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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
S-oxide
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "S-oxide" in MCE Product Catalog:
5
5 Cited Publications
Synonyms: Acetothioamide; TAA; Thiacetamide
Target:
Research Areas:
Thioacetamide (TAA) is an indirect hepatotoxin and causes parenchymal cell necrosis. Thioacetamide requires metabolic activation by microsomal CYP2E1 to thioacetamide-S-oxide initially and then to thioacetamide-S-dioxide, which is a highly reactive metabolite, and its reactive metabolites covalently bind to proteins and lipids thereby causing oxidative stress and centrilobular necrosis. Thioacetamide can induce chronic liver fibrosis, encephalopathy and other events model .
1
1 Cited Publications
Cat. No.: HY-G0014A
CAS No.: 329218-11-3
Synonyms: Quetiapine S-oxide dihydrochloride
Target:
Research Areas:
Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic . Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist .
Cat. No.: HY-133152
CAS No.: 1191900-51-2
Synonyms: DM-3411
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Brexpiprazole S-oxide (DM-3411) is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). Brexpiprazole is an atypical antipsychotic agent and a partial agonist of human 5-HT1A and dopamine receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM .
Cat. No.: HY-W007359
CAS No.: 123-90-0
Cat. No.: HY-100096
CAS No.: 152128-77-3
Synonyms: Emtricitabine sulfoxide; Emtricitabine Degradant-III
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Research Areas:
Emtricitabine S-oxide (Emtricitabine sulfoxide) is a major degradation product of Emtricitabine. Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.
Cat. No.: HY-W011245
CAS No.: 73851-70-4
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Ranitidine S-oxide is the metabolite of Ranitidine (HY-B0693). Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion .
Cat. No.: HY-G0014
CAS No.: 329216-63-9
Synonyms: Quetiapine S-oxide
Target:
Research Areas:
Quetiapine sulfoxide (Quetiapine S-oxide) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic . Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist .
Cat. No.: HY-100096A
CAS No.: 2733287-29-9
Synonyms: (Rac)-Emtricitabine sulfoxide; (Rac)-Emtricitabine Degradant-III
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(Rac)-Emtricitabine S-oxide ((Rac)-Emtricitabine sulfoxide; (Rac)-Emtricitabine Degradant-III) is Emtricitabine S-oxide (HY-100096) racemic modification. Emtricitabine S-oxide is a major degradation product of Emtricitabine. Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.
Synonyms: DM-3411 d8
Cat. No.: HY-W011245R
CAS No.: 73851-70-4
Target:
Research Areas:
Ranitidine S-oxide (Standard) is the analytical standard of Ranitidine S-oxide. This product is intended for research and analytical applications. Ranitidine S-oxide is the metabolite of Ranitidine (HY-B0693). Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion .
Cat. No.: HY-G0014B
CAS No.: 2448341-72-6
Synonyms: Quetiapine S-oxide hydrochloride
Target:
Research Areas:
Quetiapine sulfoxide hydrochloride (Quetiapine S-oxide hydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic . Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist .
Cat. No.: HY-G0014AR
CAS No.: 329218-11-3
Synonyms: Quetiapine S-oxide dihydrochloride (Standard)
Target:
Research Areas:
Quetiapine sulfoxide (dihydrochloride) (Standard) is the analytical standard of Quetiapine sulfoxide (dihydrochloride). This product is intended for research and analytical applications. Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1]. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist[2].
Cat. No.: HY-E71336
Target:
Research Areas:
γ-Glutamyl hercynylcysteine S-oxide hydrolase (EC 3.5.1.118) is part of the biosynthesis pathway of ergothioneine in mycobacteria.
Cat. No.: HY-W740402
CAS No.: 1185170-04-0
Synonyms: 7-Hydroxy quetiapine S-oxide
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Quetiapine impurity 12 (7-Hydroxy quetiapine S-oxide) is an impurity of Quetiapine.
Cat. No.: HY-E71337
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γ-Glutamyl hercynylcysteine S-oxide synthase (EC 1.14.99.50) requires Fe2+ for activity. The enzyme, found in bacteria, is specific for both hercynine and γ-L-Glutamyl-L-cysteine. It is part of the biosynthesis pathway of ergothioneine.
Cat. No.: HY-127059
CAS No.: 22431-46-5
Synonyms: U-25026A
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Research Areas:
Clindamycin sulfoxide is an active metabolite of the antibiotic Clindamycin (HY-B1455). It is formed via S-oxidation of clindamycin primarily by the cytochrome P450 (CYP) isoform CYP3A4. Clindamycin sulfoxide inhibits the growth of P. prevotti, B. fragilis, and C. sordelli in vitro with MIC values of 2, 2, and 1 mg/L, respectively.
Cat. No.: HY-G0014S
CAS No.: 1330238-38-4
Cat. No.: HY-120714
CAS No.: 13993-65-2
Synonyms: 16091 RP
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Research Areas:
Metiazinic acid (16091 RP) is an orally active and brain-penetrant phenothiazine derivative and a non-steroidal anti-inflammatory drug (NSAID). Metiazinic acid can be used for the research of inflammatory conditions .
Synonyms: Acetothioamide (Standard); TAA (Standard); Thiacetamide (Standard)
Target:
Research Areas:
Thioacetamide (Standard) is the analytical standard of Thioacetamide (HY-Y0698). This product is intended for research and analytical applications. Thioacetamide (TAA) is an indirect hepatotoxin and causes parenchymal cell necrosis. Thioacetamide requires metabolic activation by microsomal CYP2E1 to thioacetamide-S-oxide initially and then to thioacetamide-S-dioxide, which is a highly reactive metabolite, and its reactive metabolites covalently bind to proteins and lipids thereby causing oxidative stress and centrilobular necrosis. Thioacetamide can induce chronic liver fibrosis, encephalopathy and other events model .
Cat. No.: HY-127059S
Synonyms: U-25026A-13C,d3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
