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Results for "

Twist

" in MedChemExpress (MCE) Product Catalog:

20

Inhibitors & Agonists

1

Fluorescent Dyes

1

Biochemical Assay Reagents

3

Natural
Products

4

Antibodies

6

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2013
    Aristolactam I
    1 Publications Verification

    Aristololactam; Aristolactam

    		 Drug Metabolite Aquaporin Cadherin TGF-beta/Smad Endocrinology Cancer
    Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis .
    Aristolactam I
  • HY-119163
    L-902688
    3 Publications Verification

    		 Prostaglandin Receptor Cardiovascular Disease Inflammation/Immunology
    L-902688 is a potent, selective and orally active EP4 receptor agonist with a Ki of 0.38 nM and an EC50 of 0.6 nM. L-902688 shows >4,000-fold selective for EP4 over other EP and prostanoid receptors .
    L-902688
  • HY-152073
    BETA-1

    		Fluorescent Dye Others
    BETA-1 is the first twisted intramolecular charge transfer (TICT)-aggregation-induced emission (AIE) integration molecule. BETA-1 emits cyan fluorescence in lipid droplets (LDs) and red fluorescence in mitochondria. BETA-1 can be used for the simultaneous and dual-color imaging of LDs and mitochondria in vivo and in vitro .
    BETA-1
  • HY-W541025
    Deoxyribonucleic acid

    		Biochemical Assay Reagents Others
    Deoxyribonucleic acid is a polymer formed by two polynucleotide chains twisted around each other to form a double-helix structure. Deoxyribonucleic acid exists in all dividing cells and is a fundamental component of chromosomes .
    Deoxyribonucleic acid
  • HY-N8624
    Ethyl 3,4-dicaffeoylquinate

    		Bacterial Others
    Ethyl 3,4-dicaffeoylquinate is a phenolic acid isolated from G. divaricata. G. divaricata is one of the famous traditional Chinese herbs, usually used for bronchitis, tuberculosis, twisted knot cough, rheumatism, diabetes, etc .
    Ethyl 3,4-dicaffeoylquinate
  • HY-106509
    Velaresol

    BW 12C; 12C79; BW 12C79

    		 Hemoglobin Others
    Velaresol (BW 12C) is a potent left-shifting anti-sickling compound in vitro . Sickle cell disease is an inherited disorder of the hemoglobin molecule. When hemoglobin molecules are exposed to a variety of environments, the red blood cell hemoglobin polymerizes, twists, and morphs into a sickle shape.
    Velaresol
  • HY-RS15281
    TWIST1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TWIST1 Human Pre-designed siRNA Set A contains three designed siRNAs for TWIST1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TWIST1 Human Pre-designed siRNA Set A
    TWIST1 Human Pre-designed siRNA Set A
  • HY-179452
    KRAS G13D-IN-2

    		Ras CDK Mitochondrial Metabolism Cancer
    KRAS G13D-IN-2 (compound 8B) is a potent orally active KRAS G13D inhibitor with IC50 values of 1.95 μM (HCT-116 G13D) and 2.16 μM (HCT-15 G13D). KRAS G13D-IN-2 induces G1-phase arrest and mitochondrial membrane depolarization. KRAS G13D-IN-2 induces senescence through CDK6/TWIST1 inhibition. KRAS G13D-IN-2 inhibits tumor growth in murine models. KRAS G13D-IN-2 can be used for KRAS G13D-mutant colorectal cancer research .
    KRAS G13D-IN-2
  • HY-RS21968
    Twist2 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Twist2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Twist2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Twist2 Mouse Pre-designed siRNA Set A
    Twist2 Mouse Pre-designed siRNA Set A
  • HY-RS15282
    TWIST2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TWIST2 Human Pre-designed siRNA Set A contains three designed siRNAs for TWIST2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TWIST2 Human Pre-designed siRNA Set A
    TWIST2 Human Pre-designed siRNA Set A
  • HY-RS26705
    Twist1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Twist1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Twist1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Twist1 Rat Pre-designed siRNA Set A
    Twist1 Rat Pre-designed siRNA Set A
  • HY-RS20201
    Twist1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Twist1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Twist1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Twist1 Mouse Pre-designed siRNA Set A
    Twist1 Mouse Pre-designed siRNA Set A
  • HY-125630
    Decacyclene

    		Biochemical Assay Reagents Others
    Decacyclene is a large polycyclic aromatic hydrocarbon with a triple symmetry. Decacyclene is a three-blade molecular propeller in the solid state, and crystal structure analysis shows that the molecule has a non-planar twisted form, and the crystal is chiral, which may correspond to the enantiomers of the Decacyclene propeller. Decacyclene can be used for research in chemical synthesis and materials science .
    Decacyclene
  • HY-122125
    RX 336M

    		Drug Derivative Neurological Disease
    RX 336M is a dihydrocodeinone analogue. RX 336M induces behaviors consisting of consisting of behavioral activation, rapid forepaw movements, excessive grooming, and whole body "wet-dog" shakes (WDS) (rapid twisting of the head and trunk with the forepaws leaving the ground). RX 336M can be used for the study of neurological disease .
    RX 336M
  • HY-N2013R
    Aristolactam I (Standard)

    Aristololactam (Standard); Aristolactam (Standard)

    		 Reference Standards Caspase Apoptosis Inflammation/Immunology
    Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis .
    Aristolactam I (Standard)
  • HY-RS28485
    Twist2 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    Twist2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Twist2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Twist2 Rat Pre-designed siRNA Set A
    Twist2 Rat Pre-designed siRNA Set A
  • HY-181492
    Antifungal agent 155 hydrochloride

    		Fungal Infection Inflammation/Immunology
    Antifungal agent 155 hydrochloride is an antifungal agent. Antifungal agent 155 hydrochloride induces bent, twisted, abnormally swollen hyphae, compromises fungal hyphal plasma membrane integrity, and triggers fungal cell death. Antifungal agent 155 hydrochloride can be used for the research of fusarium keratitis .
    Antifungal agent 155 hydrochloride
  • HY-179340
    Antiproliferative agent-74

    		Apoptosis Cancer
    Antiproliferative agent-74 (Compound 19a) is an anti-proliferative agent. Antiproliferative agent-74 suppresses Twist1 expression, induces weak Apoptosis. Antiproliferative agent-74 displays anti-proliferative activity against non-small cell lung cancer cells .
    Antiproliferative agent-74
  • HY-106509R
    Velaresol (Standard)

    BW 12C (Standard); 12C79 (Standard); BW 12C79 (Standard)

    		 Reference Standards Others Others
    Velaresol (Standard) is the analytical standard of Velaresol. This product is intended for research and analytical applications. Velaresol (BW 12C) is a potent left-shifting anti-sickling compound in vitro . Sickle cell disease is an inherited disorder of the hemoglobin molecule. When hemoglobin molecules are exposed to a variety of environments, the red blood cell hemoglobin polymerizes, twists, and morphs into a sickle shape.
    Velaresol (Standard)
  • HY-D3391
    RMR-Tre

    		Bacterial Infection
    RMR-Tre is a fluorescent probe targeting the mycobacterial acyltransferase Ag85. Under the catalysis of Ag85, RMR-Tre undergoes 6-position mycoloylation and anchors to the mycobacterial membrane, while achieving fluorescence activation by inhibiting the intramolecular twisted charge transfer state transition. RMR-Tre can distinguish live mycobacteria from dead ones through metabolism-driven labeling, enabling rapid, wash-free, low-background detection of viable bacteria. RMR-Tre reports the drug resistance of Mycobacterium tuberculosis via the trehalose catalytic shift activity readout associated with TreS. In addition, RMR-Tre can be combined with flow cytometry or high-content imaging techniques to visualize and quantitatively analyze the metabolic heterogeneity of Mycobacterium tuberculosis related to persistence and drug resistance. RMR-Tre is widely used in tuberculosis-related research .
    RMR-Tre

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