Reboxetine mesylate (Standard)
Reboxetine (mesylate) (Standard) is the analytical standard of Reboxetine (mesylate). This product is intended for research and analytical applications. Reboxetine mesylate (FCE20124 mesylate) is a potent, selective, and specific noradrenaline reuptake inhibitor (NARI) for the research of depression. Reboxetine mesylate inhibits the uptake of norepinephrine, with a Ki of 8 nM.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 98769-84-7
- Formula: C20H27NO6S
- Molecular Weight:409.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 98769-84-7
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Molecular Weight 409.50
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Formula C20H27NO6S
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SMILES
CS(=O)(O)=O.CCOC1=C(C=CC=C1)O[C@]([C@@]2([H])CNCCO2)([H])C3=CC=CC=C3
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Synonyms
FCE20124 mesylate (Standard); PNU155950E mesylate (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wong, E.H., et al., Reboxetine: a pharmacologically potent, selective, and specific norepinephrine reuptake inhibitor. Biol Psychiatry, 2000. 47(9): p. 818-29. [Content Brief]
[2]. Versiani, M., et al., Reboxetine, a unique selective NRI, prevents relapse and recurrence in long-term treatment of major depressive disorder. J Clin Psychiatry, 1999. 60(6): p. 400-6. [Content Brief]
[3]. M Leskiewicz, et al. Antidepressants attenuate the dexamethasone-induced decrease in viability and proliferation of human neuroblastoma SH-SY5Y cells: a involvement of extracellular regulated kinase (ERK1/2). Neurochem Int. 2013 Nov;63(5):354-62. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)