1884269-07-1
1884269-07-1
Chemical Structure
Sacubitril-d4
Synonym(s): AHU-377-d4
- CAS No.: 1884269-07-1
- Formula:C24H25D4NO5
- Molecular Weight:415.52
IUPAC Name: 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic-2,2,3,3-d4 acid
InChIKey: PYNXFZCZUAOOQC-JCZLLWNUSA-N
SMILES: C[C@H](C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(C([2H])(C([2H])(C(O)=O)[2H])[2H])=O)C(OCC)=O
Biological Activity: Sacubitril-d4 is the deuterium labeled Sacubitril. Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril (AHU-377) is a component of the heart failure medicine LCZ696.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sacubitril-d4 | 98.54% | Sacubitril-d4 is the deuterium labeled Sacubitril. Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril (AHU-377) is a component of the heart failure medicine LCZ696. | ||||||||||||||||||||
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Sacubitril (Standard) | 99.85% | Sacubitril (Standard) is the analytical standard of Sacubitril. This product is intended for research and analytical applications. Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19. | ||||||||||||||||||||
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Sacubitril-13C4 | Sacubitril-13C4 (AHU-377-13C4) is a 13C-labeled version of Sacubitril (HY-15407). Sacubitril is an orally active inhibitor of neprilysin NEP (IC50=5 nM). Sacubitril is used in research on heart failure, hypertension and COVID-19. | |||||||||||||||||||||
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Sacubitril | 99.92% | Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19. | ||||||||||||||||||||
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