17 Results for "

VV

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "VV" in MCE Product Catalog:

19
19 Publications Verification
Cat. No.: HY-B0502A
CAS No.: 93106-59-3
Synonyms: BAY Vp 2674 monohydrochloride; PD160788 monohydrochloride
Research Areas:  

Infection

Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis. Enrofloxacin monohydrochloride shows inhibitory activity against vaccinia virus (VV).
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13
13 Cited Publications
Cat. No.: HY-B0125
CAS No.: 82419-36-1
Synonyms: Hoe-280
Ofloxacin (Hoe-280) is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase. Ofloxacin shows inhibitory activity against vaccinia virus (VV).
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1
1 Cited Publications
Cat. No.: HY-107931
CAS No.: 57-57-8
Purity:  99.36%
Synonyms: β-propiolactone; 2-Oxetanone; Betaprone
Research Areas:  

Infection

Propiolactone (β-propiolactone; 2-Oxetanone) is a viral chemical inactivator that causes the infectious inactivation of viruses. Propiolactone was co-incubated with SARS-CoV at a ratio of 1:1000 (v:v) and used as a bacteriostatic agent to formulate the BPL-inactivated influenza virus vaccine (Flu-BPL) .
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Cat. No.: HY-145119AS
CAS No.: 2779498-79-0
Purity:  99.46%
Synonyms: VV116; GS-621763-d1 hydrobromide
Mindeudesivir (JT001; VV116; GS-621763-d1) hydrobromide is a deuterated version of Remdesivir (HY-104077), a highly orally active nucleoside antiviral against SARS-CoV-2 and respiratory syncytial virus (RSV). Mindeudesivir hydrobromide retains the antiviral activity of Remdesivir against COVID-19, and is the first domestically produced deuterium targeting the COVID-19 .
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Cat. No.: HY-160957
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Cap A (Acetonitrile/Acetic Anhydride, 80/20 v/v) is a capping reagent that can be used in DNA/RNA synthesis .
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Cat. No.: HY-172918
CAS No.: 3003864-86-3
Research Areas:  

Infection

VV261 is an orally active prodrug of 4'-fluorouridine. VV261 inhibits viral RNA-dependent RNA polymerase. VV261 exhibits antiviral activity against CCHFV, SFTSV and LCMV. VV261 can be used in research related to viral infections .
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Cat. No.: HY-Y1890B
CAS No.: 61791-12-6
Cremophor EL-10 is a nonionic polyoxyethylene castor oil surfactant with multiple functions including organic solubilizer, mixed zinc anode corrosion inhibitor and dendrite growth inhibitor. By forming a physical barrier to block electrolyte contact and constructing oriented hydration channels to reduce the desolvation energy barrier of Zn 2+ , Cremophor EL-10 achieves a corrosion inhibition efficiency of over 99%. Cremophor EL-10 exerts no significant effects on the mitochondrial activity and cell viability of epithelial cells, making it suitable for in vitro drug delivery and biopharmaceutical research at concentrations ≤10% v/v. However, Cremophor EL-10 may induce sustained non-endothelium-dependent contraction in rat aortic rings and exert concentration-dependent inhibitory effects on acetylcholine-induced endothelium-dependent relaxation responses .
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Cat. No.: HY-B0125R
CAS No.: 82419-36-1
Synonyms: Hoe-280 (Standard)
Ofloxacin (Standard) is the analytical standard of Ofloxacin. This product is intended for research and analytical applications. Ofloxacin (Hoe-280) is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase. Ofloxacin shows inhibitory activity against vaccinia virus (VV).
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Cat. No.: HY-P5364
CAS No.: 848642-31-9
Target:  

Peptides

Research Areas:  

Others

B8R 20-27 is a biological active peptide. (This is amino acids 20 to 27 fragment of B8R, a vaccinia virus (VV) gene that encodes a secreted protein related to gamma interferon receptor. B8R binding to IFN-g neutralizes its antiviral activity.)
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Cat. No.: HY-145119S
CAS No.: 2647442-33-7
Purity:  99.02%
Synonyms: VV116 free base; GS-621763-d1
GS-621763-d1 is the deuterium labeled GS-621763 (HY-145119) . GS-621763, an orally bioavailable proagent of GS-441524, shows antiviral activity against SARS-CoV-2 pathogenesis in mice .
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Cat. No.: HY-149023
CAS No.: 2490468-39-6
Target:  

HSV

Research Areas:  

Infection

HSV-1/HSV-2-IN-2 is a HSV-1, HSV-2 and VV inhibitor with EC50 values of 6.8, 8.9 and 8.9 µM, respectively.
HSV-1/HSV-2-IN-2 shows antiviral activity .
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Cat. No.: HY-106685
CAS No.: 83705-13-9
Synonyms: CI 935
Target:  

Influenza Virus

Research Areas:  

Infection

Selenazofurin is an antiviral compound used against influenza A and influenza B viruses. Selenazofurin shows antiviral activity in cells against Measles, Para-3, Mumps, VV, HSV-2 with the ED50s of 3.7 μg/ml, 1.3 μg/ml, 8.0 μg/ml, 3.4 μg/ml, 4.3 μg/ml .
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Cat. No.: HY-RS16365
Research Areas:  

Others

VV Human Pre-designed siRNA Set A contains three designed siRNAs for VV gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-B0502AR
CAS No.: 93106-59-3
Synonyms: BAY Vp 2674 monohydrochloride (Standard); PD160788 monohydrochloride (Standard)
Enrofloxacin (monohydrochloride) (Standard) is the analytical standard of Enrofloxacin (monohydrochloride). This product is intended for research and analytical applications. Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis. Enrofloxacin monohydrochloride shows inhibitory activity against vaccinia virus (VV).
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Cat. No.: HY-107931R
CAS No.: 57-57-8
Synonyms: β-propiolactone (Standard); 2-Oxetanone (Standard); Betaprone (Standard)
Research Areas:  

Infection

Propiolactone (Standard) is the analytical standard of Propiolactone. This product is intended for research and analytical applications. Propiolactone (β-propiolactone; 2-Oxetanone) is a viral chemical inactivator that causes the infectious inactivation of viruses. Propiolactone was co-incubated with SARS-CoV at a ratio of 1:1000 (v:v) and used as a bacteriostatic agent to formulate the BPL-inactivated influenza virus vaccine (Flu-BPL) .
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Cat. No.: HY-148914
CAS No.: 57344-98-6
Target:  

DNA Methyltransferase

Research Areas:  

Infection

(S)-Tubercidinylhomocysteine (Page 46) is a potent inhibitor of S-adenosylmethionine-dependent methyltransferase. (S)-Tubercidinylhomocysteine can be used for the study of herpesviruses (HSV) and vaccinia (VV).
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Cat. No.: HY-L127
38 compounds

Orthopoxvirus is a genus of viruses in the family Poxviridae and subfamily Chordopoxvirinae. The orthopoxvirus genus consists of 12 viruses including variola virus, vaccinia virus (VV), cowpox viruses (CV), monkeypox virus, and camelpox virus. Smallpox has been eradicated worldwide in 1980, but some other orthopoxvirus, such as monkeypox virus, are still threats to human health.

There are not many drugs available for orthopoxvirus treatment. The only product currently available for treatment of complications of Orthopoxvirus infection is vaccinia immunoglobulin (VIG). In 2021, brincidofovir was approved by FDA for the treatment of smallpox and tecovirimat was approved by EMA for the treatment of monkeypox in 2022. A few active compounds including interferon and interferon inducers, and a variety of nucleosides or nucleotides have been reported to have activity against orthopoxvirus.

MCE carefully prepared a unique collection of 38 compounds reported with the anti- orthopoxvirus activity which can be used for drug screening and other research about orthopoxvirus.

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