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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
NIR-II
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "NIR-II" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-133852
CAS No.: 1151666-58-8
1
1 Cited Publications
Cat. No.: HY-D1464
CAS No.: 1622250-38-7
1
1 Cited Publications
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FD-1080 free acid is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 free acid can be used for in vivo imaging .
1
Cat. No.: HY-W588722
CAS No.: 3024705-52-7
Cat. No.: HY-D1450
CAS No.: 155613-98-2
Synonyms: S01448
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IR-1048 is a nitroreductase (NTR)-responsive near-infrared fluorescence (NIR)/photoacoustic (PA) imaging probe and photothermal agent. IR-1048 is coupled with a nitroimidazole group to form IR-1048-MZ. IR-1048-MZ is catalytically reduced by NTR in a hypoxic environment, restoring strong near-infrared absorption and fluorescence emission (NIR II window), while activating the photothermal effect. IR-1048 relies on NTR-mediated electron transfer to relieve intramolecular fluorescence quenching, achieving specific imaging and photothermal ablation of tumor hypoxic areas. IR-1048 is mainly used for high-contrast NIR II/photoacoustic imaging and photothermal therapy research and tumor diagnosis of the tumor hypoxic microenvironment .
Cat. No.: HY-D2999
CAS No.: 2996066-33-0
Cat. No.: HY-151109
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IR-990 is an activatable NIR-II fluorescent probe with an acceptor-π-acceptor (A-π-A) skeleton for real-time detection of H2O2 in vivo. IR-990 is a powerful diagnosis of agent-induced liver injury (DILI) .
Cat. No.: HY-142523
CAS No.: 2803681-14-1
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H7 is a second near-infrared (NIR-II) fluorophore .
Cat. No.: HY-149298
CAS No.: 2946600-14-0
PSMA-IN-2 is an inhibitor of PSMA with a Ki value of 1.07 nM. PSMA-IN-2 displays favorable in vivo NIR imaging (λEM = 1088 nm, λex = 808 nm), and can be used for NIRII image-guided tumor resection surgery in PSMA-positive tumor-bearing mice .
Cat. No.: HY-155003
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TPEQM-DMA is a NIR-II photosensitizer. TPEQM-DMA accumulates in cancerous mitochondria, and inhibits cancer cell growth. TPEQM-DMA has potent type-I phototherapeutic efficacy to overcome the intrinsic pitfalls of PDT in combating hypoxic tumors .
Cat. No.: HY-149765
CAS No.: 2481214-36-0
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Bone-1064 is a EuK-based PSMA tetramer bone probe for high-contrast visualization of bone in surrounding tissue. Bone-1064 specifically binds hydroxyapatite in bone tissue and can be used for NIR-II fluorescence imaging in animal models .
Cat. No.: HY-D3113
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BF6 is a blood-brain barrier permeable NIR probe. BF6 can diffuse from intracranial blood vessels into brain tissue, enabling visualization of brain structures and differentiation between glioblastoma (GBM) and normal tissues. The absorption peaks of BF6 in DMSO and FBS range from 727 to 859 nm, with a broad fluorescence emission band spanning 800 to 1400 nm; its emission wavelength falls within the NIR-II region (800-1400 nm) .
Cat. No.: HY-D3136
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MC-PSE is a fluorescent probe that can be used for glutathione (GSH) detection, NIR-II fluorescence imaging and ratiometric photoacoustic imaging. MC-PSE spontaneously forms J-aggregates in aqueous solution through π-π stacking, and its phenylselenyl group acts as a fluorescence quencher and GSH recognition receptor, thereby eliminating intrinsic fluorescence and generating a maximum absorption peak at 1000 nm. The excitation/emission wavelengths of MC-PSE are Ex = 808 nm and Em = 940 nm. MC-PSE can be applied in tumor-related research .
Cat. No.: HY-D2996
CAS No.: 3030491-95-0
Cat. No.: HY-D3432
Cat. No.: HY-D3398
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Research Areas:
FlavAc is a fluorescent dye (with an excitation wavelength of 980 nm) for real-time in vivo imaging of lipid metabolism disorders, including early fatty liver disease and atherosclerotic plaques. FlavAc specifically integrates into endogenous lipoproteins, primarily low-density lipoprotein (LDL), and shows no brightness enhancement when bound to albumin. FlavAc forms aggregates in aqueous solutions, leading to fluorescence quenching; however, when integrated into lipoproteins, such aggregation decreases, forming stable fluorescent complexes with enhanced brightness. FlavAc can selectively illuminate LDL upon laser irradiation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
