73851-70-4
73851-70-4
Chemical Structure
Ranitidine S-oxide
- CAS No.: 73851-70-4
- Formula:C13H22N4O4S
- Molecular Weight:330.41
IUPAC Name: (E)-N-(2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)sulfinyl)ethyl)-N'-methyl-2-nitroethene-1,1-diamine
InChIKey: SKHXRNHSZTXSLP-UKTHLTGXSA-N
SMILES: O=[N+](/C=C(NCCS(CC1=CC=C(CN(C)C)O1)=O)\NC)[O-]
Biological Activity: Ranitidine S-oxide is the metabolite of Ranitidine (HY-B0693). Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion[1][2].
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Ranitidine S-oxide | Ranitidine S-oxide is the metabolite of Ranitidine (HY-B0693). Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion. | |||||||||||||||||||||
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Ranitidine S-oxide (Standard) | ≥98% | Ranitidine S-oxide (Standard) is the analytical standard of Ranitidine S-oxide. This product is intended for research and analytical applications. Ranitidine S-oxide is the metabolite of Ranitidine (HY-B0693). Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion. | ||||||||||||||||||||
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References
- [1]. Cross DM, et al. Kinetics of ranitidine metabolism in dog and rat isolated hepatocytes. Xenobiotica. 1995 Apr;25(4):367-75. [Content Brief]
- [2]. Leucuta A, et al. A pharmacokinetic interaction study between omeprazole and the H2-receptor antagonist ranitidine. Drug Metabol Drug Interact. 2004;20(4):273-81. [Content Brief]
