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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
72 Results for "
acid-sensitive
" in MedChemExpress (MCE) Product Catalog:
Products (72)
72 Results for "acid-sensitive" in MCE Product Catalog:
42
42 Publications Verification
Cat. No.: HY-P0014
CAS No.: 204656-20-2
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Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
42
42 Publications Verification
Cat. No.: HY-P0014B
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6
6 Cited Publications
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ML365 is a selective two-pore domain potassium channel KCNK3/TASK1 inhibitor, with an IC50 of 4 nM. ML365 acts as a pharmacological tool that can be used to examine the specific roles of TASK1 channels .
5
5 Cited Publications
Cat. No.: HY-16261B
CAS No.: 480998-12-7
Synonyms: (E/Z)-Aldoxorubicin hydrochloride; Doxorubicin(6-maleimidocaproyl)hydrazone hydrochloride
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MC-DOXHZN ((E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone) hydrochloride is an albumin-binding proagent of Doxorubicin (HY-15142A) (DNA topoisomerase II inhibitor), with acid-sensitive properties. MC-DOXHZN hydrochloride can be used to synthesize ADC .
3
3 Cited Publications
Cat. No.: HY-P3462
CAS No.: 1415456-99-3
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3
Category:
Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
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3
3 Cited Publications
Cat. No.: HY-P3462A
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1
Research Areas:
Methotrexate metabolite (DAMPA) is an active metabolite of Methotrexate. Methotrexate is a Folic acid (HY-16637) antagonist, widely used as an immunosuppressant. Methotrexate metabolite is an antimalarial agent that inhibits parasite growth under physiological folic acid conditions, with IC50 values of 446 nM and 812 nM against folic acid-sensitive strains and highly resistant strains, respectively. Methotrexate metabolite exhibits pharmacokinetic characteristics of rapid clearance and extensive metabolism, with a mean clearance rate of 1.9 l/kg/h and a mean terminal half-life of 51 minutes. Methotrexate metabolite is promising for research in the field of inflammation .
1
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1
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1
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1
1 Cited Publications
Cat. No.: HY-P10218
CAS No.: 479482-23-0
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P10218A
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P10869
Research Areas:
Cat. No.: HY-P10272
CAS No.: 1628323-80-7
Synonyms: PTG-300
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Cat. No.: HY-W019358
CAS No.: 612-20-4
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A2793 is an efficient dual TWIK-related acid-sensitive K + channel (TASK)-1/TRESK inhibitor, with an IC50 of 6.8 μM for mTRESK. A2764 is more selective for TRESK, and it only moderately influences TREK-1 and TALK-1 .
Cat. No.: HY-P0014S1
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Cat. No.: HY-P10271
Synonyms: NNC0090-2746; MAR709; RO6811135
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Cat. No.: HY-P10031
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
