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antitussive agent

" in MedChemExpress (MCE) Product Catalog:

34

Inhibitors & Agonists

2

Biochemical Assay Reagents

3

Natural
Products

4

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1551
    Benzonatate

    Benzononatine

    		 Sodium Channel Neurological Disease
    Benzonatate (Benzononatine) is an orally active and non-narcotic peripheral antitussive agent. Benzonatate is a reversible voltage-gated Na + channels inhibitor. Benzonatate dampens the activity of cough stretch receptors .
    Benzonatate
  • HY-121388
    Ledol

    (+)-Ledol

    		 Fungal Infection
    Ledol ((+)-Ledol) is an antifungal agent isolated from the volatile oil components of Rhododendron tomentosum. Ledol also acts as an expectorant and antitussive, while it can cause adverse reactions such as dizziness, nausea and vomiting .
    Ledol
  • HY-B1895
    Levodropropizine

    (S)-(-)-Dropropizine; DF-526

    		 Histamine Receptor Neurological Disease Inflammation/Immunology Endocrinology
    Levodropropizine (DF-526) is an orally active histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive agent .
    Levodropropizine
  • HY-B1038
    L-Cysteine methyl ester hydrochloride

    		Endogenous Metabolite Inflammation/Immunology
    L-Cysteine methyl ester hydrochloride is an antitussive, phlegmolytic agent used to relieve breathing difficulties caused by large amounts of phlegm. L-Cysteine methyl ester hydrochloride is a copper corrosion inhibitor used in various industrial studies .
    L-Cysteine methyl ester hydrochloride
  • HY-134004
    Pentoxyverine

    Carbetapentane

    		 Sigma Receptor mAChR Neurological Disease Inflammation/Immunology
    Pentoxyverine (Carbetapentane) is an orally active sigma-1 receptor agonist, with Kis of 41 nM, 894 nM and 75 nM for σ1, σ2 and guinea-pig brain membran σ1, respectively. Pentoxyverine is a muscarinic antagonist. Pentoxyverine is a potent antitussive, anticonvulsant, and spasmolytic agent. Pentoxyverine can be used for inhibiting bronchial interceptor, weakening of cough reflex, bronchial smooth muscle relaxation and reduction of airway resistance .
    Pentoxyverine
  • HY-B1055
    Pentoxyverine citrate

    Carbetapentane citrate

    		 Sigma Receptor mAChR Neurological Disease Inflammation/Immunology
    Pentoxyverine (Carbetapentane) citrate is an orally active and blood-brain barrier permeability sigma-1 receptor agonist, with Kis of 41 nM, 894 nM and 75 nM for σ1, σ2 and guinea-pig brain membrane σ1, respectively. Pentoxyverine citrate is a muscarinic antagonist. Pentoxyverine citrate is a potent antitussive, anticonvulsant, and spasmolytic agent. Pentoxyverine citrate can be used for inhibiting bronchial interceptor, weakening of cough reflex, bronchial smooth muscle relaxation and reduction of airway resistance .
    Pentoxyverine citrate
  • HY-A0161A
    Chlophedianol hydrochloride

    Clofedanol hydrochloride; Calmotusin hydrochloride; NSC 113595 hydrochloride

    		 Others Infection
    Chlophedianol (Clofedanol) hydrochloride is an orally active and potent antitussive agent. Chlophedianol hydrochloride can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
    Chlophedianol hydrochloride
  • HY-118545
    Butamirate

    		STAT Inflammation/Immunology Cancer
    Butamirate is an orally active antitussive agent that acts centrally through the receptors in the brainstem. Butamirate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect. Butamirate inhibits glioblastoma (GBM) growth and STAT3 activity. Butamirate can be used for the study of glioblastoma .
    Butamirate
  • HY-118545A
    Butamirate citrate

    		STAT Inflammation/Immunology Cancer
    Butamirate citrate is an orally active antitussive agent that acts centrally through the receptors in the brainstem. Butamirate citrate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect. Butamirate citrate inhibits glioblastoma (GBM) growth and STAT3 activity. Butamirate citrate can be used for the study of glioblastoma .
    Butamirate citrate
  • HY-B1895R
    Levodropropizine (Standard)

    (S)-(-)-Dropropizine (Standard); DF-526 (Standard)

    		 Reference Standards Histamine Receptor Neurological Disease Inflammation/Immunology Endocrinology
    Levodropropizine (Standard) is the analytical standard of Levodropropizine. This product is intended for research and analytical applications. Levodropropizine (DF-526) is an orally active histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive agent .
    Levodropropizine (Standard)
  • HY-B1032R
    Dropropizine (Standard)

    (±)-Dropropizine (Standard); UCB-196 (Standard)

    		 Others Reference Standards Neurological Disease
    Dropropizine (Standard) is the analytical standard of Dropropizine. This product is intended for research and analytical applications. Dropropizine ((±)-Dropropizine) is a peripheral antitussive agent that acts by inhibiting cough reflex through its action on the peripheral receptors and their afferent conductors .
    Dropropizine (Standard)
  • HY-N10824
    2,3,5,6-Tetramethoxyaporphine

    		Others Others
    2,3,5,6-Tetramethoxyaporphine is an antitussive agent, a medicinally valuable benzyl isoquinoline alkaloid. 2,3,5,6-Tetramethoxyaporphine can be isolated from the yellow hornpoppy, Glaucium flavum Cr. (Fam. Papaveraceae) .
    2,3,5,6-Tetramethoxyaporphine
  • HY-118545AR
    Butamirate citrate (Standard)

    		Reference Standards STAT Inflammation/Immunology Cancer
    Butamirate citrate (Standard) is the analytical standard of Butamirate citrate (HY-118545A). This product is intended for research and analytical applications. Butamirate citrate is an orally active antitussive agent that acts centrally through the receptors in the brainstem. Butamirate citrate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect. Butamirate citrate inhibits glioblastoma (GBM) growth and STAT3 activity. Butamirate citrate can be used for the study of glioblastoma .
    Butamirate citrate (Standard)
  • HY-101828
    Guaiapate

    Klamar; Mg 5454

    		 Others Inflammation/Immunology
    Guaiapate is an antitussive agent.
    Guaiapate
  • HY-B1895S
    Levodropropizine-d8

    (S)-(-)-Dropropizine-d8; DF-526-d8

    		 Isotope-Labeled Compounds Histamine Receptor Inflammation/Immunology Endocrinology
    Levodropropizine-d8 is deuterium labeled Levodropropizine. Levodropropizine (DF-526) is a histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive agent.
    Levodropropizine-d8
  • HY-114723
    NPD9948

    		DNA/RNA Synthesis Others
    NPD9948 is an antitussive agent with antitussive activity in a guinea pig antitussive test. Its half antitussive dose (AtD50) is 14.5 mg/kg and 22.6 mg/kg when injected intraperitoneally and orally, respectively.
    NPD9948
  • HY-121644
    Viminol

    		Opioid Receptor Neurological Disease
    Viminol is a centrally acting analgesic agent. Viminol also shows antitussive activity .
    Viminol
  • HY-106495
    Vadocaine

    OR K-242

    		 Adrenergic Receptor Neurological Disease
    Vadocaine (OR K-242), an orally active antitussive compound, is a local agent that can suppress or relieve pain .
    Vadocaine
  • HY-128418
    Benzonatate (PEGn)

    		Sodium Channel Neurological Disease Inflammation/Immunology
    Benzonatate (PEGn) is a unique non-narcotic antitussive agent that has sodium channel-blocking properties and anesthetic effects on the respiratory stretch receptors .
    Benzonatate (PEGn)
  • HY-A0161
    Chlophedianol

    Clofedanol; Calmotusin; NSC 113595

    		 Others Infection
    Chlophedianol (Clofedanol) is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
    Chlophedianol
  • HY-W354753
    Homatropine hydrochloride

    		mAChR Others
    Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs .
    Homatropine hydrochloride
  • HY-B1895S1
    Levodropropizine-d5

    (S)-(-)-Dropropizine-d5; DF-526-d5

    		 Isotope-Labeled Compounds Histamine Receptor Neurological Disease Inflammation/Immunology Endocrinology
    Levodropropizine-d5 ((S)-(-)-Dropropizine-d5) is deuterium labeled Levodropropizine. Levodropropizine (DF-526) is an orally active histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive agent .
    Levodropropizine-d5
  • HY-A0161AR
    Chlophedianol hydrochloride (Standard)

    Clofedanol hydrochloride (Standard); Calmotusin hydrochloride (Standard); NSC 113595 hydrochloride (Standard)

    		 Sigma Receptor Reference Standards Infection
    Chlophedianol (hydrochloride) (Standard) is the analytical standard of Chlophedianol (hydrochloride). This product is intended for research and analytical applications. Chlophedianol (Clofedanol) hydrochloride is an orally active and potent antitussive agent. Chlophedianol hydrochloride can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
    Chlophedianol hydrochloride (Standard)
  • HY-A0161S
    Chlophedianol-13C6

    Clofedanol-13C6; Calmotusin-13C6; NSC 113595-13C6

    		 Isotope-Labeled Compounds Infection
    Chlophedianol- 13C6 is the 13C labeled Chlophedianol (HY-A0161). Chlophedianol is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
    Chlophedianol-13C6
  • HY-B0535R
    Ethambutol (Standard)

    		Reference Standards Bacterial Antibiotic Infection
    Homatropine (hydrochloride) (Standard) is the analytical standard of Homatropine (hydrochloride). This product is intended for research and analytical applications. Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs .
    Ethambutol (Standard)
  • HY-W767656
    Dropropizine-d4

    (±)-Dropropizine-d4; UCB-196-d4

    		 Isotope-Labeled Compounds Others Neurological Disease
    Dropropizine-d4 ((±)-Dropropizine-d4) is deuterium labeled Dropropizine. Dropropizine ((±)-Dropropizine) belongs to the phenylpiperazine group of organic compounds. Dropropizine is a peripheral antitussive agent that acts by inhibiting cough reflex through its action on the peripheral receptors and their afferent conductors .
    Dropropizine-d4
  • HY-W354753R
    Homatropine hydrochloride (Standard)

    		mAChR Reference Standards Others
    Homatropine (hydrochloride) (Standard) is the analytical standard of Homatropine (hydrochloride). This product is intended for research and analytical applications. Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs .
    Homatropine hydrochloride (Standard)
  • HY-B1551R
    Benzonatate (Standard)

    Benzononatine (Standard)

    		 Reference Standards Sodium Channel Neurological Disease
    Benzonatate (Standard) (Benzononatine (Standard)) is the analytical standard of Benzonatate (HY-B155). This product is intended for research and analytical applications. Benzonatate (Benzononatine) is an orally active and non-narcotic peripheral antitussive agent. Benzonatate is a reversible voltage-gated Na + channels inhibitor. Benzonatate dampens the activity of cough stretch receptors.
    Benzonatate (Standard)
  • HY-134004R
    Pentoxyverine (Standard)

    Carbetapentane (Standard)

    		 Reference Standards Sigma Receptor mAChR Neurological Disease Inflammation/Immunology
    Pentoxyverine (Standard) is the analytical standard of Pentoxyverine. This product is intended for research and analytical applications. Pentoxyverine (Carbetapentane) is an orally active sigma-1 receptor agonist, with Kis of 41 nM, 894 nM and 75 nM for σ1, σ2 and guinea-pig brain membran σ1, respectively. Pentoxyverine is a muscarinic antagonist. Pentoxyverine is a potent antitussive, anticonvulsant, and spasmolytic agent. Pentoxyverine can be used for inhibiting bronchial interceptor, weakening of cough reflex, bronchial smooth muscle relaxation and reduction of airway resistance .
    Pentoxyverine (Standard)
  • HY-B1055R
    Pentoxyverine citrate (Standard)

    Carbetapentane citrate (Standard)

    		 Reference Standards Sigma Receptor mAChR Neurological Disease Inflammation/Immunology
    Pentoxyverine (citrate) (Standard) is the analytical standard of Pentoxyverine (citrate). This product is intended for research and analytical applications. Pentoxyverine (Carbetapentane) citrate is an orally active sigma-1 receptor agonist, with Kis of 41 nM, 894 nM and 75 nM for σ1, σ2 and guinea-pig brain membrane σ1, respectively. Pentoxyverine citrate is a muscarinic antagonist. Pentoxyverine citrate is a potent antitussive, anticonvulsant, and spasmolytic agent. Pentoxyverine citrate can be used for inhibiting bronchial interceptor, weakening of cough reflex, bronchial smooth muscle relaxation and reduction of airway resistance [4].
    Pentoxyverine citrate (Standard)
  • HY-A0177
    Fominoben

    		GABA Receptor Inflammation/Immunology
    Fominoben is a type of benzamide-based antitussive agent. Fominoben works by acting on the central nervous system to increase alveolar ventilation, thereby improving the blood oxygen levels in patients with pulmonary diseases (COLD). Fominoben can bind to the benzodiazepine receptor binding sites in the brain and also has anti-anxiety and anti-convulsant effects. Fominoben can be used in research on hypoxemia.
    Fominoben
  • HY-105642
    Isoaminile

    		mAChR nAChR Others
    Isoaminile is an orally active antitussive agent. Isoaminile can be used for cough related research .
    Isoaminile
  • HY-B2185
    Tipepidine citrate

    		Dopamine Receptor Potassium Channel AMPK Neurological Disease Metabolic Disease Inflammation/Immunology
    Tipepidine citrate is a non-narcotic antitussive agent. Tipepidine citrate reversibly inhibits dopamine D2 receptor-mediated GIRK current (IDA(GIRK)), thereby activating VTA dopamine neurons, with an IC50 of 7.0 μM for IDA(GIRK). Tipepidine activates AMPK. Tipepidine citrate has antidepressant-like effects. Tipepidine citrate enhances the analgesic effect of Carbamazepine (HY-B0246). Tipepidine citrate improves adipose tissue fibrosis and glucose intolerance in high-fat diet-induced obese mice .
    Tipepidine citrate
  • HY-N18266
    10-Hydroxycroomine

    		Others Inflammation/Immunology
    10-Hydroxycroomine is a croomine-type alkaloid. 10-Hydroxycroomine can be isolated from the roots of Stemona tuberosa. 10-Hydroxycroomine produces a non-statistically significant reduction in Citric acid (HY-N1428)-induced coughing. 10-Hydroxycroomine can be used for the research of cough .
    10-Hydroxycroomine

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