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Results for "

PEG2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (90) ADC Payload (1) Anaplastic lymphoma kinase (ALK) (1) Antibiotic (1) Antibody-Drug Conjugates (ADCs) (3) Antibody-Oligonucleotide Conjugates (AOCs) (1) Apoptosis (24) Asialoglycoprotein Receptor (ASGPR) (1) Aurora Kinase (2) Autophagy (23) Biochemical Assay Reagents (49) Bombesin Receptor (1) c-Met/HGFR (2) CCR (1) CDK (2) Complement System (2) DNA Alkylator/Crosslinker (2) DNA/RNA Synthesis (2) Drug Derivative (1) Drug Intermediate (2) Drug Isomer (1) Drug-Linker Conjugates for ADC (14) E3 Ligase Ligand-Linker Conjugates (75) EGFR (3) Environmental Pollutants (1) Epigenetic Reader Domain (1) Ferroptosis (1) Fluorescent Dye (19) Glutaminase (1) Glutathione Peroxidase (1) HyT (1) Integrin (1) Isotope-Labeled Compounds (1) Ligands for E3 Ligase (4) Ligands for Target Protein for PROTAC (2) LIM Kinase (LIMK) (1) Liposome (5) LYTACs (1) Microtubule/Tubulin (3) N-myristoyltransferase (1) Phosphoramidites (2) Polo-like Kinase (PLK) (1) PROTAC Linkers (335) PROTACs (7) Radionuclide-Drug Conjugates (RDCs) (1) Reactive Oxygen Species (ROS) (1) Reference Standards (8) ROS Kinase (1) RXFP Receptor (1) Small Interfering RNA (siRNA) (1) STING (3) Target Protein Ligand-Linker Conjugates (2) Thyroid Hormone Receptor (1) Toll-like Receptor (TLR) (2) Topoisomerase (2) Wee1 (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (503) Cardiovascular Disease (1) Endocrinology (1) Infection (2) Inflammation/Immunology (10) Metabolic Disease (1)
Click Chemistry:	ADC Synthesis (27) Labeling and Fluorescence Imaging (12) TCO (15) DBCO (24) PROTAC Synthesis (94) BCN (18) Azide (73) Tetrazine (2) Alkynes (39)
Oligonucleotides:	Pegylated Lipids (3) Emulsifiers (1) Mouse Pre-designed siRNA Sets (1) Cationic Lipids (2) Other Phosphoramidite (2) Phosphoramidites (2) siRNAs (1)

602

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

171

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-131872

*Pomalidomide-PEG2-COOH* Pomalidomide 4'-PEG2-acid	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG2-COOH (Pomalidomide 4'-PEG2-acid) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology .

HY-128870

*Mal-PEG2-VCP-Eribulin*	Drug-Linker Conjugates for ADC	Cancer
Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin (HY-13442). Eribulin is a mechanistically unique microtubule inhibitor and Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules. Mal-PEG2-VCP-Eribulin is an Eribulin-based agent for antibody conjugates ^[2] .

HY-W051634

*Propargyl-PEG2-amine*	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs ^[2]. Propargyl-PEG2-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-148865

*Puromycin-bis(PEG2-amide)-Biotin* 1 Publications Verification	Biochemical Assay Reagents	Others
Puromycin-bis (PEG2-amide)-Biotin (Compound 3P) is a binding molecule. Puromycin-bis (PEG2-amide)-Biotin binds to ribosome-RNA complexes within single cells. Puromycin-bis (PEG2-amide)-Biotin is used for single-cell translatome sequencing .

HY-130442

*Mal-PEG2-acid*	ADC Linker PROTAC Linkers	Cancer
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule . Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs.

HY-113697

*Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD* 2 Publications Verification Mal-PEG2-AZD	PROTAC Linkers	Cancer
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (Mal-PEG2-AZD) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W008429

*m-PEG2-Amine*	ADC Linker PROTAC Linkers	Cancer
m-PEG2-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG2-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W006445

*N-Boc-PEG2-bromide*	ADC Linker PROTAC Linkers	Cancer
N-Boc-PEG2-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W096164

*Propargyl-PEG2-bromide*	PROTAC Linkers	Cancer
Propargyl-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG2-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-112559

*Bis-PEG2-acid*	PROTAC Linkers	Cancer
Bis-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .

HY-136133

*NHS-PEG2-SS-PEG2-NHS*	ADC Linker	Cancer
NHS-PEG2-SS-PEG2-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-130541

*Propargyl-PEG2-OH*	PROTAC Linkers	Cancer
Propargyl-PEG2-OH is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl (HY-126458) . Propargyl-PEG2-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-156748

*MC-PEG2-VA-PAB-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
MC-PEG2-VA-PAB-Exatecan (Compound DL-18) is a Drug-Linker Conjugates for ADC. MC-PEG2-VA-PAB-Exatecan consists of Exatecan (HY-13631) and a linker. MC-PEG2-VA-PAB-Exatecan can be used for synthesis of ADCs .

HY-126958

*Biotin-PEG2-acid*	PROTAC Linkers ADC Linker	Inflammation/Immunology Cancer
Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-118764

*Propargyl-PEG2-acid*	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG2-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130162

*Tos-PEG2-O-Propargyl*	PROTAC Linkers	Cancer
Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl (HY-126458) . Tos-PEG2-O-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-114995

*Tr-PEG2-OH*	PROTAC Linkers ADC Linker	Inflammation/Immunology Cancer
Tr-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tr-PEG2-OH is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) ^[2].

HY-138524

*Thiol-PEG2-acid*	PROTAC Linkers	Cancer
Thiol-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W067061

*Hydroxy-PEG2-(CH2)2-Boc*	ADC Linker PROTAC Linkers	Cancer
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196) . Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.

HY-118808

*Propargyl-PEG2-NHBoc*	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG2-NHBoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG2-NHBoc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130328

NH-bis-PEG2	ADC Linker PROTAC Linkers	Cancer
NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH-bis-PEG2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-W190932

*TAMRA-PEG2-Maleimide*	Fluorescent Dye	Others
TAMRA-PEG2-Maleimide is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.

HY-W105666

PEG2-Dichloride Triglycol dichloride	PROTAC Linkers	Cancer
PEG2-Dichloride (Triglycol dichloride) is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-155327B

*Cy3-PEG2-endo-BCN bromide*	Fluorescent Dye	Others
Cy3-PEG2-endo-BCN bromide is the bromide salt form of Cy3-PEG2-endo-BCN (HY-155327). Cy3-PEG2-endo-BCN bromide is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN bromide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts .

HY-138734

*Propargyl-PEG2-NHS ester*	PROTAC Linkers	Cancer
Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-43055

*Cl-PEG2-acid*	PROTAC Linkers	Cancer
Cl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-124380

*Hydroxy-PEG2-acid*	PROTAC Linkers	Cancer
Hydroxy-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-164181

*Fmoc-protected DMT-Dt PEG2* NH2 amidite**	DNA/RNA Synthesis Phosphoramidites	Cancer
Fmoc-protected DMT-Dt PEG2 NH2 amidite is a phosphoramidite monomer.

HY-W047691

*Allyl-PEG2-OH* Acryloyl-PEG2-OH	Biochemical Assay Reagents	Others
Allyl-PEG2-OH (Acryloyl-PEG2-OH) is a PEG derivative that can be used for drug delivery and other research .

HY-P3502B

*Zilucoplan (PEG2)*	Complement System	Inflammation/Immunology
Zilucoplan (PEG2) is a Zilucoplan (HY-P3502) derivative, where the linker section replaces PEG24 by PEG2. Zilucoplan is a potent complement component 5 (C5) inhibitor .

HY-161129

*Lenalidomide 4'-PEG2-amine dihydrochloride*	E3 Ligase Ligand-Linker Conjugates	Cancer
Lenalidomide 4'-PEG2-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG2-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC .

HY-139543

*Thalidomide-5-PEG2-Cl*	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-5-PEG2-Cl is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-PEG2-Cl can be connected to the ligand for protein by a linker to form PROTACs .

HY-130231

*m-PEG2-acid*	PROTAC Linkers	Cancer
m-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-148549

*MC-PEG2-Boc*	Biochemical Assay Reagents	Others
MC-PEG2-Boc (compound 3b) is a Boc-protected Maleimide. MC-PEG2-Boc can be used for the preparation of maleimide linker .

HY-W250654

PEG2-MeN-Boc	PROTAC Linkers	Cancer
PEG2-MeN-Boc is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W025724

PEG2-NH-Cbz	PROTAC Linkers	Cancer
PEG2-NH-Cbz is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-42745

*m-PEG2-Tos*	ADC Linker PROTAC Linkers	Cancer
m-PEG2-Tos is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG2-Tos is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-W190842

*m-PEG2-NHS ester*	Biochemical Assay Reagents	Others
m-PEG2-NHS ester is a PEG linker containing an NHS ester. The NHS ester of m-PEG2-NHS ester is used to label primary amines (-NH₂) of proteins, amine-modified oligonucleotides and other amine-containing molecules. The hydrophilic PEG spacer effectively improves solubility in aqueous media. m-PEG2-NHS ester can be used in studies related to bioconjugation with ADC, proteins, peptides and other molecules .

HY-W022204

*Thiol-PEG2-thiol*	PROTAC Linkers	Cancer
Thiol-PEG2-thiol is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-155322

*Cy3-PEG2-TCO*	Fluorescent Dye	Others
Cy3-PEG2-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

HY-133498

*HyNic-PEG2-DBCO*	PROTAC Linkers	Cancer
HyNic-PEG2-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . HyNic-PEG2-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140283

*DBCO-PEG2-amine*	PROTAC Linkers	Cancer
DBCO-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG2-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140155

*Methylamino-PEG2-Boc* Methylamino-PEG2-t-butyl ester	PROTAC Linkers	Cancer
Methylamino-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-138476

Benzyl-PEG2-ethoxyethane-PEG2	PROTAC Linkers	Cancer
Benzyl-PEG2-ethoxyethane-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W762473

*Boc-NH-PEG2-CONH-PEG2-COOH*	PROTAC Linkers	Cancer
Boc-NH-PEG2-CONH-PEG2-COOH is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-167759

*Pomalidomide-PEG2-acetic acid* Pomalidomide-PEG2-CH2COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG2-acetic acid (Pomalidomide-PEG2-CH2COOH) is the conjugate composed of a E3 ligase ligand and a linker. Pomalidomide-PEG2-acetic acid can be used for PROTAC synthesis .

HY-140085

*N-(PEG2-C2-acid)-N-bis(PEG2-propargyl)*	PROTAC Linkers	Cancer
N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W142428

PEG 2 lauryl ether Diethylene glycol monododecyl ether	Biochemical Assay Reagents	Others
PEG 2 lauryl ether can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-133191

Bis-propargyl-PEG2	PROTAC Linkers	Infection Cancer
Bis-propargyl-PEG2 is a *PEG*-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG2 is used for the synthesis of demethylvancomycin dimers ^[2]. Bis-propargyl-PEG2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W096116

PEG2-Cl	PROTAC Linkers	Cancer
PEG2-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Cat. No.	Product Name	Type

HY-W190932

*TAMRA-PEG2-Maleimide*	Fluorescent Dye
TAMRA-PEG2-Maleimide is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.

HY-D2527

*Biotin-PEG4-amide-PEG2-C6-Cl*	Fluorescent Dye
Biotin-PEG4-amide-PEG2-C6-Cl is a biotinylated PEG4-amide-PEG2-C6-Cl.

HY-155322

*Cy3-PEG2-TCO*	Fluorescent Dye
Cy3-PEG2-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

HY-D2142

*Cy5-PEG2-TCO*	Fluorescent Dye
Cy5-PEG2-TCO is a fluorescent dye that reacts with tetrazines. Cy5-PEG2-TCO contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.

HY-149620

*Cy5-PEG2-exo-BCN*	Fluorescent Dye
Cy5-PEG2-exo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-155327

*Cy3-PEG2-endo-BCN*	Fluorescent Dye
Cy3-PEG2-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2111

TAMRA-PEG2-N3

Fluorescent Dye

TAMRA-PEG2-N3 is a TAMRA (HY-135640) dye derivative containing 4 PEG units. TAMRA-PEG2-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N₃). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-177414

BB-1701

Fluorescent Dye

BB-1701 is an anti-HER2 antibody-drug conjugate (ADC). BB-1701 is composed of a humanized anti-HER2 antibody (Trastuzumab) (HY-P9907), a linker (Mal-PEG2-VCP), a microtubule inhibitor (Eribulin) (HY-13442), and the drug-linker conjugate for ADC is Mal-PEG2-VCP-Eribulin (HY-128870). BB-1701 has a potent cytotoxicity and bystander effects on tumors with heterogeneous target expression. BB-1701 significantly induces immunogenic cell death and the activation of the immune .

HY-156303

*Coumarin-PEG2-TCO*	Fluorescent Dye
Coumarin-PEG2-TCO is a dye derivative of Coumarin (HY-N0709) containing 2 PEG units. Coumarin-PEG2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-D2122

*Cy3-PEG2-SCO*	Fluorescent Dye
Cy3-PEG2-SCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-SCO carries a SCO group that can be covalently bound to an amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.

HY-D2153

*Cy5-PEG2-SCO*	Fluorescent Dye
Cy5-PEG2-SCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-SCO has a SCO group that can be covalently bonded to the amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.

HY-D1867

Sulfo-Cy3-PEG2-TCO disodium

Fluorescent Dye

Sulfo-Cy3-PEG2-TCO disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate and TCO groups. The TCO groups of Sulfo-Cy3-PEG2-TCO disodium react with tetrazine functional groups in highly specific click chemistry to form covalent bonds. Thus, Sulfo-Cy3-PEG2-TCO disodium can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.

HY-D2098

*TAMRA-PEG2-NH2*	Fluorescent Dye
TAMRA-PEG2-NH2 is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.

HY-155325

*Cy3-PEG2-TCO4*	Fluorescent Dye
Cy3-PEG2-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

HY-D2145

*Cy5-PEG2-TCO4*	Fluorescent Dye
Cy5-PEG2-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-156302

*Coumarin-PEG2-endoBCN*	Fluorescent Dye
Coumarin-PEG2-endoBCN is a fluorescent dye containing a coumarin fluorophore and can be used as a click chemistry reagent .

HY-D2136

*Cy3-PEG2-Azide*	Fluorescent Dye
Cy3-PEG2-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 2 PEG units. Cy3-PEG2-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-155327A

*Cy3-PEG2-exo-BCN*	Fluorescent Dye
Cy3-PEG2-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2099

*Coumarin-PEG2-SCO*	Fluorescent Dye
Coumarin-PEG2-SCO, a Coumarin (HY-N0709) deravitive, is a fluorescent dye, and can be used for labeling of small molecules and biomolecules .

HY-D1312

Pyrene azide 2	Fluorescent Dye
Pyrene azide 2 is a compound derived from pyreneacetic acid, connecting a fluorescent pyrene molecule by a PEG2 linker. The PEG units improve the water solubility of the compound.

Cat. No.	Product Name	Type

HY-W047691

*Allyl-PEG2-OH* Acryloyl-PEG2-OH	Biochemical Assay Reagents
Allyl-PEG2-OH (Acryloyl-PEG2-OH) is a PEG derivative that can be used for drug delivery and other research .

HY-W588715A

*Acid-PEG2-NHS ester*	Biochemical Assay Reagents
Acid-PEG2-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.

HY-174947

*DPPE-PEG2-mal*	Biochemical Assay Reagents
DPPE-PEG2-mal is an amphiphilic phospholipid-modified polymer that can be used to prepare lipid nanoparticles or liposomes for targeted drug delivery applications .

HY-W096120B

Azide-PEG2-Desthiobiotin

Biochemical Assay Reagents

Azide-PEG2-Desthiobiotin is a PEG derivative consisting of desthiobiotin, 2 PEG units, and an azide group. Biotin can form a stable non-covalent bond with streptavidin. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .

HY-W440681

C13-112-tri-tail	Biochemical Assay Reagents
C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).

HY-W440683

C13-112-tetra-tail	Biochemical Assay Reagents
C13-112-tetra-tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tetra-tail can be formulated into a lipid nanoparticle (LNP).

HY-29501

*Thiol-PEG2-NH2* SH-PEG2-NH2	Biochemical Assay Reagents
Thiol-PEG2-NH2 (SH-PEG2-NH2) is a PEG derivative consisting of a thiol (-SH), 2 PEG units, and NH2. Thiol is a highly reactive chemical group that can react specifically with a variety of molecules to form stable covalent bonds.

HY-W190745A

*DNP-PEG2-NHS ester*	Biochemical Assay Reagents
DNP-PEG2-NHS ester is a PEG derivative that contains DNP (2,4-dinitroaniline), two PEG units, and NHS ester. NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). DNP-PEG2-NHS ester can be used for drug delivery.

HY-W190891

*NH2-PEG2-COOMe*	Biochemical Assay Reagents
NH2-PEG2-COOMe is a biochemical reagent that can be used in drug delivery research .

HY-W190791

*DNP-PEG2-NH2*	Biochemical Assay Reagents
DNP-PEG2-NH2 is a PEG derivative that can be used for drug delivery research.

HY-140617A

DNP-PEG2-azide

Biochemical Assay Reagents

DNP-PEG2-azide is a PEG derivative that can be used for drug delivery and other research. DNP-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-W838953

*NHBoc-PEG2-NH-CH2COOH*	Biochemical Assay Reagents
NHBoc-PEG2-NH-CH2COOH is a PEG derivative that can be used for drug delivery and other research.

HY-W793100

*Endo-BCN-PEG2-Biotin*	Biochemical Assay Reagents
Endo-BCN-PEG2-Biotin is a PEG linker containing a BCN group and a terminal carboxylic acid. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

Cat. No.	Product Name	Target	Research Area

HY-P10392AF

fStAx-35R TFA	Wnt β-catenin	Cancer
fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .

HY-P10909

Canvuparatide MBX 2109	Thyroid Hormone Receptor	Endocrinology
Canvuparatide (MBX 2109) is a prodrug for parathyroid hormone (PTH) peptide that releases the bioactive PTH[1-32] peptide agonist that retains a fatty acylated lysine (Lys33) at the C-terminus, thereby extending the halflife of Canvuparatide. Canvuparatide can be used for the symptoms of hypoparathyroidism such as hypocalcemia and hyperphosphatemia .

HY-P10896

NOTA-P2-RM26	Bombesin Receptor	Cancer
NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with ¹¹¹In and ⁶⁸Ga for prostate cancer imaging studies using PET and SPECT/CT .

HY-P10946

*FAP targeting peptide-PEG2* conjugate**	Radionuclide-Drug Conjugates (RDCs)	Cancer
FAP targeting peptide-PEG2 conjugate (Example A1) is the peptide (HY-P10945) and linker conjugate of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand ^[2].

HY-169232

PCC16 chloride	PROTACs	Cancer
PCC16 chloride is a CRBN-based cp-PCC with an IC₅₀ value of 102 nM for the degradation of DHHC3. PCC16 chloride has antitumor activity. (Target protein ligand: HY-169235, linker: HY-169236, E3 ligase ligand: HY-10984) .

HY-157737A

*GVSKYG-PEG2-azide hydrochloride*	PROTAC Linkers ADC Linker	Cancer
GVSKYG-PEG2-azide (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-157737

*GVSKYG-PEG2-azide TFA*	PROTAC Linkers ADC Linker	Cancer
GVSKYG-PEG2-azide (TFA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-P11625

R9-13	RXFP Receptor	Cardiovascular Disease
R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .

HY-P11596

NOTA-Asp2-αvβ6L	Integrin	Cancer
NOTA-Asp2-αvβ6L is an integrin αvβ6 binder with selective accumulation in αvβ6-positive pancreatic cancer cells and tumors. NOTA-Asp2-αvβ6L can be used as a PET/CT tracer for imaging pancreatic ductal adenocarcinoma (PDAC) .

HY-P11830

UDA-6

HY-P3252AS

Pegcetacoplan-13C3,15N TFA	Isotope-Labeled Compounds Complement System	Inflammation/Immunology
Pegcetacoplan- ¹³C₃, ¹⁵N TFA is the ¹³C- and ¹⁵N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16321

*C18:0 DG-PEG2K-triGalNAc*	Lipid	Biochemical Assay Reagents
C18:0 DG-PEG2K-triGalNAc is a functionalized PEG lipid that consists of a C18:0 DG unit conjugated to a triGalNAc. C18:0 DG-PEG2K-triGalNAc can be used to prepare lipid nanoparticles for drug delivery.

HY-N15973

*DSPE PEG2k-OH ammonium*	Lipid	Biochemical Assay Reagents
DSPE PEG2k-OH ammonium is a hydroxyl-terminated PEGylated phospholipid. The hydrophobic tail allows for the encapsulation and aggregation of other hydrophobic drugs, and the hydroxyl terminus is suitable for further reactions. DSPE PEG2k-OH ammonium can be used to prepare liposomes or lipid nanoparticles .

HY-N15903

*DSPE-PEG2k-tri Mannose ammonium*	Lipid	Biochemical Assay Reagents
DSPE-PEG2k-tri Mannose ammonium is a trimannose-DSPE-conjugated PEG derivative that can be used to synthesize lipid nanoparticles for drug delivery.

HY-N16323

*DSPE-PEG2K-triGalNAc (II) ammonium*	Lipid	Biochemical Assay Reagents
DSPE-PEG2K-triGalNAc (II) ammonium is a functionalized PEG lipid that consists of a DSPE unit conjugated to a triGalNAc. DSPE-PEG2K-triGalNAc (II) ammonium can be used to prepare lipid nanoparticles for drug delivery.

HY-N15951

*C16 Ceramide-suc-PEG2K-maleimide*	Lipid	Biochemical Assay Reagents
C16 Ceramide-suc-PEG2K-maleimide is functionalized PEG lipid that can be used to synthesize lipid nanoparticles for drug delivery.

Cat. No.	Product Name	Chemical Structure

HY-P3252AS

Pegcetacoplan-13C3,15N TFA

Pegcetacoplan- ¹³C₃, ¹⁵N TFA is the ¹³C- and ¹⁵N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).

Cat. No.	Product Name		Classification

HY-157950

*DSPE-PEG2000-triGalNAc ammonium*		Pegylated Lipids
DSPE-PEG2K-triGalNAc ammonium is a polar lipid composed of DSPE and tri-N-acetylgalactosamine that can be used to construct liposomes target to asialoglycoprotein receptor (ASGPR).

HY-N15956

*DMG-PEG(2k)-DBCO*		Pegylated Lipids
DMG-PEG(2k)-DBCO is a Clickable PEG lipid containing a DBCO group. DSPE-PEG8-DBCO can be used to prepare lipid nanoparticles for drug delivery.

HY-164181

*Fmoc-protected DMT-Dt PEG2* NH2 amidite**		Phosphoramidites Other Phosphoramidite
Fmoc-protected DMT-Dt PEG2 NH2 amidite is a phosphoramidite monomer.

HY-W142428

PEG 2 lauryl ether Diethylene glycol monododecyl ether		Emulsifiers
PEG 2 lauryl ether can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-W440681

C13-112-tri-tail		Cationic Lipids
C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).

HY-W440683

C13-112-tetra-tail		Cationic Lipids
C13-112-tetra-tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tetra-tail can be formulated into a lipid nanoparticle (LNP).

HY-RS16571

Igf2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Igf2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Igf2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-171728

*Azide-PEG2-amide-C14-COOH*		Pegylated Lipids
Azide-PEG2-amide-C14-COOH (Compound LP-379-p) is a lipid-containing compound. Azide-PEG2-amide-C14-COOH facilitates the delivery of oligonucleotide-based reagents to certain cell types or adipose tissue .

HY-402409

*5'-Amino-modifier C2-PEG2-TFA*		Phosphoramidites Other Phosphoramidite
2-Cyanoethyl (2-(2-(2-(2,2,2-trifluoroacetamido)ethoxy)ethoxy)ethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

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