||||
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Keywords
