157 Results for "

Transfection

" in MedChemExpress (MCE) Product Catalog:
Products (157)

157 Results for "Transfection" in MCE Product Catalog:

65
65 Publications Verification
Cat. No.: HY-K2014

MCE PEI Transfection Reagent is designed based on 25 kDa PEI. It has high-efficiency, low-toxicity, strong-stability, and is suitable for many cell types, such as HEK-293、HEK-293T、CHO-K1、COS-1、COS-7、NIH/3T3、Sf9、HepG2 and HeLa et, even some hard-to-transfect cells. It can also be applied to large-scale recombinant protein expression and virus production. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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50
50 Cited Publications
Cat. No.: HY-134541
CAS No.: 2089251-47-6
Pureté:  99.97%
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
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41
41 Cited Publications
Cat. No.: HY-K1014

MCE PolyFast Transfection Reagent consists of cationic polymers and can introduce nucleic acids (DNA or RNA) into eukaryotic cells efficiently, including some hard-to-transfect cells.

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26
26 Cited Publications
Cat. No.: HY-112764
CAS No.: 160743-62-4
Pureté:  98.40%
mPEG2000-DMG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. mPEG2000-DMG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
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19
19 Cited Publications
Cat. No.: HY-112754A
CAS No.: 132172-61-3
Pureté:  99.91%
Synonyms: 1,2-Dioleoyl-3-trimethylammonium-propane chloride
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .
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19
19 Cited Publications
Cat. No.: HY-W127378
CAS No.: 144189-73-1
Synonyms: 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate
DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design .
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14
14 Cited Publications
Cat. No.: HY-K2017

MCE siRNA/miRNA Transfection Reagent is a novel cationic polymer transfection reagent for siRNA and miRNA transfection. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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12
12 Cited Publications
Cat. No.: HY-112005
CAS No.: 4004-05-1
Pureté:  98.80%
Synonyms: Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
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9
9 Cited Publications
Cat. No.: HY-W250110
CAS No.: 9002-98-6
Domaines de recherche:  

Infection Others

Polyethylenimine (branched) (30% in water) is a organic macromolecule with high cationic-charge-density potential. Polyethylenimine (branched) (30% in water) can ensnare DNA as well as attach to cell membrane. Polyethylenimine (branched) (30% in water) also retains a substantial buffering capacity at virtually any pH. Polyethylenimine (branched) (30% in water) is widely used as transfection reagent .
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5
5 Cited Publications
Cat. No.: HY-124493
CAS No.: 569-58-4
Synonyms: ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium
Aluminon (ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium) is a complexometric titration indicator and can also be used as a nuclease inhibitor affecting transfection. Aluminon is a kind of biological materials or organic compounds that are widely used in life science research .
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1
1 Cited Publications
Cat. No.: HY-W250110E
CAS No.: 9002-98-6
Synonyms: PEI (branched) (MW 25000)
Polyethylenimine (branched) is a commonly used non-viral DNA transfection reagent. Polyethylenimine (branched) (MW 25000) binds to plasmid DNA .
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1
1 Cited Publications
Cat. No.: HY-139200
CAS No.: 104872-42-6
Pureté:  ≥98.0%
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .
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1
1 Cited Publications
Cat. No.: HY-112760
CAS No.: 247925-28-6
Pureté:  ≥98.0%
Synonyms: DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
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1
1 Cited Publications
Cat. No.: HY-148859
CAS No.: 2938207-23-7
Pureté:  ≥98.0%
AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts .
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1
1 Cited Publications
Cat. No.: HY-K2015

MCE Lentivirus Transfection Reagent is a new type of transfection reagent based on cationic polymer, which is suitable for lentivirus packaging and transfection. It significantly improves the efficiency of packaging and transfection, resulting in the production of more recombinant lentivirus.

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1
1 Cited Publications
Cat. No.: HY-K2016

MCE Protein Transfection Reagent is a cationic lipid mixture for complexation with proteins, peptides, antibodies and other biologically active molecules to allow their direct intracellular delivery.

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1
1 Cited Publications
Cat. No.: HY-K2023

MCE In vivo OptiLNP RNA Transfection Reagent (Local Effect) is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient transfection of mRNA and short-chain RNA in experimental animals. The RNA functions locally.

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1
1 Cited Publications
Cat. No.: HY-P0328
CAS No.: 103425-05-4
Target:  

VSV

Domaines de recherche:  

Infection

VSV-G tag Peptide is a 11 amino acid peptide derived from the Vesicular Stomatitis viral glycoprotein. VSV-G tag Peptide can integrate into the cell membranes of animal cells, induce cell fusion, and significantly enhance the efficiency of DNA transfection into animal cells. VSV-G tag Peptide can be used for research on drug delivery .
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1
1 Cited Publications
Cat. No.: HY-142118
CAS No.: 925681-61-4
Synonyms: AP 12009
Target:  

TGF-beta/Smad

Domaines de recherche:  

Cancer

Trabedersen (AP 12009) is an orally active synthetic antisense phosphorothioate oligodeoxynucleotide that selectively targets human TGFβ2 mRNA. Trabedersen blocks TGFβ2 protein production, enters the nucleus without a transfection vector, and exerts dose-dependent antitumor effects. By reversing TGFβ2-induced immunosuppression and enhancing immune cytotoxicity, Trabedersen exhibits significant antiproliferative, antimigratory, and antimetastatic activities, with favorable safety profiles. Trabedersen is widely used in research related to various solid tumors, including anaplastic astrocytoma, glioblastoma, colorectal tumor, and melanoma .
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1
1 Cited Publications
Cat. No.: HY-142118A
Pureté:  92.09%
Synonyms: AP 12009 sodium
Target:  

TGF-beta/Smad

Domaines de recherche:  

Cancer

Trabedersen (AP 12009) sodium is an orally active synthetic antisense phosphorothioate oligodeoxynucleotide that selectively targets human TGFβ2 mRNA. Trabedersen sodium blocks TGFβ2 protein production, enters the nucleus without a transfection vector, and exerts dose-dependent antitumor effects. By reversing TGFβ2-induced immunosuppression and enhancing immune cytotoxicity, Trabedersen sodium exhibits significant antiproliferative, antimigratory, and antimetastatic activities, with favorable safety profiles. Trabedersen sodium is widely used in research related to various solid tumors, including anaplastic astrocytoma, glioblastoma, colorectal tumor, and melanoma .
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