27 Results for "

Tsp-1

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "Tsp-1" in MCE Product Catalog:

18
18 Publications Verification
Cat. No.: HY-P0299
CAS No.: 283609-79-0
Target:  

TGF-β Receptor

Research Areas:  

Cancer

LSKL, Inhibitor of Thrombospondin (TSP-1) is a latency-associated protein (LAP)-TGFβ derived tetrapeptide and a competitive TGF-β1 antagonist. LSKL, Inhibitor of Thrombospondin (TSP-1) inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and hepatic fibrosis. LSKL, Inhibitor of Thrombospondin (TSP-1) suppresses subarachnoid fibrosis via inhibition of TSP-1-mediated TGF-β1 activity, prevents the development of chronic hydrocephalus and improves long-term neurocognitive defects following subarachnoid hemorrhage (SAH). LSKL, Inhibitor of Thrombospondin (TSP-1) can readily crosse the blood-brain barrier [1] .
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18
18 Publications Verification
Cat. No.: HY-P0299A
CAS No.: 2828433-17-4
Target:  

TGF-β Receptor

Research Areas:  

Cancer

LSKL, Inhibitor of Thrombospondin (TSP-1) TFA is a latency-associated protein (LAP)-TGFβ derived tetrapeptide and a competitive TGF-β1 antagonist. LSKL, Inhibitor of Thrombospondin (TSP-1) TFA inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and hepatic fibrosis. LSKL, Inhibitor of Thrombospondin (TSP-1) TFA suppresses subarachnoid fibrosis via inhibition of TSP-1-mediated TGF-β1 activity, prevents the development of chronic hydrocephalus and improves long-term neurocognitive defects following subarachnoid hemorrhage (SAH). LSKL, Inhibitor of Thrombospondin (TSP-1) TFA can readily crosse the blood-brain barrier [1] .
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4
4 Cited Publications
Cat. No.: HY-P3970A
Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology

KRFK TFA, a peptide derived from TSP-1, can activate TGF-β. KRFK TFA promotes TGF-β-mediated signaling and its downstream role, independent of thrombospondin (TSP) receptors such as CD47 and CD36. KRFK TFA can be used for chronic ocular surface inflammatory disorders reseach [1].
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2
2 Cited Publications
Cat. No.: HY-P701325
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: THBS1; THBS; Thrombospondin 1; Thrombospondin-1p180; Tsp1; Thrombospondin-1; Tsp; Glycoprotein G; THBS-1; Thrombospondin-P50; Tsp-1; THBS1 Protein
Species:  
Source:  
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2
2 Cited Publications
Cat. No.: HY-P70725
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: THBS1; THBS; Thrombospondin 1; Thrombospondin-1p180; Tsp1; Thrombospondin-1; Tsp; Glycoprotein G; THBS-1; Thrombospondin-P50; Tsp-1; THBS1 Protein
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P83750
Synonyms: Tsp; THBS; Tsp1; Tsp-1; THBS-1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P0301A
Target:  

TGF-β Receptor

Research Areas:  

Cancer

SLLK, Control Peptide for TSP1 Inhibitor (TFA) is a control peptide for LSKL, which is a Thrombospondin (TSP-1) inhibitor.
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Cat. No.: HY-P5322
CAS No.: 138849-26-0
Research Areas:  

Cardiovascular Disease Cancer

Thrombospondin (TSP-1)-derived CD36 binding motif is a bioactive hexapeptide. Thrombospondin (TSP-1)-derived CD36 binding motif interferes with the interaction between cells and the extracellular matrix by binding to CD36 and angiostatin, thereby affecting the cell adhesion and migration process. Thrombospondin (TSP-1)-derived CD36 binding motif inhibits platelet aggregation. Thrombospondin (TSP-1)-derived CD36 binding motif exerts an anti-tumor effect against colon cancer [1] .
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Cat. No.: HY-P0144
CAS No.: 149234-04-8
Target:  

CD47 Apoptosis

Research Areas:  

Inflammation/Immunology

Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide [1].
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Cat. No.: HY-P0301
CAS No.: 2918768-29-1
Target:  

TGF-β Receptor

Research Areas:  

Cancer

SLLK, Control Peptide for TSP1 Inhibitor is a control peptide for LSKL (leucine-serine-lysine-leucine).
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Cat. No.: HY-P3970
CAS No.: 162290-78-0
Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology

KRFK, a peptide derived from TSP-1, can activate TGF-β. KRFK promotes TGF-β-mediated signaling and its downstream role, independent of thrombospondin (TSP) receptors such as CD47 and CD36. KRFK can be used for chronic ocular surface inflammatory disorders reseach [1].
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Cat. No.: HY-P3970D
Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology

KQFK TFA is the TFA salt form of KQFK (HY-P3970C). KQFK TFA is an inactive control of KRFK (HY-P3970). KRFK is a peptide derived from TSP-1 that can activate TGF-β [1].
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Cat. No.: HY-P3996
CAS No.: 945373-85-3
Target:  

Peptides

Research Areas:  

Cancer

Properdistatin is a peptide derived from the thrombospondin 1 (TSP-1) domain of properdin. Properdistatin inhibits angiogenesis and improves vascular function. Properdistatin has the potential for the research of melanoma [1].
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Cat. No.: HY-P11227
Research Areas:  

Neurological Disease

Compound 19A8.8 is a cyclic peptide derived from a CD36 protein fragment. Compound 19A8.8 inhibits the TGF-β/Smad3 signaling pathway by suppressing the interaction between TSP1 and CD36. Compound 19A8.8 has no obvious cytotoxicity. Compound 19A8.8 can be used for research on colon injury and fibrosis [1].
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Cat. No.: HY-P3970C
CAS No.: 162290-88-2
Target:  

TGF-β Receptor

Research Areas:  

Others

KQFK is an inactive control of KRFK (HY-P3970). KRFK is a peptide derived from TSP-1 that can activate TGF-β [1].
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Cat. No.: HY-RS16903
Research Areas:  

Others

Thbs1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Thbs1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P83530
Synonyms: Tsp; THBS; Tsp1; Tsp-1; THBS-1

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse

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Cat. No.: HY-P83530A
Synonyms: Tsp; THBS; Tsp1; Tsp-1; THBS-1

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse

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Cat. No.: HY-182611
CAS No.: 1637468-93-9
Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology Cancer

SRI-31277 is a thrombospondin 1 (TSP-1) inhibitor with a human target pIC50 of 8.28 nM and in vivo activity, and exhibits a very short plasma half-life with intravenous administration.SRI-31277 inhibits interaction between TSP-1 and the latency-associated peptide (LAP) of latent TGF-β, blocking TSP-1-mediated TGF-β activation.SRI-31277 can be used for the research of multiple myeloma and fibrotic conditions [1].
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Cat. No.: HY-RS14479
Research Areas:  

Others

THBS1 Human Pre-designed siRNA Set A contains three designed siRNAs for THBS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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