9 Results for "

Reboxetine

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Reboxetine" in MCE Product Catalog:

Cat. No.: HY-14560
CAS No.: 71620-89-8
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

Reboxetine is an orally active, potent and selective noradrenaline uptake blocker. Reboxetine can be used for antidepressant research .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-14560C
CAS No.: 98769-84-7
Purity:  99.87%
Synonyms: FCE20124 mesylate; PNU155950E mesylate
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

Reboxetine mesylate (FCE20124 mesylate) is a potent, selective, and specific noradrenaline reuptake inhibitor (NARI) for the research of depression. Reboxetine mesylate inhibits the uptake of norepinephrine, with a Ki of 8 nM .
loading...
    loading...
Cat. No.: HY-14790
CAS No.: 98819-76-2
Synonyms: (S,S)-(+)-Reboxetine
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

Esreboxetine ((S,S)-Reboxetine) is a selective norepinephrine reuptake inhibitor with activity in increasing urethral resistance. Esreboxetine has been reported to be effective in patients with stress urinary incontinence in a Phase IIa clinical study, achieving this effect by increasing urethral closure. The mechanism of action of esreboxetine involves inhibition of norepinephrine transporters in the central and peripheral nervous systems. The peripheral selectivity of esreboxetine helps it significantly increase urethral resistance without penetrating the brain .
loading...
    loading...
Cat. No.: HY-14560S
CAS No.: 1285918-53-7
Purity:  ≥95.0%
Reboxetine-d5 mesylate is the deuterium labeled Reboxetine mesylatea (HY-14560). Reboxetine is an orally active, potent and selective noradrenaline uptake blocker. Reboxetine can be used for antidepressant research .
loading...
    loading...
Cat. No.: HY-14560A
CAS No.: 105017-39-8
Synonyms: (R,R)-FCE20124 mesylate; (R,R)-PNU155950E mesylate; (R,R)-(-)-Reboxetine mesylate
Research Areas:  

Neurological Disease

(R,R)-Reboxetine mesylate is an antidepressant agent with great bioavailability. (R,R)-Reboxetine is the enantiomer of Reboxetine, which is a selective noradrenaline reuptake inhibitor. Reboxetine consists of (R,R) and (S,S) enantiomer, has low affinity for alpha-adrenergic and muscarinic receptors and low toxicity in animals .
loading...
    loading...
Cat. No.: HY-14560CR
CAS No.: 98769-84-7
Synonyms: FCE20124 mesylate (Standard); PNU155950E mesylate (Standard)
Reboxetine (mesylate) (Standard) is the analytical standard of Reboxetine (mesylate). This product is intended for research and analytical applications. Reboxetine mesylate (FCE20124 mesylate) is a potent, selective, and specific noradrenaline reuptake inhibitor (NARI) for the research of depression. Reboxetine mesylate inhibits the uptake of norepinephrine, with a Ki of 8 nM .
loading...
    loading...
Cat. No.: HY-186094
CAS No.: 105018-14-2
Research Areas:  

Neurological Disease

(S,S)-Demethyl-reboxetine is a key phenolic precursor for the preparation of the PET tracer (S,S)-[ 11C]-MeNER. (S,S)-Demethyl-reboxetine is also the demethylated derivative of Reboxetine (HY-14560). Efficient synthesis of the norepinephrine transporter (NET)-targeted tracer is achieved through 11C methylation of (S,S)-Demethyl-reboxetine. (S,S)-Demethyl-reboxetine serves as a core raw material for the synthesis of radiopharmaceuticals related to NET imaging .
loading...
    loading...
Cat. No.: HY-186093
CAS No.: 252570-31-3
Target:  

Drug Intermediate

Research Areas:  

Others

(S,S)-Reboxetine-OH is a phenol compound. (S,S)-Reboxetine-OH can be used to synthesize norepinephrine transporter ligand .
loading...
    loading...
Cat. No.: HY-183453
CAS No.: 351330-75-1
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease

O-Desethylreboxetine is the major metabolite of Reboxetine (HY-14560), which is catalyzed by the CYP3A4 enzyme. O-Desethylreboxetine can be used in depression-related research .
loading...
    loading...