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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
Sacubitril
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "Sacubitril" in MCE Product Catalog:
3
Target:
Research Areas:
Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19 .
10
Target:
Research Areas:
Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure . Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis .
7
Target:
Research Areas:
Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor.
3
3 Cited Publications
Synonyms: AHU-377 sodium
Target:
Research Areas:
Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19 .
3
3 Cited Publications
Synonyms: AHU-377 hemicalcium salt
Target:
Research Areas:
Sacubitril hemicalcium salt (AHU-377 hemicalcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696.
Synonyms: AHU-377-d4
Cat. No.: HY-78841
CAS No.: 149709-63-7
Target:
Research Areas:
(2S,4S)-Sacubitril is the impurity of Sacubitril. Sacubitril is a potent NEP inhibitor that can be used for the research of heart failure .
Cat. No.: HY-78847
CAS No.: 761373-05-1
Target:
Research Areas:
2R,4S-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
Cat. No.: HY-15407BR
CAS No.: 149690-05-1
Synonyms: AHU-377 sodium (Standard)
Target:
Research Areas:
Sacubitril (sodium) (Standard) is the analytical standard of Sacubitril (sodium). This product is intended for research and analytical applications. Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19 .
Cat. No.: HY-78846
CAS No.: 2259708-00-2
Target:
Research Areas:
2R,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
Cat. No.: HY-Z0081
CAS No.: 2307668-79-5
Target:
Research Areas:
2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
Cat. No.: HY-17620R
CAS No.: 149709-44-4
Synonyms: Desethyl Sacubitril (Standard); LBQ-657 (Standard)
Target:
Research Areas:
Sacubitrilat (Standard) is the analytical standard of Sacubitrilat. This product is intended for research and analytical applications. Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor.
Cat. No.: HY-15407R
CAS No.: 149709-62-6
Synonyms: AHU-377 (Standard)
Target:
Research Areas:
Sacubitril (Standard) is the analytical standard of Sacubitril. This product is intended for research and analytical applications. Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19 .
Cat. No.: HY-78847R
CAS No.: 761373-05-1
Target:
Research Areas:
2R,4S-Sacubitril (Standard) is the analytical standard of 2R,4S-Sacubitril. This product is intended for research and analytical applications. 2R,4S-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
Cat. No.: HY-Z0075
Target:
Research Areas:
(Z)2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
Cat. No.: HY-Z0075R
CAS No.: 2751722-77-5
Target:
Research Areas:
(Z)2S,4R-Sacubitril (Standard) is the analytical standard of (Z)2S,4R-Sacubitril. This product is intended for research and analytical applications. (Z)2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
Cat. No.: HY-15407AS1
Purity: 98.78%
Synonyms: AHU-377-d4 hemicalcium salt
Cat. No.: HY-15407AS
Synonyms: AHU-377-13C4 hemicalcium salt
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
