6701-66-2
Chemical Structure
RX 336M
- CAS No.: 6701-66-2
- Formula:C24H29NO3
- Molecular Weight:379.49
IUPAC Name: 8-methoxy-3,4,14-trimethyl-1,2,4a,5,12,13,14,15-octahydro-11,15-methanobenzo[i]benzofuro[3,2-e]isoquinolin-6(6aH)-one
InChIKey: FYYHNMMBPNAWGG-UHFFFAOYSA-N
SMILES: O=C1C2OC3=C(C=CC(CC4C5(C6C1)CCC(C)=C6C)=C3C25CCN4C)OC
Biological Activity: RX 336M is a dihydrocodeinone analogue. RX 336M induces behaviors consisting of consisting of behavioral activation, rapid forepaw movements, excessive grooming, and whole body "wet-dog" shakes (WDS) (rapid twisting of the head and trunk with the forepaws leaving the ground). RX 336M can be used for the study of neurological disease[1][2].
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RX 336M | RX 336M is a dihydrocodeinone analogue. RX 336M induces behaviors consisting of consisting of behavioral activation, rapid forepaw movements, excessive grooming, and whole body "wet-dog" shakes (WDS) (rapid twisting of the head and trunk with the forepaws leaving the ground). RX 336M can be used for the study of neurological disease. | |||||||||||||||||||||
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- [1]. Lee EJ, et al. Discovery of a Novel Potent EGFR Inhibitor Against EGFR Activating Mutations and On-Target Resistance in NSCLC. Clin Cancer Res. 2024 Apr 15;30(8):1582-1594. [Content Brief]
- [2]. Isaacson RL, et al. Age- and sex-related induction of excessive grooming and "wet-dog" shakes by the codeinone RX 336-M in the rat. Behav Neural Biol. 1987 May;47(3):250-61. [Content Brief]
Keywords
