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Cat. No.: HY-127059S

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Clindamycin sulfoxide-¹³C,d₃

(Synonyms: U-25026A-¹³C,d₃)

Clindamycin sulfoxide-¹³C,d₃ (U-25026A-¹³C,d₃) is the deuterium and ¹³C-labeled Clindamycin sulfoxide (HY-127059). Clindamycin sulfoxide is an active metabolite of the antibiotic Clindamycin (HY-B1455). It is formed via S-oxidation of clindamycin primarily by the cytochrome P450 (CYP) isoform CYP3A4. Clindamycin sulfoxide inhibits the growth of P. prevotti, B. fragilis, and C. sordelli in vitro with MIC values of 2, 2, and 1 mg/L, respectively.

For research use only. We do not sell to patients.

Formula: C₁₇¹³CH₃₀D₃ClN₂O₆S
Molecular Weight:444.99

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Clindamycin sulfoxide-¹³C,d₃ Chemical Structure

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Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Antibiotic Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 22431-46-5
Molecular Weight 444.99
Formula C₁₇¹³CH₃₀D₃ClN₂O₆S
SMILES

O=C([C@H]1N(C[C@@H](C1)CCC)[13C]([2H])([2H])[2H])N[C@@]([H])([C@]2(O[C@@]([H])([C@@H]([C@H]([C@H]2O)O)O)S(C)=O)[H])[C@@H](Cl)C
Synonyms

U-25026A-¹³C,d₃
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.