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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
PHB
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "PHB" in MCE Product Catalog:
3
3 Cited Publications
Fluorizoline selectively and directly binds to prohibitin 1 (PHB1) and 2 (PHB2), and induces apoptosis. Fluorizoline reduces chronic lymphocytic leukemia (CLL) cell viability through the upregulation of NOXA and BIM. Fluorizoline exerts antitumor action in a p53-independent manner .
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1 Cited Publications
JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity .
Cat. No.: HY-W008235
CAS No.: 84000-07-7
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Fmoc-N-Me-Ala-OH is an Fmoc-protected N-methyl-L-alanine and also a building block for solid-phase peptide synthesis. As a building block, Fmoc-N-Me-Ala-OH is used to synthesize peptidomimetic antagonists of XIAP BIR3 derived from Smac/DIABLO .
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YL-939 is a potent ferroptosis inhibitor. YL-939 inhibits ferroptosis by targeting the PHB2/ferritin/iron axis .
Cat. No.: HY-124484
CAS No.: 2234271-86-2
JI130 (JI051 derivative ) is a stabilizer for the Hes1-PHB2 interaction. JI130 inhibits the ability of Hes1 to repress transcription. JI130 significantly reduces the tumor growth in a murine pancreatic tumor model and has the potential for managing pancreatic cancer .
Cat. No.: HY-RS16807
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Phb2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Phb2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-162904
CAS No.: 2198977-68-1
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BPU17 binds to PHB1 and causes mild defects in mitochondrial function by defects in the PHB1-PHB2 interaction. This impairment inhibits the SRF/CArG-box-dependent transcription, resulting in the suppression of epithelial-mesenchymal transition (EMT) of retinal pigment epithelial cells (RPEs). BPU17 exhibits antifibrotic activity in vivo. BPU17 is promising for research of anti-neovascular age-related macular degeneration (nAMD) agent .
Cat. No.: HY-RS10407
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PHB1 Human Pre-designed siRNA Set A contains three designed siRNAs for PHB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-141475
CAS No.: 102029-52-7
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Cat. No.: HY-RS10408
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PHB2 Human Pre-designed siRNA Set A contains three designed siRNAs for PHB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23247
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Phb2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Phb2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23750
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Phb1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Phb1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17295
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Phb1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Phb1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-184779
CAS No.: 29435-48-1
Synonyms: PHB
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Poly[(R)-3-hydroxybutyrate] (PHB) is a polyhydroxyalkanoate polymer with biocompatibility and processability. Poly[(R)-3-hydroxybutyrate] can be used to prepare drug delivery nanoparticles and tissue engineering scaffolds. Poly[(R)-3-hydroxybutyrate] is applicable to research related to drug delivery, tissue engineering and wound dressing materials .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
