Clindamycin sulfoxide-¹³C,d₃  (Synonyms: U-25026A-¹³C,d₃)

Clindamycin sulfoxide-¹³C,d₃ (U-25026A-¹³C,d₃) is the deuterium and ¹³C-labeled Clindamycin sulfoxide (HY-127059). Clindamycin sulfoxide is an active metabolite of the antibiotic Clindamycin (HY-B1455). It is formed via S-oxidation of clindamycin primarily by the cytochrome P450 (CYP) isoform CYP3A4. Clindamycin sulfoxide inhibits the growth of P. prevotti, B. fragilis, and C. sordelli in vitro with MIC values of 2, 2, and 1 mg/L, respectively.

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

444.99

C₁₇¹³CH₃₀D₃ClN₂O₆S

22431-46-5

O=C([C@H]1N(C[C@@H](C1)CCC)[13C]([2H])([2H])[2H])N[C@@]([H])([C@]2(O[C@@]([H])([C@@H]([C@H]([C@H]2O)O)O)S(C)=O)[H])[C@@H](Cl)C

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.