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bacteria label

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Akt (14) Amino Acid Derivatives (2) Antibiotic (74) Antifolate (3) Apoptosis (18) Arginase (12) Aryl Hydrocarbon Receptor (3) ATP Synthase (1) Aurora Kinase (1) Autophagy (10) Bacterial (128) Beta-lactamase (3) Biochemical Assay Reagents (3) c-Met/HGFR (1) Calcium Channel (2) Cholinesterase (ChE) (1) COX (7) Cytochrome P450 (2) DNA/RNA Synthesis (11) Drug Derivative (2) Drug Intermediate (1) Drug Metabolite (3) EAAT (2) Endogenous Metabolite (38) Environmental Pollutants (2) Estrogen Receptor/ERR (2) Fluorescent Dye (8) Fungal (18) FXR (2) G protein-coupled Bile Acid Receptor 1 (1) GABA Receptor (2) Glycosidase (3) GSK-3 (1) Hedgehog (2) Heme Oxygenase (HO) (1) HIV (2) HSV (8) IGF-1R (1) Influenza Virus (2) Insecticide (3) Isotope-Labeled Compounds (133) JNK (3) Keap1-Nrf2 (1) MicroRNA (2) Monoamine Oxidase (2) Necroptosis (2) NF-κB (7) NO Synthase (7) Orthopoxvirus (2) P-glycoprotein (1) p38 MAPK (4) Parasite (8) Penicillin-binding protein (PBP) (4) PERK (1) PI3K (2) PPAR (6) Reactive Oxygen Species (ROS) (2) Sodium Channel (2) Topoisomerase (3) TRP Channel (1)
By Research Areas:	Cancer (25) Cardiovascular Disease (5) Infection (138) Inflammation/Immunology (14) Metabolic Disease (9) Neurological Disease (16)
Click Chemistry:	Labeling and Fluorescence Imaging (2) Azide (2) Alkynes (2)

174

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

157

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0107S

Tetracycline-d6	Bacterial Antibiotic	Infection
Tetracycline-d₆ is the deuterium labeled Tetracycline. Tetracycline is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.

HY-151642

3-Azido-D-alanine	Amino Acid Derivatives	Infection
3-Azido-D-alanine is an azido-modified D-alanine (HY-41700). 3-Azido-D-alanine can be used in the research of click chemistry labeling . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-B0510S

Trimethoprim-d9	Antifolate Bacterial Antibiotic	Infection
Trimethoprim-d₉ is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment .

HY-151642A

3-Azido-D-alanine hydrochloride	Amino Acid Derivatives	Infection
3-Azido-D-alanine hydrochloride is an azido-modified D-alanine (HY-41700) hydrochloride. 3-Azido-D-alanine hydrochloride can be used in the research of click chemistry labeling . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-B1008S

4-Aminobenzoic acid-d4 PABA-d₄; Vitamin Bx-d₄; Vitamin H1-d₄; p-Aminobenzoic acid-d₄	Isotope-Labeled Compounds Endogenous Metabolite	Others
4-Aminobenzoic acid-d₄ is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

HY-N0216S1

Benzoic acid-13C6	Bacterial Fungal Endogenous Metabolite	Infection
Benzoic acid- ¹³C₆ is the ¹³C-labeled Benzoic acid. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.

HY-17586AS

Dalbavancin-d6 MDL-63397-d₆; BI-397-d₆	Bacterial Antibiotic	Infection
Dalbavancin-d₆ is the deuterium labeled Dalbavancin . Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .

HY-Y0882S1

Hydroxylamine-d3 hydrochloride	Monoamine Oxidase	Cardiovascular Disease
Hydroxylamine-d₃ (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride. Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N₂O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .

HY-B0522S

Ampicillin-d5	Bacterial Antibiotic	Infection
Ampicillin-d₅ is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-B1923S

Piperacillin-d5 Pipracil-d₅	Isotope-Labeled Compounds Antibiotic Bacterial Beta-lactamase Penicillin-binding protein (PBP)	Infection
Piperacillin-d₅ is deuterium labeled Piperacillin. Piperacillin is kind of semisynthetic penicillins. Piperacillin has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin has shown greater activity against β-lactamase-producing organisms than the other penicillins .

HY-B0671S

Vancomycin-d12 TFA	Isotope-Labeled Compounds Antibiotic Autophagy Bacterial	Infection Cancer
Vancomycin-d₁₂ TFA is a deuterium labeled Vancomycin (HY-B0671). Vancomycin is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis .

HY-17580S

Fidaxomicin-d7	Isotope-Labeled Compounds DNA/RNA Synthesis Bacterial Apoptosis Antibiotic	Infection
Fidaxomicin-d₇ (OPT-80-D₇) is the deuterium labeled Fidaxomicin. Fidaxomicin (OPT-80), a macrocyclic RNA polymerase inhibitor, has a narrow spectrum of activity. Fidaxomicin selectively eradicates pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora .

HY-B0318S

Metronidazole-13C2,15N2 1 Publications Verification	Bacterial Parasite Apoptosis Antibiotic	Infection
Metronidazole- ¹³C₂, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.

HY-W007355S

Skatole-d3 3-Methylindole-d₃; 3-Methyl-1H-indole-d₃	Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Autophagy Bacterial Fungal	Others
Skatole-d₃ is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38 .

HY-N1914S1

Ergothioneine-d9 1 Publications Verification L-(+)-Ergothioneine-d₉	Endogenous Metabolite	Others
Ergothioneine-d₉ is the deuterium labeled Ergothioneine. Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant .

HY-B0132S

Norfloxacin-d5	Bacterial Antibiotic	Infection
Norfloxacin-d₅ is the deuterium labeled Norfloxacin. Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase .

HY-Y0264S1

4-Hydroxybenzoic acid-d4	Endogenous Metabolite Bacterial	Infection
4-Hydroxybenzoic acid-d₄ is the deuterium labeled 4-Hydroxybenzoic acid. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.

HY-143831S

Cefepime-d8 sulfate	Isotope-Labeled Compounds Antibiotic Bacterial GABA Receptor	Infection
Cefepime-d₈ (BMY-28142-d₈) sulfate is deuterium labeled Cefepime sulfate. Cefepime sulfate is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC₅₀ of 21.115 mM and a K_i of 35.092 mM. Cefepime sulfate inhibits hPON1 via a non-competitive mechanism and blocks GABA_A receptors. Cefepime sulfate penetrates the outer membrane of Gram-negative bacteria, inhibits the growth of Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamase.

HY-B0479S

Thiamphenicol-d3 Thiophenicol-d₃; Dextrosulphenidol-d₃	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Thiamphenicol-d₃ is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

HY-B0519AS

Tylosin-d3	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Tylosin-d₃ is the deuterium labeled Tylosin. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-D1690A

sBADA	Fluorescent Dye	Others
sBADA is a potent green fluorescent dye that targets and labels peptidoglycan in the cell walls of live bacteria(Ex/Em = 490/510 nm) .

HY-Y0264S

4-Hydroxybenzoic acid-13C6	Isotope-Labeled Compounds	Infection
4-Hydroxybenzoic acid- ¹³C6 is the ¹³C labeled isotope of 4-Hydroxybenzoic acid- ¹³C6.4-Hydroxybenzoic acid is a phenolic derivative of benzoic acid, which can inhibit most Gram-positive bacteria and some Gram-negative bacteria with an IC50 value of 160 μg/mL.

HY-W007355S1

Skatole-d8 3-Methylindole-d₈; 3-Methyl-1H-indole-d₈	Isotope-Labeled Compounds Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Autophagy Bacterial Fungal	Others
Skatole-d₈ is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38 .

HY-N0172S

Caffeic acid-13C3 3,4-Dihydroxycinnamic acid-¹³C₃	Bacterial Fungal	Infection
Caffeic acid- ¹³C₃ is an ¹³C labeled caffeic acid. Caffeic acid is a phytonutrient belonging to the flavonoids. Caffeic acid and its derivatives, are potential antimicrobial agents, chronic infection induced by microbes such as bacteria, fungi, and viruses .

HY-B2233AS

Calcium phosphorylcholine-d9 chloride Phosphocholine-d9 chloride calcium	Endogenous Metabolite Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Calcium phosphorylcholine-d₉ (chloride) is the deuterium labeled Calcium phosphorylcholine chloride. Calcium phosphorylcholine chloride is the main phospholipid component in eukaryotic biofilms. Calcium phosphorylcholine chloride exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Calcium phosphorylcholine chloride exhibits a surprising range of immunomodulatory properties .

HY-W654100

Cefepime-d3 sulfate	Isotope-Labeled Compounds Antibiotic Bacterial GABA Receptor	Infection
Cefepime-d₃ (BMY-28142-d₃) sulfate is deuterium labeled Cefepime sulfate. Cefepime sulfate is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC₅₀ of 21.115 mM and a K_i of 35.092 mM. Cefepime sulfate inhibits hPON1 via a non-competitive mechanism and blocks GABA_A receptors. Cefepime sulfate penetrates the outer membrane of Gram-negative bacteria, inhibits the growth of Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamase.

HY-B0510S2

Trimethoprim-d3	Antifolate Bacterial Antibiotic	Infection
Trimethoprim-d₃is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment .

HY-B0275S

Oxytetracycline-d6	Isotope-Labeled Compounds Antibiotic Bacterial Endogenous Metabolite HSV	Infection
Oxytetracycline-d₆ is deuterium labeled Oxytetracycline. Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .

HY-W005288S

4-Vinylphenol-d4 4-Hydroxystyrene-d₄	Apoptosis Endogenous Metabolite Isotope-Labeled Compounds	Cancer
4-Vinylphenol-d₄ is deuterated labeled 4-Vinylphenol (HY-W005288). 4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

HY-D1689

Rf470DL	Bacterial	Infection
Rf470DL is a rotor-fluorogenic D-amino acid (RfDAA). Rf470DL can be used for labeling bacteria (Ex=470 nm, Em=640 nm) .

HY-147097A

EDA-DA TFA	Bacterial	Infection
EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of *bacteria*. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-Y0264S2

4-Hydroxybenzoic acid-13c	Bacterial Endogenous Metabolite	Infection
4-Hydroxybenzoic acid- ¹³C is the ¹³C labeled 4-Hydroxybenzoic acid . 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC₅₀ of 160 μg/mL .

HY-17395S

Terbinafine-d3 hydrochloride TDT 067-d3 hydrochloride	Isotope-Labeled Compounds Fungal Bacterial Antibiotic	Infection
Terbinafine-d₃ hydrochloride is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a K_i of 30 nM . Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria .

HY-B0200S

Cephalexin-d5 Cefalexin-d₅; Cephacillin-d₅	Antibiotic Bacterial	Infection
Cephalexin-d₅ is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al .

HY-N5142S

α-Terpineol-d3	Bacterial	Infection
α-Terpineol-d₃ is the deuterium labeled α-Terpineol . α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria .α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption .

HY-B0275S1

Oxytetracycline-d3	Isotope-Labeled Compounds Endogenous Metabolite Bacterial Antibiotic HSV	Infection
Oxytetracycline-d₃ is the deuterium labeled Oxytetracycline (HY-B0275). Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .

HY-D1697

OGDA	Fluorescent Dye	Infection
OGDA is a green fluorescent D-amino acid. OGDA is suitable for labeling peptidoglycan in Gram-positive and Gram-negative bacteria .

HY-B0318S1

Metronidazole-d4	Bacterial Parasite Apoptosis Antibiotic	Infection
Metronidazole-d₄ is the deuterium labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.

HY-B1414S

Chloroxylenol-d6 p-Chloro-m-xylenol-d₆; PCMX-d₆	Isotope-Labeled Compounds Bacterial Influenza Virus	Infection
Chloroxylenol-d₆ is the deuterium labeled Chloroxylenol. Chloroxylenol is a broad spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus.

HY-136382S

Sulfachloropyridazine-d4 Sulfachlorpyridazine-d₄	Antibiotic Bacterial	Inflammation/Immunology
Sulfachloropyridazine-d₄ is the deuterium labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria .

HY-N1420AS

Rhamnose-13C monohydrate L-Rhamnose-13C monohydrate	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Rhamnose- ¹³C (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate c

HY-N1420AS2

Rhamnose-13C-2 monohydrate L-Rhamnose-13C-2 monohydrate	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Rhamnose- ¹³C-2 (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate

HY-N0216S2

Benzoic acid-13C	Bacterial Fungal Endogenous Metabolite	Infection
Benzoic acid- ¹³C is the ¹³C-labeled Benzoic acid. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.

HY-B1256S

Cefuroxime-d3	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Cefuroxime-d₃ is deuterium labeled Cefuroxime (sodium). Cefuroxime sodium is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime sodium has a broad spectrum activity against Gram-positive and Gram-negative bacteria .

HY-W654101

Cefotaxime-d3 Cefotaxim-d₃; HR-756-d₃	Isotope-Labeled Compounds Antibiotic Bacterial	Infection
Cefotaxime-d3 is the deuterium labeled Cefotaxime (HY-A0088A). Cefotaxime is the β-lactamase stable cephalosporin and the third-generation cephalosporin antibiotic. Cefotaxime possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .

HY-17395AS

Terbinafine-d7 TDT 067-d₇	Isotope-Labeled Compounds Fungal Bacterial Antibiotic	Infection
Terbinafine-d₇ is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a K_i of 30 nM . Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria .

HY-W654157

Dicloxacillin-13C4 sodium hydrate	Antibiotic Isotope-Labeled Compounds Bacterial	Infection
Dicloxacillin- ¹³C₄ sodium hydrate is the ¹³C-labeled Dicloxacillin Sodium hydrate (HY-B0977). Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to study infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus .

HY-B0324AS

Crystal Violet-d6 Basic Violet 3-d₆; Gentian Violet-d₆; Methyl Violet 10B-d₆	Isotope-Labeled Compounds	Others
Crystal Violet-d₆ is the deuterium labeled Crystal Violet (HY-B0324A). Crystal Violet, also known as Gentian violet, methyl violet 10B, is a triphenyl-methane, an alkaline dye that binds to DNA in the nucleus of a cell, staining it a deep purple. It is often used for Gram staining to classify bacteria, or for cell or histological staining .

HY-136406S

Bongkrekic acid-13C28 1 Publications Verification	Isotope-Labeled Compounds ATP Synthase	Cancer
Bongkrekic acid- ¹³C₂₈ is the ¹³C labeled Bongkrekic acid (HY-136406). Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport .

HY-10394S1

Linezolid-d8 PNU-100766-d₈	Antibiotic Bacterial Isotope-Labeled Compounds	Infection
PNU-100766-d₈ is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .

Cat. No.	Product Name	Type

HY-D1689

Rf470DL	Fluorescent Dyes
Rf470DL is a rotor-fluorogenic D-amino acid (RfDAA). Rf470DL can be used for labeling bacteria (Ex=470 nm, Em=640 nm) .

HY-D2430

Chitosan-PEG-Cy3

Fluorescent Dyes

Chitosan-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, Chitosan and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Chitosan exhibits antimicrobial activity against various bacteria and fungi .

HY-D1189

YADA

Lucifer Yellow 3-amino-D-alanine

Fluorescent Dyes

YADA (Lucifer Yellow 3-amino-D-alanine) is a conjugate of the fluorescent dyes Lucifer yellow and D-alanine, which is a green-yellow fluorescent dye. YADA is suitable for labeling peptidoglycans in living bacteria that can be incorporated into the cell wall where they are being synthesized. YADA has a large Stokes shift and a wide emission spectrum, allowing excitation through a purple light source and detection using a green filter. YADA showed good water solubility, light stability and thermal stability.

HY-D1690

sBADA TFA	Fluorescent Dyes
sBADA TFA is a potent green fluorescent dye that targets and labels peptidoglycan in the cell walls of live bacteria(Ex/Em = 490/510 nm) .

HY-D3389

sCy5DL-amide

Fluorescent Dyes

sCy5DL-amide is an amidated fluorescent D-amino acid conjugated to Sulfo-Cyanine 5, and a peptidoglycan labeling agent. sCy5DL-amide incorporates into bacterial peptidoglycan cell wall via transpeptidase-mediated reactions, replacing the fourth or fifth D-amino acid of the peptidoglycan stem peptide for visualization of nascent peptidoglycan biosynthesis. sCy5DL-amide produces clear cell outline, septum labeling, and high localization density in Bacillus subtilis, including a 'V-shape' pattern at cell-cell contact areas. sCy5DL-amide exhibits robust incorporation into Gram-positive bacteria and mycobacteria, with reduced incorporation into Gram-negative bacteria (Ex/Em = 646/666 nm) .

HY-D3391

RMR-Tre

Fluorescent Dyes

RMR-Tre is a fluorescent probe targeting the mycobacterial acyltransferase Ag85. Under the catalysis of Ag85, RMR-Tre undergoes 6-position mycoloylation and anchors to the mycobacterial membrane, while achieving fluorescence activation by inhibiting the intramolecular twisted charge transfer state transition. RMR-Tre can distinguish live mycobacteria from dead ones through metabolism-driven labeling, enabling rapid, wash-free, low-background detection of viable bacteria. RMR-Tre reports the drug resistance of Mycobacterium tuberculosis via the trehalose catalytic shift activity readout associated with TreS. In addition, RMR-Tre can be combined with flow cytometry or high-content imaging techniques to visualize and quantitatively analyze the metabolic heterogeneity of Mycobacterium tuberculosis related to persistence and drug resistance. RMR-Tre is widely used in tuberculosis-related research .

Cat. No.	Product Name	Type

HY-NP0147

Wheat Germ Agglutinin (Fluorescein)

1 Publications Verification

WGA (Fluorescein)

Biochemical Assay Reagents

Wheat Germ Agglutinin (WGA) Fluorescein is a classic fluorescent label that specifically binds to sugar residues such as N-acetylglucosamine, N-acetylneuraminic acid and sialic acid. Wheat Germ Agglutinin Fluorescein performs regionally differential fluorescent staining of the ocular surface epithelial glycocalyx to assess its integrity, and causes no damage to the eye at safe concentrations. Wheat Germ Agglutinin Fluorescein is also used for staining structures including red blood cells, cultured cells, bacteria and pine wood nematodes, and facilitates the isolation of wheat-associated plant-growth-promoting rhizobacterial strains. Wheat Germ Agglutinin Fluorescein can be applied to the detection of ocular glycocalyx integrity and the research of related diseases such as pine wilt disease .

HY-W001952

6-Bromo-2-naphthol

Biochemical Assay Reagents

6-Bromo-2-naphthol is an RTP (real-time polymerase chain reaction) probe that forms a 1:1 or 2:1 complex with β-cyclodextrin (β-CD). 6-Bromo-2-naphthol is capable of real-time monitoring of PCR reactions and quantification of specific nucleic acid sequences. RTP probes are a class of small DNA or RNA sequences labeled with fluorescent dyes and quencher molecules, which can be widely used in gene expression analysis, SNP genotyping, and pathogen detection. 6-Bromo-2-naphthol embeds into the cyclodextrin cavity through hydrophobic interactions, inhibits the oxygen quenching effect, and emits a phosphorescent signal at room temperature. 6-Bromo-2-naphthol can also be used as an intermediate for the synthesis of antibacterial azo dyes, and its derivatives show antibacterial activity against Staphylococcus aureus, Escherichia coli and other bacteria .

Cat. No.	Product Name	Target	Research Area

HY-P10913

HYNIC-UBI29-41	Bacterial	Infection
HYNIC-UBI29-41 is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41 (HY-P10364) (HY-P10364). HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) .

HY-P10913A

HYNIC-UBI29-41 TFA	Bacterial	Infection
HYNIC-UBI29-41 TFA is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41 (HY-P10364). HYNIC-UBI29-41 TFA retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 TFA can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) .

HY-P11330

L-Ala-D-Glu-m-DAP-D-Ala-D-Ala	Bacterial	Infection
L-Ala-D-Glu-m-DAP-D-Ala-D-Ala is a key structured peptide of peptidoglycan of gram-negative bacteria. Peptidoglycan is a network of L-Ala-D-Glu-m-DAP-D-Ala-D-Ala cross-linking the repeated units of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc). L-Ala-D-Glu-m-DAP-D-Ala-D-Ala can be used for bacterial metabolic labeling research .

Cat. No.	Product Name		Classification

HY-151642

3-Azido-D-alanine		Labeling and Fluorescence Imaging Azide
3-Azido-D-alanine is an azido-modified D-alanine (HY-41700). 3-Azido-D-alanine can be used in the research of click chemistry labeling . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151642A

3-Azido-D-alanine hydrochloride		Labeling and Fluorescence Imaging Azide
3-Azido-D-alanine hydrochloride is an azido-modified D-alanine (HY-41700) hydrochloride. 3-Azido-D-alanine hydrochloride can be used in the research of click chemistry labeling . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-147097A

EDA-DA TFA		Alkynes
EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of *bacteria*. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-147097

EDA-DA		Alkynes
EDA-DA, a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. Peptidoglycan (PG), an essential structure in the cell walls of the vast majority of bacteria, is critical for division and maintaining cell shape and hydrostatic pressure . EDA-DA is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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