2. Anti-infection
  3. Influenza Virus
  4. Selenazofurin

Selenazofurin is an antiviral compound used against influenza A and influenza B viruses. Selenazofurin shows antiviral activity in cells against Measles, Para-3, Mumps, VV, HSV-2 with the ED50s of 3.7 μg/ml, 1.3 μg/ml, 8.0 μg/ml, 3.4 μg/ml, 4.3 μg/ml.

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Selenazofurin

Selenazofurin Chemical Structure

CAS No. : 83705-13-9

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Selenazofurin Related Antibodies

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Description

Selenazofurin is an antiviral compound used against influenza A and influenza B viruses. Selenazofurin shows antiviral activity in cells against Measles, Para-3, Mumps, VV, HSV-2 with the ED50s of 3.7 μg/ml, 1.3 μg/ml, 8.0 μg/ml, 3.4 μg/ml, 4.3 μg/ml[1].

Cellular Effect
Cell Line Type Value Description References
5637 IC50
2.3 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against 5637, human bladder carcinoma cell line
Compound was tested for antiproliferative activity against 5637, human bladder carcinoma cell line
[PMID: 9171883]
ACHN IC50
13.8 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against ACHN, human renal adenocarcinoma
Compound was tested for antiproliferative activity against ACHN, human renal adenocarcinoma
[PMID: 9171883]
CCRF-CEM IC50
1.2 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against CCRF-CEM, human acute T-lymphoblastic leukemia
Compound was tested for antiproliferative activity against CCRF-CEM, human acute T-lymphoblastic leukemia
[PMID: 9171883]
CCRF-SB IC50
1.5 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against CCRF-SB, human acute B-lymphoblastic leukemia
Compound was tested for antiproliferative activity against CCRF-SB, human acute B-lymphoblastic leukemia
[PMID: 9171883]
CHO-K1 IC50
0.6 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against CHO-K1, Chinese hamster ovary
Compound was tested for antiproliferative activity against CHO-K1, Chinese hamster ovary
[PMID: 9171883]
HT-29 IC50
7.7 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against HT29, human colon adenocarcinoma
Compound was tested for antiproliferative activity against HT29, human colon adenocarcinoma
[PMID: 9171883]
HeLa IC50
7.9 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against HeLa, human cervix carcinoma
Compound was tested for antiproliferative activity against HeLa, human cervix carcinoma
[PMID: 9171883]
K562 IC50
0.5 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against K562, human erythroid leukemia
Compound was tested for antiproliferative activity against K562, human erythroid leukemia
[PMID: 9171883]
L1210 IC50
0.5 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against L1210, murine lymphocytic leukemia
Compound was tested for antiproliferative activity against L1210, murine lymphocytic leukemia
[PMID: 9171883]
MOLT-4 IC50
0.6 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against MOLT-4, human acute T-lymphoblastic leukemia
Compound was tested for antiproliferative activity against MOLT-4, human acute T-lymphoblastic leukemia
[PMID: 9171883]
Raji IC50
1.6 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against Raji, human Burkitt lymphoma
Compound was tested for antiproliferative activity against Raji, human Burkitt lymphoma
[PMID: 9171883]
Vero ED50
3.2 x 10-6 M
Compound: Selenazofurin
In vitro antiviral activity against Parainfluenza type 3 was evaluated.
In vitro antiviral activity against Parainfluenza type 3 was evaluated.
[PMID: 4020823]
Vero ED50
1.4 x 10-5 M
Compound: Selenazofurin
In vitro antiviral activity against herpes simplex virus type 2 virus was evaluated.
In vitro antiviral activity against herpes simplex virus type 2 virus was evaluated.
[PMID: 4020823]
Vero ED50
3.2 x 10-6 M
Compound: Selenazofurin
In vitro antiviral activity against measles virus was evaluated.
In vitro antiviral activity against measles virus was evaluated.
[PMID: 4020823]
Vero ED50
9.8 x 10-6 M
Compound: Selenazofurin
In vitro antiviral activity against vaccinia virus was evaluated.
In vitro antiviral activity against vaccinia virus was evaluated.
[PMID: 4020823]
WIL2-NS IC50
1.2 μM
Compound: Selenazofurin
Compound was tested for antiproliferative activity against Wil2-NS, human splenic lymphoblastoid cells
Compound was tested for antiproliferative activity against Wil2-NS, human splenic lymphoblastoid cells
[PMID: 9171883]
Molecular Weight

307.16

Formula

C9H12N2O5Se
CAS No.
SMILES

O[C@H]1[C@@H](O)[C@H](C2=NC(C(N)=O)=C[Se]2)O[C@@H]1CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Selenazofurin Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Selenazofurin83705-13-9CI 935CI935CI-935Influenza VirusInhibitorinhibitorinhibit

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