7 Results for "

RM-1

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "RM-1" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-12486
CAS No.: 135415-73-5
Purity:  99.40%
Synonyms: 10,11-(Methylenedioxy)-20(S)-camptothecin
Target:  

Survivin Apoptosis IAP

Research Areas:  

Cancer

FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin (HY-16560) analogue, is a potent and orally active survivin inhibitor. FL118 binds to oncoprotein DDX5 (p68) to dephosphorylates and degrades DDX5. FL118 can be used for the research of cancer [1] .
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Cat. No.: HY-121793
CAS No.: 548-08-3
Purity:  99.61%
Synonyms: (-)-Roemerine
Roemerine is an alkaloid that has been identified from the leaves of Fibraurea recisa Pierre. Roemerine exhibits antibacterial, anticancer, and antidepressant activities, can reverse the multidrug resistance phenotype in cultured cells, and exerts antibacterial effects by regulating the cAMP signaling pathway. Additionally, Roemerine influences neuronal activity by increasing BDNF protein expression and modulating the serotonergic and glutamatergic systems. Roemerine holds promise for research in the fields of cancer, infections, and neurological diseases [1] .
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Cat. No.: HY-P990265
Anti-Mouse CD69 Antibody (CD69.2.2) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to mouse CD69. Anti-Mouse CD69 Antibody (CD69.2.2) causes CD69 to be internalized but does not deplete CD69 + cells. Anti-Mouse CD69 Antibody (CD69.2.2) can be used for the researches of cancer, infection, inflammation and immunology, such as RMA-S tumor, arthritis and vaccinia virus (VACV) infection [1] .
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Cat. No.: HY-P991243

Target:  

EGFR Akt

Research Areas:  

Cancer

MP-RM-1 is an antibody-based, non-competitive ErbB-3 inhibitor with a Kd value of 32.7 nM. MP-RM-1 inhibits both ligand-dependent and ligand-independent ErbB-3 activation, blocks ErbB-2/ErbB-3 heterodimerization, induces ErbB-3 internalization and degradation, and suppresses the phosphorylation of downstream Akt. MP-RM-1 exerts its antagonistic effect through a non-competitive mechanism. MP-RM-1 inhibits tumor growth in melanoma and prostate cancer xenograft models in nude mice and reduces the proliferative activity of tumor cells [1].
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Cat. No.: HY-162264
CAS No.: 3032401-72-9
Tubulin polymerization/V-ATPase-IN-1 (compound F10) is a Tubulin polymerization/V-ATPase inhibitor. Tubulin polymerization/V-ATPase-IN-1 shows robust antiproliferation activity against four human cancer cell lines, and exerts antiproliferative activity by inhibiting tubulin and V-ATPase. Tubulin polymerization/V-ATPase-IN-1 induces immunogenic cell death in addition to apoptosis, and inhibits tumor growth in an RM-1 homograft model with enhanced T lymphocyte infiltration [1].
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Cat. No.: HY-RS14548
Research Areas:  

Others

Tiparp Rat Pre-designed siRNA Set A contains three designed siRNAs for Tiparp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P703622
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TIPARP; PARP-1; TCDD Inducible Poly(ADP-Ribose) Polymerase; DDF1; ARTD14; RM1; PARP7; TCDD-Inducible Poly(ADP-Ribose) Polymerase, IsofoRM CRA_b; PARP-7; TCDD-Inducible Poly(ADP-Ribose) Polymerase, IsofoRM CRA_c; PART14; TCDD-Inducible Poly [ADP-Ribose] Po
Species:  
Source:  
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