11 Results for "

SNARE

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "SNARE" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-129111
CAS No.: 864941-31-1
Purity:  99.49%
Target:  

Autophagy

Research Areas:  

Infection Neurological Disease

EACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion .
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Cat. No.: HY-100355
CAS No.: 2304-81-6
Purity:  99.95%
Synonyms: C18-Ceramide
C18-Ceramide (d18:1/18:0) is a bioactive molecule with multiple functions in cells, not a traditional agonist or inhibitor targeting a single site. It can act on multiple cellular targets, such as proteins related to endoplasmic reticulum stress (e.g., ATF-4, XBP-1, CHOP), proteins in the PI3K/AKT signaling pathway, and SNARE complex proteins. It exerts activities like inducing cell death, promoting autophagy, and regulating exocytosis through mechanisms such as activating endoplasmic reticulum stress, inhibiting the PI3K/AKT signaling pathway, and affecting lipid raft - related functions. It can be used in research on the mechanism of neuronal injury in the field of neuroscience and in the treatment research of cancers such as glioma in the field of oncology .
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Cat. No.: HY-W042156
CAS No.: 456-12-2
Aegeline, a main alkaloid, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast. Aegeline restores growth of yeast cells suppressed by either αsyn or Bax. Antioxidant activity .
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Cat. No.: HY-15784
CAS No.: 432020-20-7
Purity:  99.60%
Target:  

Fungal

Research Areas:  

Infection Inflammation/Immunology

NPPM 6748-481 is a potent and selective yeast Sec14 inhibitor with a yeast Sec14 IC50 of 211 nM. NPPM 6748-481 disrupts membrane trafficking, impairing trans-Golgi network-endosomal transport and endocytic transport. NPPM 6748-481 impairs Snc1 v-SNARE recycling, secretory invertase trafficking, and vacuolar carboxypeptidase Y processing. NPPM 6748-481 can be used for research on yeast infection .
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Cat. No.: HY-W042156R
CAS No.: 456-12-2
Aegeline (Standard) is the analytical standard of Aegeline. This product is intended for research and analytical applications. Aegeline, a main alkaloid, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast. Aegeline restores growth of yeast cells suppressed by either αsyn or Bax. Antioxidant activity .
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Cat. No.: HY-RS19357
Research Areas:  

Others

Napg Mouse Pre-designed siRNA Set A contains three designed siRNAs for Napg gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-149590
CAS No.: 200348-48-7
Target:  

Phosphatase

Research Areas:  

Others

IPA is a specific Sec18/NSF inhibitor. IPA binds to phosphatidic acid competitively, induces conformational rigidification of Sec18/NSF, disrupts its essential flexibility, and blocks SNARE priming and vacuolar membrane fusion. IPA can be used to investigate the activity of Sec18 and SNARE priming kinetics .
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Cat. No.: HY-182539
CAS No.: 1202877-06-2
Target:  

CGRP Receptor

Research Areas:  

Others Neurological Disease

DD04107 is a neuronal exocytosis inhibitor with a rat Syt1-C2B domain binding Ka of 2.4 μM. DD04107 interferes with synaptobrevin-syntaxin-SNAP-25 complex formation and Syt1-SNARE complex interaction to block α-calcitonin gene-related peptide (α-CGRP) exocytotic release from primary sensory neurons. DD04107 blocks inflammatory ion channel recruitment to nociceptor plasma membranes. DD04107 can be used for the research of chronic inflammatory pain, neuropathic pain, osteosarcoma pain, chemotherapy-induced peripheral neuropathy, diabetic neuropathy, inflammatory pain .
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Cat. No.: HY-RS18143
Research Areas:  

Others

Napa Mouse Pre-designed siRNA Set A contains three designed siRNAs for Napa gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P87146
Synonyms: HGNC:17793 antibody; V SNARE antibody; v-SNARE antibody; Vesicle associated soluble NSF attachment protein receptor antibody; Vesicle transport through interaction with t SNAREs 1B antibody; Vesicle transport through interaction with t SNAREs homolog 1B (yeast) antibody; Vesicle transport through interaction with t-SNAREs homolog 1B antibody; Vesicle transport v-SNARE protein Vti1-like 1 antibody; VTI1 antibody; VTI1 like antibody; HGNC:17793 antibody; V SNARE antibody; v-SNARE antibody; Vesicle associated soluble NSF attachment protein receptor antibody; Vesicle transport through interaction with t SNAREs 1B antibody; Vesicle transport through interaction with t SNAREs homolog 1B (yeast) antibody; Vesicle transport through interaction with t-SNAREs homolog 1B antibody; Vesicle transport v-SNARE protein Vti1-like 1 antibody; VTI1 antibody; VTI1 like antibody; Vti1 rp1 antibody; VTI1-LIKE antibody; Vti1-rp1 antibody; VTI1B antibody; VTI1B_HUMAN antibody; VTI1L antibody; VTI1L1 antibody; VTI2 antibody;

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P811218
Synonyms: SEC22L1, SEC22B, Vesicle-trafficking protein SEC22b, ER-Golgi SNARE of 24 kDa, SEC22 vesicle-trafficking protein homolog B, SEC22 vesicle-trafficking protein-like 1, ERS-24, ERS24

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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