1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. Quetiapine sulfoxide hydrochloride

Quetiapine sulfoxide hydrochloride (Synonyms: Quetiapine S-oxide hydrochloride)

Cat. No.: HY-G0014B Purity: 96.92%
Handling Instructions

Quetiapine sulfoxide hydrochloride (Quetiapine S-oxide hydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist.

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Quetiapine sulfoxide hydrochloride Chemical Structure

Quetiapine sulfoxide hydrochloride Chemical Structure

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Description

Quetiapine sulfoxide hydrochloride (Quetiapine S-oxide hydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1]. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist[2].

In Vivo

The Cmax value (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUClast value is estimated for Quetiapine sulfoxide (1,286±458 ng•h/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing[1].

Molecular Weight

435.97

Formula

C₂₁H₂₆ClN₃O₃S

SMILES

OCCOCCN(CC1)CCN1C2=NC(C=CC=C3)=C3S(C4=C2C=CC=C4)=O.Cl[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

Quetiapine sulfoxideQuetiapine S-oxideDrug MetaboliteInhibitorinhibitorinhibit

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Quetiapine sulfoxide hydrochloride
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HY-G0014B
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