Selenazofurin
Selenazofurin is an antiviral compound used against influenza A and influenza B viruses. Selenazofurin shows antiviral activity in cells against Measles, Para-3, Mumps, VV, HSV-2 with the ED50s of 3.7 μg/ml, 1.3 μg/ml, 8.0 μg/ml, 3.4 μg/ml, 4.3 μg/ml.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 83705-13-9
- 分子式: C9H12N2O5Se
- 分子量:307.16
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 5637 | IC50 |
2.3 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against 5637, human bladder carcinoma cell line
Compound was tested for antiproliferative activity against 5637, human bladder carcinoma cell line
|
[PMID: 9171883] |
| ACHN | IC50 |
13.8 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against ACHN, human renal adenocarcinoma
Compound was tested for antiproliferative activity against ACHN, human renal adenocarcinoma
|
[PMID: 9171883] |
| CCRF-CEM | IC50 |
1.2 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against CCRF-CEM, human acute T-lymphoblastic leukemia
Compound was tested for antiproliferative activity against CCRF-CEM, human acute T-lymphoblastic leukemia
|
[PMID: 9171883] |
| CCRF-SB | IC50 |
1.5 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against CCRF-SB, human acute B-lymphoblastic leukemia
Compound was tested for antiproliferative activity against CCRF-SB, human acute B-lymphoblastic leukemia
|
[PMID: 9171883] |
| CHO-K1 | IC50 |
0.6 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against CHO-K1, Chinese hamster ovary
Compound was tested for antiproliferative activity against CHO-K1, Chinese hamster ovary
|
[PMID: 9171883] |
| HeLa | IC50 |
7.9 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against HeLa, human cervix carcinoma
Compound was tested for antiproliferative activity against HeLa, human cervix carcinoma
|
[PMID: 9171883] |
| HT-29 | IC50 |
7.7 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against HT29, human colon adenocarcinoma
Compound was tested for antiproliferative activity against HT29, human colon adenocarcinoma
|
[PMID: 9171883] |
| K562 | IC50 |
0.5 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against K562, human erythroid leukemia
Compound was tested for antiproliferative activity against K562, human erythroid leukemia
|
[PMID: 9171883] |
| L1210 | IC50 |
0.5 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against L1210, murine lymphocytic leukemia
Compound was tested for antiproliferative activity against L1210, murine lymphocytic leukemia
|
[PMID: 9171883] |
| MOLT-4 | IC50 |
0.6 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against MOLT-4, human acute T-lymphoblastic leukemia
Compound was tested for antiproliferative activity against MOLT-4, human acute T-lymphoblastic leukemia
|
[PMID: 9171883] |
| Raji | IC50 |
1.6 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against Raji, human Burkitt lymphoma
Compound was tested for antiproliferative activity against Raji, human Burkitt lymphoma
|
[PMID: 9171883] |
| Vero | ED50 |
1.4 x 10-5M
Compound: Selenazofurin
|
In vitro antiviral activity against herpes simplex virus type 2 virus was evaluated.
In vitro antiviral activity against herpes simplex virus type 2 virus was evaluated.
|
[PMID: 4020823] |
| Vero | ED50 |
3.2 x 10-6M
Compound: Selenazofurin
|
In vitro antiviral activity against measles virus was evaluated.
In vitro antiviral activity against measles virus was evaluated.
|
[PMID: 4020823] |
| Vero | ED50 |
3.2 x 10-6M
Compound: Selenazofurin
|
In vitro antiviral activity against Parainfluenza type 3 was evaluated.
In vitro antiviral activity against Parainfluenza type 3 was evaluated.
|
[PMID: 4020823] |
| Vero | ED50 |
9.8 x 10-6M
Compound: Selenazofurin
|
In vitro antiviral activity against vaccinia virus was evaluated.
In vitro antiviral activity against vaccinia virus was evaluated.
|
[PMID: 4020823] |
| WIL2-NS | IC50 |
1.2 μM
Compound: Selenazofurin
|
Compound was tested for antiproliferative activity against Wil2-NS, human splenic lymphoblastoid cells
Compound was tested for antiproliferative activity against Wil2-NS, human splenic lymphoblastoid cells
|
[PMID: 9171883] |
化学情報
-
CAS 番号 83705-13-9
-
分子量 307.16
-
分子式 C9H12N2O5Se
-
SMILES
O[C@H]1[C@@H](O)[C@H](C2=NC(C(N)=O)=C[Se]2)O[C@@H]1CO
-
別名
CI 935
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)