36 Results for "

anaphylatoxin

" in MedChemExpress (MCE) Product Catalog:
Products (36)

36 Results for "anaphylatoxin" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-106178
CAS No.: 219639-75-5
Purity:  99.98%
Synonyms: 3D53
PMX-53 (3D53) is a synthetic peptidic and a potent and orally active complement C5a receptor (CD88) antagonist with an IC50 of 20 nM. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation. PMX-53 specifically binds to C5aR1 and does not bind to the second C5aR (C5L2) and C3aR. PMX-53 has anti-inflammatory, anticancer and antiatherosclerotic effects .
loading...
    loading...
8
8 Cited Publications
Cat. No.: HY-P7863
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C3; Complement Component 3; Complement C3; C3a anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:  
Source:  
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-P7695
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement C5; C5a anaphylatoxin; CPAMD4; Prepro-C5; Complement Component 5; anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Source:  
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-16992A
CAS No.: 405098-33-1
W-54011 is a potent and orally active non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM. W-54011 also inhibits C5a-induced intracellular Ca 2+ mobilization, chemotaxis, and generation of ROS in human neutrophils with IC50s of 3.1 nM, 2.7 nM, and 1.6 nM, respectively .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-P7862
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C3; Complement Component 3; Complement C3; C3a anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:  
Source:  
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P0171
CAS No.: 664334-36-5
Synonyms: BKT140 (4-fluorobenzoyl); BL-8040; TF14016
Target:  

CXCR

Research Areas:  

Endocrinology Cancer

Motixafortide (BKT140 4-fluorobenzoyl) is a novel CXCR4 antagonist with an IC50 vakue of ~1 nM.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P0009A
CAS No.: 145672-81-7
Synonyms: SB-75 acetate
Target:  

GnRH Receptor Apoptosis

Research Areas:  

Endocrinology

Cetrorelix (SB-75) acetate is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix acetate inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix acetate prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix acetate is applicable for fertility assistance research .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P4452
CAS No.: 209006-18-8
Research Areas:  

Endocrinology

PRL 2915 is a potent human somatostatin subtype 2 receptor (hsst2) antagonist with a Ki of 12 nM .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P7864
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement C5; C5a anaphylatoxin; CPAMD4; Prepro-C5; Complement Component 5; anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P700862
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement C5; C5a anaphylatoxin; CPAMD4; Prepro-C5; Complement Component 5; anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P4971
CAS No.: 1816940-05-2
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

C5a Anaphylatoxin (human) is a pro-inflammatory peptide and a leukocyte chemoattractant. C5a Anaphylatoxin (human) can be used to study inflammation and immunity, such as allergic asthma .
loading...
    loading...
Cat. No.: HY-P0009B
CAS No.: 130143-01-0
Synonyms: SB-75 diacetate
Target:  

GnRH Receptor

Research Areas:  

Neurological Disease Endocrinology

Cetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM .
loading...
    loading...
Cat. No.: HY-131374
CAS No.: 368874-31-1
Target:  

CXCR

Research Areas:  

Cancer

TN14003 is a CXCR4 inhibitor. TN14003 has antitumor activity .
loading...
    loading...
Cat. No.: HY-P5509
CAS No.: 230968-98-6
Target:  

Peptides

Research Areas:  

Others

C5aR1 antagonist peptide is a biological active peptide. (This linear peptide is derived from the C-terminus of the chemokine, complement fragment 5 anaphylatoxin (C5a). This peptide functions to inhibit C5a binding and function at human and rat C5a receptors. C5a is crucial to triggering cellular immune responses and its overexpression is involved in arthritis, Alzheimer’s disease, cystic fibrosis, systemic lupus erythematosus, and other immunoinflammatory diseases.)
loading...
    loading...
Cat. No.: HY-P75332
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C3; Complement Component 3; Complement C3; C3a anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P71719
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement C5; C5a anaphylatoxin; CPAMD4; Prepro-C5; Complement Component 5; anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Pig
Source:  
loading...
    loading...
Cat. No.: HY-P700398
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: C5AR1; C5a-R; Prev. C5R1; C5a anaphylatoxin Chemotactic Receptor; C5AR; C5a anaphylatoxin Receptor; CD88; CD88 Antigen; C5A; C5a Ligand; C5a anaphylatoxin Chemotactic Receptor 1; C5aR; Complement Component 5a Receptor 1; Complement C5a Receptor 1; Complem
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78595
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement C5; C5a anaphylatoxin; CPAMD4; Prepro-C5; Complement Component 5; anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P7695A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement C5; C5a anaphylatoxin; CPAMD4; Prepro-C5; Complement Component 5; anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P704326
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement C5; C5a anaphylatoxin; CPAMD4; Prepro-C5; Complement Component 5; anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:  
Source:  
loading...
    loading...