52 Results for "

cell attachment

" in MedChemExpress (MCE) Product Catalog:
Products (52)

52 Results for "cell attachment" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-19344
CAS No.: 1025967-78-5
Synonyms: SAR 1118; SHP-606
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease .
loading...
    loading...
11
11 Publications Verification
Cat. No.: HY-19344A
CAS No.: 1119276-80-0
Synonyms: SAR 1118 sodium; SHP-606 sodium
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

Lifitegrast (SAR 1118) sodium is a potent integrin antagonist. Lifitegrast sodium blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast sodium can be used for researching dry eye disease .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-15440
CAS No.: 701213-36-7
Purity:  98.70%
Synonyms: BMS-626529
Target:  

HIV

Research Areas:  

Infection

Temsavir (BMS-626529) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4 + T cells.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-15440A
CAS No.: 864953-29-7
Purity:  99.52%
Synonyms: BMS-663068
Target:  

HIV

Research Areas:  

Infection

Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4 + T cells.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-15440B
CAS No.: 864953-39-9
Purity:  99.78%
Synonyms: BMS-663068 Tris
Target:  

HIV

Research Areas:  

Infection

Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl proagent of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4 + T cells.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-126437B
CAS No.: 25988-63-0
Research Areas:  

Others

Poly-L-lysine (hydrobromide) (MW 70000-150000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 70000-150000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 70000-150000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-125474
CAS No.: 9000-07-1
Carrageenan is an antiviral and anticancer agent. Carrageenan inhibits herpes simplex virus (HSV), HIV, and hepatitis A virus (HAV) by directly binding to the viral capsid to block the attachment of viruses such as HPV to HSPG factors on the cell surface. Carrageenan delays and arrests cell cycle progression, exhibits cytotoxicity against HeLa cancer cells, and can be applied to studies related to cervical cancer, genital warts, hepatitis A, and other conditions. Carrageenan also induces acute non-immune inflammation, triggers a three-phase inflammatory response involving the release of multiple proinflammatory mediators, and causes persistent edema, hyperalgesia, and neutrophil recruitment in mice .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-126437A
CAS No.: 26124-78-7
Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide. .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-126437H
CAS No.: 25988-63-0
Poly-L-lysine hydrobromide (MW 4000-15000) is a positively charged amino acid polymer that acts as a non-specific attachment factor for cells. Poly-L-lysine hydrobromide (MW 4000-15000) enhances the electrostatic interaction between the negative ions of the cell membrane and the surface of the culture medium, thereby promoting the adhesion of cells to solid substrates. Poly-L-lysine hydrobromide (MW 4000-15000) can be used for gene delivery .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-120427
CAS No.: 154212-56-3
Purity:  98.82%
Synonyms: NSC 658586
Target:  

CCR CXCR HIV HSV

Research Areas:  

Infection Inflammation/Immunology

Cosalane (NSC 658586) is a CCR7 (IC50 = 2.43 μM) and CXCR2 antagonist (IC50 = 0.66 μM). Cosalane is an inhibitor of HIV replication with a wide range of activity against HIV-1 isolates, HIV-2, Rauscher murine leukemia virus, HSV-1, HSV-2 and human cytomegalovirus. Cosalane inhibits both attachment of gp120 to CD4. Cosalane inhibits human and murine CCR7 in response to both CCL19 and CCL21 agonists. Cosalane can be studied in research for HIV or attenuating acute graft-versus-host disease (aGVHD) in allogeneic hematopoietic stem cell transplantation (HSCT) .
loading...
    loading...
Cat. No.: HY-NP010
CAS No.: 9007-34-5
Collagen, rat tail is a kind of collagen extracted from rat tail tendon tissue. Collagen, rat tail stimulates cell growth. Collagen, rat tail is often used as an attachment substrate for cell culture .
loading...
    loading...
Cat. No.: HY-126437C
CAS No.: 25988-63-0
Research Areas:  

Others

Poly-L-lysine (hydrobromide) (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 150000-300000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
loading...
    loading...
Cat. No.: HY-Y1365D
CAS No.: 9000-70-8
Bovine Gelatin, suitable for cell culture can be used for cell culture to induce cell attachment .
loading...
    loading...
Cat. No.: HY-Y1365L
CAS No.: 9000-70-8
Porcine skin Gelatin,suitable for cell culture(high gel strength) can be used to coat cells to improve cell attachment .
loading...
    loading...
Cat. No.: HY-126437E
CAS No.: 25988-63-0
Poly-L-lysine hydrobromide (with a molecular weight of 15,000 - 30,000) is an amino acid polymer with positive charge, and it serves as a non-specific attachment factor for cells. Poly-L-lysine hydrobromide (with a molecular weight of 15,000 - 30,000) can be used for gene delivery and the construction of nano-delivery systems .
loading...
    loading...
Cat. No.: HY-126437J
CAS No.: 25988-63-0
Synonyms: PLL solution 0.01%, sterile-filtered, hydrobromide, MW 150000-300000, for cell culture
Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) has good biocompatibility. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
loading...
    loading...
Cat. No.: HY-126437D
CAS No.: 25988-63-0
Research Areas:  

Others

Poly-L-lysine hydrobromide (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine hydrobromide (MW 150000-300000) has good biocompatibility. Poly-L-lysine hydrobromide (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
loading...
    loading...
Cat. No.: HY-P5558
CAS No.: 917760-16-8
Target:  

VEGFR

Research Areas:  

Neurological Disease

KLTWQELYQLKYKGI is a VEGF mimetic peptide designed based on the VEGF helix sequence 17-25, with the ability to activate VEGF receptors and exert pro-angiogenic biological activity. KLTWQELYQLKYKGI effectively promotes the attachment, spreading and proliferation of human umbilical vein endothelial cells. KLTWQELYQLKYKGI enhances the proliferation, migration and osteogenic differentiation of bone marrow stromal cells (BMSCs). KLTWQELYQLKYKGI synergistically accelerates angiogenesis and bone regeneration in rat cranial defect models. KLTWQELYQLKYKGI can be used for the research of brain tissue engineering and traumatic brain injury repair and biomaterials for bone tissue engineering and bone repair .
loading...
    loading...
Cat. No.: HY-159069
CAS No.: 9010-72-4
Purity:  95.02%
Zymosan (ZM), 95% is a yeast cell wall-derived carbohydrate-rich preparation and immunomodulator. Zymosan (ZM), 95% binds to and activates TLR-2, TLR-4, and Dectin-1 receptor to trigger downstream signaling pathways. Zymosan (ZM), 95% upregulates TLR-2, TLR-4, and TNF-α mRNA expression, increases serum TNF-α levels, and stimulates splenocyte number and viability in mice. Zymosan (ZM), 95% attenuates melanoma growth progression, modulates macrophage marker gene expression, and mediates phagocytosis, ROS generation, and cytokine production. Zymosan (ZM), 95% reduces Connexin 43 protein and mRNA levels, inhibits gap junctional intercellular communication, and induces proinflammatory factor production in human corneal cells. Zymosan (ZM), 95% induces peritoneal inflammation in mice, functions as a drug carrier, and supports fibroblast cell attachment in hydrogel formulations. Zymosan (ZM), 95% can be used for the research of melanoma, tumors, fungal keratitis, ocular surface inflammatory disorders, and peritoneal inflammation .
loading...
    loading...
Cat. No.: HY-Y1365E
CAS No.: 9000-70-8
Porcine skin Gelatin, suitable for cell culture (medium gel strength) can be used to coat cells to improve cell attachment .
loading...
    loading...