2234281-75-3

JI051 Chemical Structure
2234281-75-3

Chemical Structure

JI051

  • CAS No.: 2234281-75-3
  • Formula:C22H24N2O3
  • Molecular Weight:364.44

IUPAC Name: (E)-N-(2-ethoxyphenethyl)-3-(7-methoxy-1H-indol-3-yl)acrylamide

InChIKey: CQZPBIZGVIRKOC-VAWYXSNFSA-N

SMILES: O=C(NCCC1=CC=CC=C1OCC)/C=C/C2=CNC3=C2C=CC=C3OC

Biological Activity: JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity[1].

Cat. No. Product Name Purity Description Pricing
HY-117113 		JI051 98.0% JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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