1803605-68-6
1803605-68-6
Chemical Structure
ICCB-19 hydrochloride
- CAS No.: 1803605-68-6
- Formula:C12H22ClN3OS
- Molecular Weight:291.84
IUPAC Name: N-cycloheptyl-2-((4,5-dihydro-1H-imidazol-2-yl)thio)acetamide hydrochloride
InChIKey: TZICOTBZKPHMMK-UHFFFAOYSA-N
SMILES: O=C(NC1CCCCCC1)CSC2=NCCN2.[H]Cl
Biological Activity: ICCB-19 hydrochloride is a TRADD (TNFRSF1A associated via death domain) inhibitor. ICCB-19 hydrochloride binds with N-terminal domain of TRADD (TRADD-N), disrupting its binding to both TRADD-C and TRAF2. ICCB-19 hydrochloride is indirect inhibitor of RIPK1 kinase activity. ICCB-19 hydrochloride effectively induces autophagy and the degradation of long-lived proteins[1].
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ICCB-19 hydrochloride | 99.25% | ICCB-19 hydrochloride is a TRADD (TNFRSF1A associated via death domain) inhibitor. ICCB-19 hydrochloride binds with N-terminal domain of TRADD (TRADD-N), disrupting its binding to both TRADD-C and TRAF2. ICCB-19 hydrochloride is indirect inhibitor of RIPK1 kinase activity. ICCB-19 hydrochloride effectively induces autophagy and the degradation of long-lived proteins. | ||||||||||||||||||||
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