Sacubitril (Standard)
Based on 1 Customer Validation
Sacubitril (Standard) is the analytical standard of Sacubitril. This product is intended for research and analytical applications. Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 149709-62-6
- Fòrmula: C24H29NO5
- Peso molecular:411.49
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Pureza y Documentación
-
Help & FAQs
-
HY-15407
SacubitrilNEP Inhibitor -
HY-17620
SacubitrilatNEP Inhibitor -
HY-15407A
Sacubitril hemicalcium saltNEP Inhibitor -
HY-17399
RacecadotrilNEP -
HY-B0202
IrbesartanAT1 Receptor Blocker -
HY-W013375
ThiorphanNEP Inhibitor -
HY-18204A
Sacubitril/ValsartanARN Inhibitor -
HY-B0130
PerindoprilAngiotensin-converting enzyme Inhibitor -
HY-17512
LosartanAngiotensin II Receptor Antagonist -
HY-17620R
Sacubitrilat (Standard)NEP Inhibitor -
HY-B0195
TranilastAnti-allergic Agent -
HY-19649
Candoxatril
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
No. CAS 149709-62-6
-
Appearance Solid
-
Peso molecular 411.49
-
Fòrmula C24H29NO5
-
Color White to off-white
-
SMILES
O=C(CCC(O)=O)N[C@H](CC1=CC=C(C2=CC=CC=C2)C=C1)C[C@@H](C)C(OCC)=O
-
Synonyms
AHU-377 (Standard)
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
[1]. Ksander GM, et al. Dicarboxylic acid dipeptide neutral endopeptidase inhibitors. J Med Chem. 1995 May 12;38(10):1689-700. [Content Brief]
[2]. Voors AA, et al. The potential role of valsartan + AHU377 ( LCZ696 ) in the treatment of heart failure. Expert Opin Investig Drugs. 2013 Aug;22(8):1041-7. [Content Brief]
[3]. von Lueder TG, et al. Angiotensin receptor neprilysin inhibitor LCZ696 attenuates cardiac remodeling and dysfunction after myocardial infarction by reducing cardiac fibrosis and hypertrophy. Circ Heart Fail. 2015 Jan;8(1):71-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sacubitril (Standard) Related Classifications
HY-15407R Related Classifications
Powered by Bioz