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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
66 Results for "
S 7
" in MedChemExpress (MCE) Product Catalog:
Products (66)
66 Results for "S 7" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P10284
CAS No.: 853248-13-2
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34
34 Publications Verification
Synonyms: Necrostatin 1S; Nec-1S; 7-Cl-O-Nec1
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Necrostatin 2 racemate (Nec-1S), the Necrostatin-1 (HY-15760) stable, is a potent and specific RIPK1 inhibitor lacking the IDO-targeting effect .
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1
1 Cited Publications
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SecinH3 is an antagonist of cytohesins with IC50s of 5.4 μM, 2.4 μM, 5.4 μM, 5.6 μM, 5.6 μM and 65 μM for hCyh1, hCyh2, mCyh3, hCyh3, drosophila steppke and yGea2-S7, respectively.
Cat. No.: HY-159520
CAS No.: 2731294-23-6
Synonyms: Ofirnoflast; HT-6184
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Ofirnoflastum (Ofirnoflast) is an orally active first-in-class allosteric NEK7 inhibitor with an IC50 of 46 nM. Ofirnoflastum binds an allosteric site adjacent to NEK7’s ATP-binding pocket, induces conformational shifts, disrupts NEK7-NLRP3 binding, blocks NLRP3 inflammasome assembly, spares NEK7’s physiological functions, and suppresses caspase-1, caspase-8, NF-κB, and TNF activity. Ofirnoflastum reduces pro-inflammatory cytokine production, suppresses ASC specks, IL-1β release, pyroptotic cell death, and leukemic burden, induces apoptosis and erythroid differentiation, restores hematopoiesis, and improves outcomes in colitis models. Ofirnoflastum can be used for the research of myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia .
Cat. No.: HY-W106164A
CAS No.: 2820537-15-1
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((2S,7aS)-2-Fluorohexahydro-1H-pyrrolizin-7a-yl)methanol is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-133885
CAS No.: 856925-75-2
Cat. No.: HY-W091788
CAS No.: 908130-61-0
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(2S,3R,5S)-7-Deaza-2'-deoxy-7-iodoadenosine is the isomer of 7-Deaza-2'-deoxy-7-iodoadenosine (HY-W048490), and can be used as an experimental control. 7-Deaza-2'-deoxy-7-iodoadenosine is a modified oligonucleotide containing 7-Deazaadenine .
Cat. No.: HY-N2207
CAS No.: 178740-32-4
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Other Diseases Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill.
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Cat. No.: HY-174129
CAS No.: 2649008-95-5
TM471-1 is an orally active and covalent Bruton's tyrosine kinase (BTK) inhibitor with IC50 values of 1.3 nM (BTK WT), >40,000 nM (BTK C481S), 7.9 nM (TEC) and 12.4 nM (TXK). TM471-1 inhibits cell growth in vivo and in vitro, arrests cell cycle at G0/G1 phase and induces cell apoptosis .
Cat. No.: HY-N0291R
CAS No.: 29745-04-8
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(±)-Norcantharidin (Standard) is the analytical standard of (±)-Norcantharidin. This product is intended for research and analytical applications. (±)-Norcantharidin ((±)-NCTD) is a compound possessing anti-angiogenetic activity with potential use in anti-cancertherapy. (±)-Norcantharidin could prevent tumorigenesis by inhibiting cell proliferation, inducing apoptosis and the cell cycle arrest, and anti-angiogenic effects .
Cat. No.: HY-W742809
CAS No.: 63740-81-8
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(S)-7-Hydroxywarfarin is the S stereoisomer of 7-Hydroxywarfarin (HY-139167). (S)-7-Hydroxywarfarin is the inactive, major metabolite of racemic Warfarin (HY-B0687) .
Cat. No.: HY-163892
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POLRMT-IN-1 (compound S7) is a POLRMT inhibitor. POLRMT-IN-1 can be used in cancer-related research .
Cat. No.: HY-N2747
CAS No.: 100079-34-3
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Cat. No.: HY-B0395DS
Synonyms: (1R,2S,7R)-DU6859a-d4 hydrochloride
Cat. No.: HY-N12068
CAS No.: 214627-06-2
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Cat. No.: HY-N2738
CAS No.: 376361-96-5
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Cat. No.: HY-W095672AS4
CAS No.: 2883770-63-4
Synonyms: (2S,7aR)-2-Fluorotetrahydro-1H-pyrrolizine-7a(5H)-methanol-d2
Cat. No.: HY-W106164AS
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
