2 Results for "

PI3K/Akt/mTOR cascade

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PI3K/Akt/mTOR cascade" in MCE Product Catalog:

Cat. No.: HY-P990610

Target:  

Akt mTOR PI3K

Research Areas:  

Cancer

KHK-2898 is a monoclonal antibody targeting CD98, which binds to the extracellular domain of CD98 on the tumor cell membrane in a non-covalent antigen-specific mode. KHK-2898 can disrupt the heterodimeric complex formed by CD98 with LAT1 and xCT light chains, reduce the amino acid uptake capacity of tumor cells, block the PI3K/AKT/mTOR proliferative signaling cascade, and mediate antibody-dependent cytotoxicity. KHK-2898 can be used for cancer-related research. The isotype control of KHK-2898 can be found in Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-116191
CAS No.: 1309087-83-9
Target:  

PI3K mTOR

Research Areas:  

Cancer

WJD008 is a potent dual phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor with antiproliferative and anticlonogenic activity in tumor cells and transformed cells with PIK3CA mutant. WJD008 inhibits kinase activity of PI3K α and mTOR and abrogates insulin-like growth factor-I-activated PI3K-Akt-mTOR signaling cascade. WJD008 is promising for research of cancers .
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