Sacubitrilat (Standard)
Sacubitrilat (Standard) is the analytical standard of Sacubitrilat. This product is intended for research and analytical applications. Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 149709-44-4
- Formula: C22H25NO5
- Molecular Weight:383.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 149709-44-4
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Molecular Weight 383.44
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Formula C22H25NO5
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SMILES
[H]N(C(CCC(O)=O)=O)[C@H](CC(C=C1)=CC=C1C2=CC=CC=C2)C[C@H](C(O)=O)C
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Synonyms
Desethyl Sacubitril (Standard); LBQ-657 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Schiering N, et al. Structure of neprilysin in complex with the active metabolite of sacubitril. Sci Rep. 2016 Jun 15;6:27909. [Content Brief]
[2]. Langenickel TH, et al. Single therapeutic and supratherapeutic doses of sacubitril/valsartan (LCZ696) do not affect cardiac repolarization. Eur J Clin Pharmacol. 2016 Aug;72(8):917-24. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)