Properdistatin
Properdistatin is a peptide derived from the thrombospondin 1 (TSP-1) domain of properdin. Properdistatin inhibits angiogenesis and improves vascular function. Properdistatin has the potential for the research of melanoma.
For research use only. We do not sell to patients.
- CAS No.: 945373-85-3
- Formula: C89H149N33O27S2
- Molecular Weight:2177.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Adult female BALB/c nu/nu mice (R-18, A-07, and D-12 human melanoma cells)[1]
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Dosage:80 mg/kg
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Administration:I.p.; daily for 4 days
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Result:Inhibited angiogenesis in human melanoma xenografts with low TSP-1 expression, selectively removed small-diameter capillaries, but did not change the morphology of tumor arterioles or tumor venules, and reduced blood supply times and increased plasma velocities.
Chemical Information
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CAS No. 945373-85-3
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Molecular Weight 2177.47
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Formula C89H149N33O27S2
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Sequence Shortening
GPWEPCSVTCSKGTRTRRR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Properdistatin Related Classifications
HY-P3996 Related Classifications
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