Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
493 Results for "
TNFRSF
" in MedChemExpress (MCE) Product Catalog:
Products (493)
493 Results for "TNFRSF" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: Phen-DC3 Triflate
Target:
Phen-DC3 Trifluoromethanesulfonate is a bisquinolinium G-quadruplex (G4) ligand. Phen-DC3 Trifluoromethanesulfonate selectively binds to and stabilizes the hybrid quadruplex-duplex hybrid (QDH) derived from the PIM1 promoter. Phen-DC3 Trifluoromethanesulfonate also binds to the c-myc promoter Pu24T G4 via extensive π-stacking, and induces polymerase stalling at α-synuclein DNA and RNA G4 sequences. Phen-DC3 Trifluoromethanesulfonate downregulates LPS (HY-D1056)-induced TNFRSF21, RIPK3 and p-MLKL in VECs, and ameliorates CLP-induced pulmonary vascular leakage in septic rats. Phen-DC3 Trifluoromethanesulfonate can be used in studies related to neurodegenerative diseases and sepsis-associated vascular injury .
3
Target:
Research Areas:
2
2
1
1
1 Cited Publications
Cat. No.: HY-P700432
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor Necrosis Factor Receptor Superfamily Member 11B; Osteoclastogenesis Inhibitory Factor; Osteoprotegerin; TNFRSF11B; OCIF; OPG
1
1
Target:
1
1 Cited Publications
Target:
Research Areas:
ICCB-19 hydrochloride is a TRADD (TNFRSF1A associated via death domain) inhibitor. ICCB-19 hydrochloride binds with N-terminal domain of TRADD (TRADD-N), disrupting its binding to both TRADD-C and TRAF2. ICCB-19 hydrochloride is indirect inhibitor of RIPK1 kinase activity. ICCB-19 hydrochloride effectively induces autophagy and the degradation of long-lived proteins .
1
1
1 Cited Publications
Cat. No.: HY-P70023
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuTumor necrosis factor receptor superfamily member 8/CD30, His; Tumor necrosis factor receptor superfamily member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD30; TNFRSF8
1
Cat. No.: HY-RS14800
Target:
Research Areas:
Tnfrsf11a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfrsf11a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14801
Target:
Research Areas:
Tnfrsf11a Rat Pre-designed siRNA Set A contains three designed siRNAs for Tnfrsf11a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14803
Target:
Research Areas:
TNFRSF12A Human Pre-designed siRNA Set A contains three designed siRNAs for TNFRSF12A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-174513
Target:
Research Areas:
Human TNFRSF8 mRNA encodes the human TNF receptor superfamily member 8 (TNFRSF8) protein, a member of the TNF receptor superfamily. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
Cat. No.: HY-P990528
Target:
Research Areas:
Cat. No.: HY-RS14806
Target:
Research Areas:
TNFRSF14 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFRSF14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
