2234281-75-3
2234281-75-3
Chemical Structure
JI051
- CAS No.: 2234281-75-3
- Formula:C22H24N2O3
- Molecular Weight:364.44
IUPAC Name: (E)-N-(2-ethoxyphenethyl)-3-(7-methoxy-1H-indol-3-yl)acrylamide
InChIKey: CQZPBIZGVIRKOC-VAWYXSNFSA-N
SMILES: O=C(NCCC1=CC=CC=C1OCC)/C=C/C2=CNC3=C2C=CC=C3OC
Biological Activity: JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JI051 | 98.0% | JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity. | ||||||||||||||||||||
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References
Keywords
