(Z)2S,4R-Sacubitril
Based on 1 Customer Validation
(Z)2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
For research use only. We do not sell to patients.
- Purity: 96.89%
- Formula: C24H27NO5
- Molecular Weight:409.47
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Metabolism/Protease Compound Library
HY-L012
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Covalent Screening Library
HY-L036
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Anti-Cardiovascular Disease Compound Library
HY-L046
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Drug Metabolite Library
HY-L098
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Cysteine Targeted Covalent Library
HY-L153
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Bioactive Compound Library Max
HY-L181
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HY-L001V
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HY-L036P
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 409.47
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Formula C24H27NO5
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Color White to off-white
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SMILES
[H]N(C(/C=C\C(O)=O)=O)[C@H](CC(C=C1)=CC=C1C2=CC=CC=C2)C[C@@H](C)C(OCC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 100 mg/mL (244.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4422 mL | 12.2109 mL | 24.4218 mL | 61.0545 mL |
| 5 mM | 0.4884 mL | 2.4422 mL | 4.8844 mL | 12.2109 mL | |
| 10 mM | 0.2442 mL | 1.2211 mL | 2.4422 mL | 6.1055 mL | |
| 15 mM | 0.1628 mL | 0.8141 mL | 1.6281 mL | 4.0703 mL | |
| 20 mM | 0.1221 mL | 0.6105 mL | 1.2211 mL | 3.0527 mL | |
| 25 mM | 0.0977 mL | 0.4884 mL | 0.9769 mL | 2.4422 mL | |
| 30 mM | 0.0814 mL | 0.4070 mL | 0.8141 mL | 2.0352 mL | |
| 40 mM | 0.0611 mL | 0.3053 mL | 0.6105 mL | 1.5264 mL | |
| 50 mM | 0.0488 mL | 0.2442 mL | 0.4884 mL | 1.2211 mL | |
| 60 mM | 0.0407 mL | 0.2035 mL | 0.4070 mL | 1.0176 mL | |
| 80 mM | 0.0305 mL | 0.1526 mL | 0.3053 mL | 0.7632 mL | |
| 100 mM | 0.0244 mL | 0.1221 mL | 0.2442 mL | 0.6105 mL |
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